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Low Serum Calcium May Increase Risk Of Sudden Cardiac Death


Mar 18, 2013
USA / Europe
The rate of sudden cardiac arrest (SCA), which almost always fatal, has increased several fold in the last 2 decades and especially in people younger than 40. At the same time the rate of soft tissue calcification has increased and it is now estimated that even children as young ad 8 have some degree of vascular calcification. This has led to public policy measures aimed at convincing the population that dietary calcium is dangerous, so it needs to be restricted. However, as Peat wrote in his article about the "calcium paradox", the condition of these people can never improve until they actually increase their calcium intake to at least 2g daily.
This latest study below shows that SCA is possibly caused by low serum calcium. While the study says that more studies are needed before official public policy measures can be taken, increasing dietary calcium is one possible intervention to prevent SCA.

Low Serum Calcium May Increase Risk of Sudden Cardiac Arrest

"...Findings of a new study published in Mayo Clinic Proceedings have potential implications for mechanisms as well as prevention of SCA. Sudden cardiac arrest (SCA) is fatal for over 90% of patients, and more than half of men and close to 70% of women who die of SCA have no clinical history of heart disease prior to this cardiac event. It is one of the leading causes of death in the United States and kills more people than any single cancer. Many patients who suffer SCA would not be considered high risk under current guidelines. These sobering facts drive the search for simple and relatively inexpensive ways to identify individuals at higher risk for SCA. In a study in Mayo Clinic Proceedings, researchers found that individuals with lower levels of calcium in the blood, which is easily monitored, are more likely to experience SCA than those with higher calcium levels."

"...While these results should be interpreted with caution, Dr. Lee recommends that (1) serum calcium levels should be examined and followed longitudinally more carefully, (2) low serum calcium levels may be considered a potential risk factor for SCA in the community, and (3) more research is necessary to determine whether patients in the lowest quartile of serum calcium would benefit from higher dietary calcium intake or calcium supplementation."


Jun 8, 2017
This is not an undisputed finding, a link between SCL and soft-tissue calcification also needs to be established, and controlling for MANY variables.


Aug 6, 2017
"All cell death is characterized by an increase of intracellular calcium...." "Increase of cytoplasmic free calcium may therefore be called 'the final common path' of cell disease and cell death. Aging as a background of diseases is also characterized by an increase of intracellular calcium. Diseases typically associated with aging include hypertension, arteriosclerosis, diabetes mellitus and dementia."

My guess would be that since the cells for some reason hyperaccumulate calcium, it is seen as a decrease in serum concentration. Mg deficiency might be one potential explanation.


Apr 21, 2018
Increasing magnesium seems reasonable rather than pushing the calcium:magnesium ratio ever higher

That said I think a 2:1 ratio is fine thus 2g calcium 1g magnesium, very much doable.


New Member
May 4, 2021
I am still looking for answers on a lot of subjects regarding my health and I am not sure of much but from my readings I would tend to think that an adequate level of T4 and T3 can slowly improve this problem.
From my point of view enough T4 makes it possible to activate B2 in the form FAD or FMN which makes it possible to activate B6 in the form PLP and which in turn allows a better absorption of magnesium. And enough T3 to activate/stimulate the Na k atpase pumps to extract calcium and sodium from the cells and fill them with magnesium and potassium. It may be a bit simplistic, but that’s my understanding.

On this subject of hypocalcemia, I was also wondering if people who react badly to a supplement of K2 could not be hypocalcemic. Would K2 not allow only to recover calcium from the blood and thus create even more problems in hypocalcemic people. K2 that recovers calcium from cells would look like magic... maybe not?
I may be far from the truth, but you never know. Just a thought.
Having used reverso for translation I hope it will be understandable.
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