parkinson

  1. haidut

    Niacinamide may treat Parkinson Disease (PD)

    A very interesting study, which used a relatively high dose of nicotinamide riboside (NR) to treat Parkinson Disease (PD). The dosage used was 3,000mg daily for 4 weeks and it resulted in improvement of motor and cognitive symptoms of PD, while producing no side effects. The study references...
    • haidut
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    • metabolism nad nad/nadh niacinamide nicotinamide riboside oxphos parkinson vitamin b3
    • Replies: 9
    • Forum: Scientific Studies
  2. haidut

    Parkinson Disease (PD) akin to infectious disease - driven by endotoxin, damaged mitochondria

    Yet another study demonstrating that there is no need for genes or any other hereditary mechanism to explain the cause and development of PD. The study below demonstrated that the presence of damaged mitochondrial DNA in the bloodstream is sufficient to cause all symptoms of PD, and the effects...
    • haidut
    • Thread
    • endotoxin lps mitochondria mtdna parkinson prion tlr4 tlr9
    • Replies: 3
    • Forum: Scientific Studies
  3. haidut

    Parkinson Disease (PD) is metabolic, of gut origin, progesterone to the rescue

    One of the most famous sayings in medicine since antiquity has been Hippocrates' quip that "all disease begins in the gut". Despite millennia that passed since that phrase was first uttered and countless "advances" in our knowledge of diseases, evidence continues to accumulate that the ancients...
    • haidut
    • Thread
    • endotoxin enteric lps microbiome p4 parkinson progesterone vagus
    • Replies: 3
    • Forum: Scientific Studies
  4. AlphaCog

    Robin Williams autopsy revealed he had about 40% loss of dopamine neurons and almost no neurons were free of Lewy bodies throughout his entire brain.

    The terrorist inside my husband's brain by Susan Schneider Williams I am writing to share a story with you, specifically for you. My hope is that it will help you understand your patients along with their spouses and caregivers a little more. And as for the research you do, perhaps this will...
  5. haidut

    Serotonin, SSRI drugs may be the cause of IBD, Parkinson's, diabetes, etc.

    A great new study that points the finger straight at serotonin (5-HT). It has been known since the 1940s that not only is 5-HT produced predominantly in the GI tract, but also that elevated serotonin levels are causally linked to a plethora of chronic conditions, especially various inflammatory...
    • haidut
    • Thread
    • 5-ht autoimmune autophagy cancer diabetes ibd inflammation parkinson serotonin
    • Replies: 31
    • Forum: Scientific Studies
  6. haidut

    Damaged mitochondria may cause 90%+ of Parkinson Disease (PD) cases

    More evidence that yet another "incurable" condition is little more than energy deficit (due to mitochondrial dysfunction) in disguise. In this case the mitochondrial dysfunction was caused by accumulation of mitochondrial debris inside the cell, which has been repeatedly shown by other studies...
    • haidut
    • Thread
    • damage dementia metabolism mitochondria oxphos parkinson stress
    • Replies: 9
    • Forum: Scientific Studies
  7. haidut

    Metabolic (energy) deficiency may be the cause of Parkinson Disease (PD)

    The dogma that PD is just a simple dopamine deficiency manifesting in genetically vulnerable individuals is quickly becoming untenable. It is well-known among clinicians that administering dopamine precursors such as L-Dopa, or selective dopamine agonists such as pramipexole has limited...
    • haidut
    • Thread
    • deficiency energy metabolism mitochondria parkinson pd ros
    • Replies: 25
    • Forum: Scientific Studies
  8. haidut

    Serotonin may cause schizophrenia, Parkinson, and Alzheimer diseases

    One by one, medical myths (slowly) go the way of the Dodo. Two of the most pervasive such myths are that psychotic conditions like schizophrenia are caused by excess dopamine, and Parkinson Disease (PD) is caused by a deficiency of dopamine. Unbeknownst even to most doctors, studies exist...
    • haidut
    • Thread
    • 5-ht alzheimer hallucinations ondansetron parkinson psychosis schizophrenia serotonin
    • Replies: 3
    • Forum: Scientific Studies
  9. haidut

    Red Light Therapy For Parkinson Disease (PD) Begins Human Trials

    A few weeks ago, I posted about a human study demonstrating reversal of age-related vision decline by staring at a red light for just a few minutes a day. The mechanism of action proposed in that study had to do with improved mitochondrial function and energy production. Now, it seems another...
    • haidut
    • Thread
    • cytochrome c energy human metabolism mitochondria parkinson red light
    • Replies: 2
    • Forum: Scientific Studies
  10. haidut

    Parkinson Disease (PD) May Begin In The Gut

    The article below is one of at least 20 I have seen in just 2020 alone that are starting to draw attention to the metabolic/inflammatory origins of yet another neurological disease of "mysterious" origin - namely, Parkinson Disease (PD). What makes this article both interesting and infuriating...
    • haidut
    • Thread
    • 5-ht endotoxin gut inflammation lps microbiome parkinson serotonin
    • Replies: 0
    • Forum: Scientific Studies
  11. haidut

    Simply Inhaling Endotoxin (LPS) May Cause Parkinson Disease (PD)

