Effect of different animal and vegetable fats

Discussion in 'Articles & Scientific Studies' started by miles, Jan 10, 2014.

  1. miles

    miles Member

    Jan 9, 2014
    http://cancerres.aacrjournals.org/conte ... 7.abstract

    Hello, I found this study on the Comparative effects of different animal and vegetable fats on tumours in rats.
    Can anyone explain to me why the study seems to show that that a 20 per cent corn oil diet seems to have been better than 20 per cent beef fat in terms of not facilitating tumours?
  2. 4peatssake

    4peatssake Member

    Feb 7, 2013
    I just had a very quick glance but perhaps the answer is as simple as - because "This work was supported by Grants CA-33240 and CA-24538 from the National Cancer Institute, NIH."
  3. Mittir

    Mittir Member

    Feb 20, 2013
    Few quotes from the study
    If beef tallow does not cause statistically significant change then leave it
    out of conclusion.It is more reasonable to say that Lard increased
    tumor development than just saying animal fat did it.
    They did not do their analysis on fatty acid composition for any of the
    fat they used. They relied on the food supplier. The PUFA content
    of lard is almost identical to USDA data.It has been shown
    that fatty acid composition of non ruminant like pig
    depends largely on dietary fatty acid composition.
    Corn and grain fed pig can have upto 30 percent PUFA.
    Beef tallow also reflects it dietary intake of fatty acids. RP mentioned how so many
    studies use high PUFA lard and blame the results on saturated fat.

    They mentioned that estrogen in animal fat could have been a cause. Then
    they rule out that possibility based on some tests. I do not know if these authors
    are expert in endocrinology. The lead author has a PhD in physiology and specialization
    in Pharmacology. It is a possibility that they made a mistake in measuring estrogen's
    role in tumor development.They clearly do not know the mechanism ..
    They discussed that their results differ from other previous studies particularly
    on PUFA rich oil and beef tallow.

    (Based on statistically insignificant association between beef tallow and tumor)
  4. 4peatssake

    4peatssake Member

    Feb 7, 2013

    Thanks for taking your time to break this down Mittir.
  5. jyb

    jyb Member

    Nov 9, 2012
    It's actually a pretty serious scientific flaw. In terms of scientific rigour, medical research is really closer to psychology (whose top journals famously publish articles with dodgy statistical work because that makes more spectacular findings possible) than science.