kidney disease

  1. haidut

    Diabetic kidney damage driven by high fat & low glucose oxidation, glycine can treat it

    This is yet another study that calls into serious doubt the main dogma of diabetic pathology provided by allopathic medicine. Namely, mainstream medicine claims that the well-known kidney damage occurring in majority of advanced cases of diabetes II is caused by the elevated blood glucose in...
  2. Candeias

    Taurine and its vast renoprotective capacity

    After some research I was impressed by the countless studies related to Taurine and kidney protection, so I will post some of ones here: Protection of Taurine Against Arsenic-Induced DNA Damage of Mice Kidneys "(...) Pathologic changes and DNA damage in the mice kidney were examined by HE...
  3. Candeias

    Renoprotective effects of Cyproheptadine

    Cyproheptadine, a SET7/9 inhibitor, reduces hyperglycaemia-induced ER stress alleviating inflammation and fibrosis in renal tubular epithelial cells "Results: SET7/9 and H3K4Me1 expression significantly increased with ER stress, inflammation, apoptosis, and fibrosis, in-vivo and in-vitro under...
  4. Limon9

    Elevated Free Fatty Acids (FFA) Are Associated With Cancer, Stroke, Cardiovascular Mortality

    A high serum-free fatty acid level is associated with cancer. J Cancer Res Clin Oncol. 2020 Mar;146(3):705-710. Zhang L, Han L, He J, Lv J, Pan R, Lv T. High free fatty acid level is associated with recurrent stroke in cardioembolic stroke [CE] patients. Neurology. 2014 Apr 1;82(13):1142-8...
  5. haidut

    Estrogen Can Both Cause And Exacerbate Lupus

    A quick post as a response to a recent argument I had over email with an endocrinologist who follows me on Twitter. His claim was that the causes of Lupus are currently unknown but are likely "multifactorial" and me ascribing such causes to "isolated peculiarities" such as endotoxin (LPS) or...
  6. haidut

    Aromatase Inhibitor (AI) + DHT Combo May Reverse Kidney Disease (CKD)

    A truly great study for a number of reasons. First, it cites extensive evidence that male patients with diabetes (both types) have low androgens and high estrogen (estradiol). The association between this endocrine abnormality and the severity of diabetes is apparently quite strong, yet it is...
  7. charlie

    Vitamin B1 Could Reverse Early-stage Kidney Disease In Diabetes Patients

    "The team has discovered taking high oral doses of thiamine can dramatically decrease the excretion of albumin and reverse early stage kidney disease in type 2 diabetes patients. In a paper published online in the journal Diabetologia, the team show 300 mg of thiamine taken orally each day for...
  8. Tristan Loscha

    Monocyte Mitochondrial Function In Calcium Oxalate Stone Formers

    Monocyte Mitochondrial Function in Calcium Oxalate Stone Formers Urology. Author manuscript; available in PMC 2017 Jul 1. Published in final edited form as: Urology. 2016 Jul; 93: 224.e1–224.e6. Published online 2016 Mar 10. doi: 10.1016/j.urology.2016.03.004 PMCID: PMC4914421 NIHMSID...
  9. haidut

    Increased Fat Oxidation Is The Cause Of Kidney Damage

    At least in diabetes, according to the study below. Peat mentioned in several of his articles and interviews that the kidney damage so commonly seen in both type I and II diabetes patients is due to increased PUFA oxidation and decreased glucose oxidation. He also said that the same mechanism...
  10. haidut

    Niacinamide May Treat (acute) Kidney Failure (AKI) - Human Study

    It seems modern medicine is slowly starting to recognize the role of energy in organ health, and more specifically the role of NAD/NADH ratio in variety of diseases long thought to be mostly mechanism in origin. A few months ago, I posted a study on raising NAD levels with nicotinamide riboside...
  11. Giraffe

    Itching: Is It Your Kidneys?

    Peat said that too little calcium and vitamin D and too much phosphate lead to kidney degeneration, and supplementing those "in many cases will correct the whatever the liver and kidney problem is." [source] I found a couple of studies that link itching (and a couple of other skin and nail...
  12. haidut

    Low-dose Aspirin As Treatment For Kidney Disease / Failure

    Just wanted to post here as diabetes is perhaps the most common chronic disease in the world and many diabetes sufferers have kidney disease, which is considered irreversible. However, as this clinical trial states (and as Peat said as well), the kidney damage seems to be due to inflammation...
  13. haidut

    Low-dose Emodin Can Change Gut Microbiome And Alleviate Kidney DiseaseHere We Utilized A Rat CKD Mod

    As most people here know Ray is not in favor of "probiotics" supplements, with the possible exception of BioSporin. This study found that an enema with low-dose emodin changed the microbiome in a way that eliminated uremic toxins in a model of kidney disease and also alleviated the pathology of...
  14. haidut

    Anti-acid (PPI) Drugs Commonly Used For GERD Lead To Kidney Failure

    I have long suspected that PPI drugs are very dangerous based on my observations of friends having bone problems and fractures typically seen in people 30-40 years older. The PPI drugs affect calcium and magnesium metabolism in ways that are just beginning to be elucidated and prescribing them...
  15. haidut

    Heartburn Drugs (ppi) Linked To Chronic Kidney Disease

    This study follows the previous once implicating PPI drugs like Nezium and Prevacid in bone fractures, pneumonia, and bacterial infections. Typically, chronic kidney disease is something only people with diabetes and very old people have to be concerned about, however as you can see taking a PPI...
  16. S

    Colas Associated With Increased Risk of Kidney Disease

    Drinking 2 or more colas per day was associated with increased risk of chronic kidney disease. Results were the same for regular colas and artificially sweetened colas . Noncola carbonated beverages were not associated with chronic kidney disease.
  17. haidut

    Thiamine Reverses Diabetic Kidney Damage In Humans

    The study used what they consider a "high" dose of 300mg thiamine and duration was 3 months. In 35% of the patients the damage disappeared completely. ... 092149.htm ... ur-kidneys "...In a double-blind...
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