    The role of endotoxin (LPS) in neurodegenerative diseases is becoming more and more recognized, despite claims by mainstream medicine that LPS only poses danger to people with severely compromised livers. However, even scientists that are aware of the causative role of LPS in those diseases...
    • haidut
    • Thread
    • air brain endotoxin inflammation inhaled lps parkinson
    • Replies: 4
    • Forum: Scientific Studies
  12. haidut

    America’s Favorite Oil Causes Diabetes, Obesity, Autism, And Liver / Brain Disease

    A series of shockingly direct studies that do not shy away from pointing the finger at the real villain in modern public health history - PUFA, and more specifically the "essential" linoleic acid (LA). As the studies demonstrate, soy oil has strikingly detrimental effects on metabolic health and...
    • haidut
    • Thread
    • autism cause corn oil diabetes nafld obesity omega-3 omega-6 parkinson pufa soy oil soybean oil
    • Replies: 0
    • Forum: Scientific Studies
  13. haidut

    Drop In Androgen Levels Causes Parkinson Disease (PD), DHT Reverses It

    Yet another study demonstrating that many of the so-called chronic, degenerative and above all "mysterious" conditions often have quite a simple cause and, potentially, treatment. There is no need for mutated genes or complex interactions of genes with environment that nobody can decipher...
    • haidut
    • Thread
    • 5α-dihydrotestosterone androgen brain castration cns dht dopamine gdnf inos neurodegeneration neurodegenerative neuroinflammation nitric oxide no parkinson parkinson's disease testosterone α-synuclein
    • Replies: 41
    • Forum: Scientific Studies
  14. haidut

    Serotonin Excess, Not Dopamine Deficiency, May Be The Cause Of Parkinson

    One of the most paradigm-challenging studies I have seen this year and, unsurprisingly, mainstream media is pulling all sorts of tricks to avoid naming the culprit directly. Even the press release and the study abstract are worded in a convoluted way, talking about a "serotonin dysfunction"...
    • haidut
    • Thread
    • advance cause decade excess iatrogenic parkinson predict serotonin sert shaking ssri tremor
    • Replies: 26
    • Forum: Scientific Studies
  15. D

    Lower Ceruloplasmin Found In Parkinson’s

    Hi recently I’ve been raving about irons role in proper dopamine function. Also the importance of proper iron function. This led me to ferroxidase (ceruloplasmin) which is the primary enzyme to handle and shuttle iron through cells and transport it through out the body. Found several studies...
  16. haidut

    Bile Acid Stimulates Mitochondrial Function, Could Treat Parkinson And Alzheimer's

    I posted a few studied some time ago showing that bile acids increase metabolism but stimulating the synthesis of T3. This increase in metabolism is perhaps the main mechanism behind the ability of "obesity surgery" to provide long-term benefits for the people who undergo the procedure. Aside...
    • haidut
    • Thread
    • alzheimer's bile acid cure metabolism mitochondria mitochondrial dysfunction neurodegenerative parkinson taurine treatment udca
    • Replies: 22
    • Forum: Scientific Studies
  17. haidut

    Niacinamide May Be A Viable Treatment For Parkinson Disease (PD)

    It looks like the pharma industry is experiencing a resurgence in the search for metabolic therapies with patented chemicals. There must have been at least 50 different studies in 2017 alone with the NAD precursor nicotinamide riboside (NR) for conditions ranging from cancer, to glaucoma, to...
    • haidut
    • Thread
    • disease energy metabolism mitochondria nad nad/nadh nam niacinamide nicotinamide riboside nr parkinson
    • Replies: 8
    • Forum: Scientific Studies
  18. haidut

    Tremor In Parkinson Disease (PD) Is Due To High Serotonin

    The non-motor signs/symptoms of PD (tremor, drooling, slurred speech, etc) have long been thought to be directly due to dopamine deficiency due to the death of the nigrostriatal dopamine neurons. The common treatment for those signs/symptoms and the motor symptoms as well is usually a dopamine...
    • haidut
    • Thread
    • excess parkinson pd serotonin serotonin transporter sert ssri tremor
    • Replies: 20
    • Forum: Scientific Studies
  19. haidut

    Stearic Acid Increases Mitochondrial Function, May Treat Parkinson Disease (PD)

    I posted recently about the ability of dietary stearic acid to reduce abdominal fat accumulation by more than 70%. This study provides some insight as to what the mechanism of action behind that anti-obesity effect may be. The study below found that when stearic acid was fed at a dose of 10% of...
    • haidut
    • Thread
    • metabolism mitochondria mitochondrial respiration parkinson respiration stearate stearic stearic acid
    • Replies: 39
    • Forum: Scientific Studies
  20. haidut

    Niacinamide And Doxycycline May Treat Alzheimer Disease (AD)

    This study is yet another one that shows benefit of raising NAD levels for treating neurodegenerative conditions like AD. There were a few older studies around 2003, which were also done on mice and as a result of those studies a human clinical trial with 3g niacinamide daily (a dose that...
    • haidut
    • Thread
    • alzheimer's cure doxycycline metabolic mitochondria mitochondrial dysfunction nad niacinamide parkinson reverse treat
    • Replies: 7
    • Forum: Scientific Studies
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