• Due to excessive bot signups along with nefarious actors we are limiting forum registration. Keep checking back for the register link to appear. Please do not send emails or have someone post to the forum asking for a signup link. Until the current climate changes we do not see a change of this policy. To join the forum you must have a compelling reason. Letting us know what skills/knowledge you will bring to the community along with the intent of your stay here will help in getting you approved.

lps

  1. haidut

    Cancer cells deprive immune cells of energy by devouring their mitochondria

    In a description that could be a good plot for a horror-movie, the study below demonstrates that the immune failure often seen in cancer is, again, bioenergetic in origin. More specifically, the immune system cells are getting literally the energy (i.e. mitochondria) sucked out of them by cancer...
  2. aliml

    The homeoviscous adaptation to dietary lipids (HADL) model explains controversies over saturated fat, cholesterol, and cardiovascular disease risk

    SFAs play the leading role in 1 of the greatest controversies in nutrition science. Relative to PUFAs, SFAs generally increase circulating concentrations of LDL cholesterol, a risk factor for atherosclerotic cardiovascular disease (ASCVD). However, the purpose of regulatory mechanisms that...
  3. haidut

    Endotoxin (LPS) may directly cause cancerization of normal cells

    A very interesting new study, which confirms the direct causal role LPS has in chronic inflammatory diseases, and especially in cancer. In addition, the study may answer one of the long-standing critiques the medical establishment has always had against the hypothesis that LPS causes cancer (and...
  4. haidut

    PUFA required for periodontal disease, aspirin may help

    It is common knowledge even among mainstream dentists that periodontal disease is caused by bacteria accumulating under the gums, which over time leads to chronic inflammation and thus destruction of both gum tissue and the alveolar/jaw bone underneath the gums. Another "new" discover is that...
  5. haidut

    Endotoxin (LPS) causes rheumatoid arthritis...and COVID-19

    A great new study, which is perhaps the first to directly point the finger at endotoxin as perhaps the main cause of rheumatoid arthritis (RA). RA is an "autoimmune" condition and not only shares symptoms with other similar conditions such as Lupus, psoriasis, MS, etc, but now all of them are...
  6. haidut

    Endotoxin (LPS) as a cause of liver disease, obesity and diabetes

    The first article below is actually about praising fermented foods, which I don't really agree with. So, I am posting it mostly because of the quote on endotoxin/LPS, which is a very rare finding in published medical literature since medicine does not recognize chronic, low-grade endotoxemia as...
  7. haidut

    Blocking the endotoxin receptor (TLR4) may prevent / treat hearing loss

    I did a post a few months ago on the connection between tinnitus and serotonin - i.e. using anti-serotonin drugs may treat tinnitus. Since tinnitus is almost always a precursor state to hearing loss (and eventually deafness), the two conditions obviously go hand-in-hand and are likely caused by...
  8. haidut

    Endotoxin (LPS) may be the cause of fatal lung damage in COVID-19

    Yet another study, which demonstrates that there is virtually no disease (acute of chronic, infections or not) where the infamous LPS does not play a causative role. As it turns out, the often fatal inflammatory reaction (cytokine storm) that usually kills patients with COVID-19 in ICU, is...
  9. haidut

    Silica, present in most supplements/food, activates the endotoxin receptor (TLR4)

    Many of my readers know about the health risks of silica - a substance doctors and pundits call completely "benign, present in virtually all commercially sold dietary supplements and also in most commercially sold food (even organic ones!). The most commonly used form commercially is silicon...
  10. shine

    L. plantarum protects testicles & lowers inflammation/endotoxin

    It is well known that phtalates used in plastics are endocrine disruptors and damage testicular tissue. This study is showing that Lactobacillus plantarum (LP) alleviates testicular damage, increases testosterone back to normal levels, lowers inflammatory mediators like TNF-a, IL-1b and IL-6 and...
  11. Ismail

    Endotoxin (LPS) drives CD38 expression and therefore seems to effect NAD levels

    How To Inhibit CD38 As We Age | LPS Drives CD38 Expression | Prof Covarrubias Interview Series Ep5
  12. haidut

    Endotoxin (LPS) as a cause of systemic inflammation seen in obesity

    Yet another study implicating the great villain of systemic health - endotoxin / LPS. It is well-known that most people with obesity have high levels of inflammatory biomarkers both in their tissues and bloodstream. The study below demonstrates that the inflammation seen in adipose tissue of...
  13. haidut

    Endotoxin behind the mortality of Black Death and 1918 Flu pandemics

    As many of my readers know, many/most people dying from COVID-19 develop either sepsis and/or respiratory failure. Endotoxin (LPS) is now a known cause behind both of these conditions, as a virus by itself has no known mechanism of causing a cytokine storm. As much as I revile the term...
  14. haidut

    Asthma Can Be Caused By Endotoxin (LPS). From Air Filters

    Not a clickbait title but the actual (and fascinating) findings of several studies. I think the biggest find here is that endotoxin (LPS) can directly cause asthma and exacerbate already existing asthma. To my knowledge, while mainstream medicine does admit that asthma is an inflammatory...
  15. Tristan Loscha

    Parkinsonism As A Third Wave Of The COVID-19 Pandemic?

    Parkinsonism as a Third Wave of the COVID-19 Pandemic? Article type: Review Article Authors: Beauchamp, Leah C.a; b | Finkelstein, David I.a | Bush, Ashley I.a; c | Evans, Andrew H.d | Barnham, Kevin J.a; b; c; * Affiliations: [a] Florey Institute of Neuroscience and Mental Health, Parkville...
  16. haidut

    Activation Of The Endotoxin Receptor (TLR4) May Cause Hearing Loss

    There is currently an epidemic of tinnitus (ear ringing) and hearing loss in virtually all developed countries. Experts are scratching heads and are failing to come up with a reason/explanation for this epidemic. As it often happens, the cause is often hidden in plain sight and if one follows...
  17. haidut

    Parkinson Disease (PD) May Begin In The Gut

    The article below is one of at least 20 I have seen in just 2020 alone that are starting to draw attention to the metabolic/inflammatory origins of yet another neurological disease of "mysterious" origin - namely, Parkinson Disease (PD). What makes this article both interesting and infuriating...
  18. haidut

    Simply Inhaling Endotoxin (LPS) May Cause Parkinson Disease (PD)

    The role of endotoxin (LPS) in neurodegenerative diseases is becoming more and more recognized, despite claims by mainstream medicine that LPS only poses danger to people with severely compromised livers. However, even scientists that are aware of the causative role of LPS in those diseases...
  19. haidut

    Endotoxin (LPS) Can Trigger Social Withdrawal / Isolation

    If you talk to a doctor about endotoxin (LPS), he/she will most likely give you a blank stare as this topic is very rarely covered in medical schools and the little coverage it gets simply states that endotoxin is never an issue in most people as the liver will quickly deactivate it. Yet, what...
  20. haidut

    Prenatal Stress Ups Serotonin, Which Causes Autism And Mental Disease In Offspring

    Another good study, which not only corroborates the causative role of elevated serotonin in a number of behavioral disorders in children (which extend into adulthood) but demonstrates the key role of endotoxin (LPS) in that process. Namely, the pregnant animals exposed to stress who had sterile...
Top