prolactin

  1. haidut

    LSD-derivatives Like Bromocriptine Can Fully Cure Breast Cancer

    Ray wrote about the usage of drugs like bromocriptine as an actual cure for certain types of cancer. He did not specify which cancers but given the causative role of prolactin in both breast and prostate cancer, I'd suspect these two were on his list. These studies below show that prolactin...
  2. haidut

    Prolactin Increases Cortisol Secretion

    I think this is a pretty important study as it provides further evidence of the close relationship between various biomarkers of stress such as prolactin, estrogen, and cortisol. As Ray said, estrogen is really not a female hormone but rather the stress hormone. Prolactin is pretty similar, and...
  3. haidut

    Prolactin As A Causative Agent In Prostate Cancer

    Just wanted to post this, given the almost perfect correlation between prolactin and expression of estrogen "receptors" in tissues. If prolactin is a causative agent in prostate cancer, than the current idea of treating prostate cancer with estrogen is laughable. I also posted a study showing...
  4. beachbum

    Prolactin/tyrosine/dopamine/thyroid

    Prolactin is usually regarded as the hormone of lactogenesis i.e. it causes milk to be produced. But in excess it reduces libido, causes hypogonadism, galactorrhoea and has inflammatory properties too. Production is stimulated by a number of things... stress low dopamine low tyrosine a lack...
  5. S

    THC On Serum Cortisol And Prolactin

    The effects of cannabinoids on serum cortisol and prolactin in humans
  6. P

    Ascorbate Is Essential For Dopamine Action To Inhibit Prolactin Release

    "Many in‐depth reviews related to regulations of prolactin secretion are available. We will, therefore, focus on controversial aspects using personal opinion in this review. The neuroendocrine control of prolactin secretion from the anterior pituitary gland involves multiple factors including...
  7. P

    Dopamine Agonists Both Stimulate And Inhibit Prolactin Release

    Is this study relevant? This would imply dopamin agonists at sufficiently low doses may be giving a particular person an undesired effect, i.e, higher prolactin? Also, It would be interesting to know the concentration of bromocriptine in cacao (it is suggested it contains bromocriptine here, but...
  8. thegiantess

    Breastfeeding?

    Considering I am 6 months post partum, I spend a lot of time chatting with other moms on forums and with friends that have also had babies. It seems that there is a belief that just about every woman can breastfeed if she tries hard enough, and that only like 1% of women are structurally inept...
  9. ecstatichamster

    Prolactin Levels High Compared To Post-orgasm

    orgasm raises prolactin levels. If you have chronically elevated prolactin, how high are these hormone levels compared to post-orgasm levels?
  10. B

    Low Prolactin Bad For Males?

    Any ideas about what's going on here? :idea: "We previously reported that in male patients consulting for sexual dysfunction, low prolactin (PRL) levels were associated with metabolic syndrome (MetS), arteriogenic erectile dysfunction, and incident major cardiovascular events." "In line with...
  11. haidut

    The Obesity "paradox" - Confirmed Once Again

    This study looked at people who had undergone cardiac surgery, so it probably does not apply directly to "healthy" people. However, the findings are pretty telling - if you are unhealthy and about to have a surgical procedure being overweight or mildly obese can save your life...
  12. J

    LOW Prolactin Linked With Sexual Dysfunction In Men

    Given the anecdotal reports as well as at least one study showing that prolactin-lowering drugs can dramatically increase libido (in men and women) and reduce refractory period (in men), I find this study suspect. Still, it reports that LOW prolactin was associated with sexual dysfunction in...
  13. haidut

    Methylene Blue (MB) Lowers Prolactin By Opposing Estrogen

    It looks like methylene blue may have a few tricks up its sleeve in addition to the well-known effects on mitochondria. The studies below show that MB was able to antagonize the effect of estrogen on prolactin, pituitary size, and dopamine levels. http://www.ncbi.nlm.nih.gov/pubmed/11343835...
  14. haidut

    Lowering Prolactin May Lead To Weight Loss

    The study focuses on cabergoline (a prolactin lowering drug with dopaminergic qualities), however the abstract discusses positive results with other anti-prolactin drugs like bromocriptine. In light of the recent study showing serotonin inhibition treating obesity, this is yet another...
  15. cantstoppeating

    Zinc Seems To Acutely Reduce Prolactin

    Zinc may acutely reduce prolactin levels, according to these studies: Zinc: an inhibitor of prolactin (PRL) secretion in humans. http://www.ncbi.nlm.nih.gov/pubmed/2753470 "The response of plasma prolactin (PRL) to oral administration of increasing doses of zinc (25.0, 37.5 and 50.0 mg) was...
  16. haidut

    Vitamin A is dopaminergic and reduces prolactin in humans

    In theory, anything that reduces prolactin will likely also reduce estrogen and vice versa. So, since vitamin A is anti-estrogenic I wondered if there is evidence that vitamin A will lower prolactin and/or increase dopamine. Below is some evidence that vitamin A is indeed dopaminergic and lowers...
  17. haidut

    Stress is a potent stimulator of prolactin and GH release

    It is common knowledge among Peatarians that both prolactn and growth hormone (GH) are stress hormones that ar ebest kept as low as possible. This study shows that things hypoglycemia, surgery and exercise are all potent stimulators of these stress hormones. The last time I talked to my doctor...
  18. haidut

    Estrogen and prolactin required for breast cancer development

    The chemical used was DES, which Ray has written about and though technically not the same as the biological estrogen it does have very similar and more potent effects. Interestingly, just like Ray, said prolactin is a good surrogate for estrogen activity and is required for breast cancer...
  19. haidut

    Oxygen breathing acutely raises prolactin in humans

    Ray has written on the dangers of hyperoxia and its inability to actually increase tissue oxygenation. Now it looks like there is another danger of inhaling pure O2 - raised prolactin. It also looks like hyperoxia increased prolactin more than hypoxia. So, even more reason to raise our CO2 since...
  20. haidut

    Prolactin Is A Good Biomarker For Serotonin / Estrogen Activity

    Prolactin blood tests are more reliable than serotonin and estrogen - i.e. plasma prolactin is a good indicator for its levels everywhere in the body, while estrogen and serotonin can be low in plasma but high in tissues. The study was done on primates, so it should be very similar to humans...
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