Another Aspirin Helps Cancer Study

[lollipop]

Aspirin slows spread of colon, pancreatic cancer in tumor cells

https://www.sciencedaily.com/releases/2016/12/161214100735.htm

 

[papaya]

Wow, Asprin is really amazing. The question is, how do we take it regularly enough for prevention but not too often so that it loses effectiveness? It seems Asprin is a cure all but do we save it for when we really need it so it's highly effective or use it regularly???Right now I basically just use it when I have a headache.

 

[haidut]

This is the actual study. It is one of the few studies that looked at aspirin effects on treating cancer and not just preventing it.
Aspirin therapy reduces the ability of platelets to promote colon and pancreatic cancer cell proliferation: implications for the oncoprotein c-MYC. | Cell Physiology

The key points of the study is that aspirin can stop non-metastatic colon and pancreatic cancer in a dose of about 100mg daily (20uM concentration used in the study). To stop metastatic cancer, much higher concentrations were needed. The good news is metastatic pancreatic cancer was inhibited dose-dependently starting at 1mM (~3g aspirin daily) while metastatic colon cancer reauired higher concentrations of 2.5mM and 5mM (6g - 12g aspirin daily). They say these concentrations require dose of aspirin not likely to be doable in humans, but that is not true. Doses of 96mg/kg aspirin was used in the diabetes II study with obese subjects for 2 weeks. That translated to about 10g+ aspirin daily for most of them due to their weight, and it still produced no ill effects during those 2 weeks. Of course, with a dose above 625mg it is probably wise to add vitamin K, which has anti-cancer effects of its own.