Ammonia May Be The Direct Cause Of Ulcers In The Stomach

Discussion in 'Scientific Studies' started by haidut, Mar 27, 2017.

  1. haidut

    haidut Member

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    The official cause of stomach ulcers is of course still H. pylori infection but up until now the exact mechanism through which the bacteria damages the mucosa was not known. It seems that the bacteria is really good at breaking down urea into ammonia and CO2 and it is the ammonia which does the damage. So, maybe a possible treatment of ulcers (other than antibiotics to kill the bacteria) would be a hefty dose of urea or another chemical that would lower the pH in the stomach.
    I wonder if lowering/chelating ammonia with things like ceylon cinnamon would also have a protective effect...

    Helicobacter pylori moves through mucus by reducing mucin viscoelasticity
    Physicists Uncover Swimming Secrets of H. pylori Bacteria | Research
    "...Not so in stomach mucus. There, H. pylorisecretes an enzyme called urease, which breaks down urea in the stomach into carbon dioxide and ammonia, giving the smell of ammonia to the breath of infected people. Ammonia, a base, reacts with the stomach mucus, raising its pH and liquefying it. “It de-gelled the gel, and this reversible gelation was the key to letting this bacterium get across,” says Bansil, who published this research in Proceedings of the National Academies of Sciences in 2009."
     
  2. nullredvector

    nullredvector Member

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    Why could urea be useful? Wouldn't that be more substrate for ammonia formation?
     
  3. TubZy

    TubZy Member

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    Biotin!!!
     
  4. Pointless

    Pointless Member

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    What's your experience with this? How much did you take? Did you get acne?

    Or are you referring to biotin 's effects on decreasing ammonia?
     
  5. ecstatichamster

    ecstatichamster Member

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    I wonder if urea can help heartburn.
     
  6. Lewistx

    Lewistx Member

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    Can this help with hpylori
     
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