Perry Staltic
Member
- Joined
- Dec 14, 2020
- Messages
- 8,186
Spank me harder daddy
No spanking for you. You're on your own.
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Spank me harder daddy
Acidosis is what ages you.
Starting around 23-25 the kidneys cannot create enough Bicarbonate to deal with modern Diets Heavily Consuming Animal Proteins.
Well documented on @Amazoniac Post here.
"The Primary Sources Of Acidity In The Diet Are Sulfur-containing AAs, Salt, And Phosphoric Acid"
- Acidosis: An Old Idea Validated by New Research (the author appears to be credible, you can tell because he's wearing a tie and has his arms crossed) "The idea that “being too acid” contributes to disease susceptibility, especially cancer, has been around for a long time in the...raypeatforum.com
Acidosis-->Cortisol-->Wrecking Ball
"
Acid-base balance in the body influences adrenal hormone production of cortisol. When bicarbonate [HCO3- levels are low, the kidneys upregulate glutaminase activity and trigger cortisol production [35-37]." "Dietary induction of acidosis increases serum cortisol concentrations [38]."
"Cortisol activates the tryptophan metabolism pathway which is carried out by rate-limiting enzymes of tryptophan catabolism, 2,3-dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO). Cortisol directly stimulates TDO activation and may augment IDO activity indirectly through inflammatory cytokine signaling such as interferon gamma [49,50]. Excessive or chronic cortisol production acquired from a ‘Western’ dietary lifestyle could play a role in augmenting the tryptophan metabolism pathway and drive downstream molecular events that promote carcinogenesis."
"Upregulated cortisol bioactivity driven by diet-induced acidosis may be a factor in metabolic syndrome by promoting insulin resistance. Chronic hyperglucocorticoidism upregulates visceral obesity while reducing insulin sensitivity mainly in visceral adipocytes which appear to be more responsive to cortisol than subcutaneous adipocytes due to higher expression levels of glucocorticoid receptors [58,59]."
"Acidosis associated insulin resistance through cortisol activity may result in compensatory pancreatic insulin secretion and higher levels of circulating insulin in the serum, a condition known as hyperinsulinemia." As Travisord would say: [sick]"
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I supplement Magnesium and Potassium Citrates on 1: 4.8 ratio. These alkalinze the cells and the citrate is converted into bicarbonate almost entirely.
"HCO3- levels are low, the kidneys upregulate glutaminase activity and trigger cortisol production [35-37]."
1 Hair volume trippled(cortsiol tank)
2 Testosterone Went to the moon(cortisol tank)
3 Have an 8 pack( cortisol tank=insulin tank)
4 Skins glows red hot
So I've read that Peat thinks aging is not necessarily programmed into our bodies - it just happens that regeneration does not happen quickly enough and the system disintegrates. There is no hard 'clock' ticking and then triggering 'destruction'.
I think either case would make sense from an evolutionary perspective?
If an organism would be allowed to live indefinitely, then that would lead to competition with the offspring. And in a competitive environment (i.e. one in which the species is not an apex predator, has limited resources, etc.) it makes sense to strive to evolve and prioritise the offspring at some point.
Even if it's not programmed there is simply not enough incentive to maintain regeneration - even though logically it would seem it should be quite easy - you supply the energy and you get indefinite lifespan. It's aging that's a bit illogical (until you consider the evolutionary pressures).
However, it looks like both of these conditions do not apply to us anymore. We are the apex predator and we do have enough resources. It seems that aging does not necessarily serve it's function very well under these conditions (at least if you look at it from the biological perspective, not e.g. spiritual in which you may need to have an end as being, or 'renewal' at some point).
Do you agree with Peat? Do you think there are possible Peaty interventions beyond diet/lifestyle/supplements that can extend lifespan? E.g. if you theoretically had unlimited capital and scientists at your disposal, would you attempt some sort of a research programme based on Peat principles? (I'm not trying to steal anybody's biotech startup ideas here, I swear)
I think the topic has been discussed previously in general, but perhaps not in the same form.
What does your CRON-o-meter look like? How much (overall) of all the minerals? Protein? What's the PRAL score? Would it be the same with MgCl and KCl?Acidosis is what ages you.
Starting around 23-25 the kidneys cannot create enough Bicarbonate to deal with modern Diets Heavily Consuming Animal Proteins.
Well documented on @Amazoniac Post here.
"The Primary Sources Of Acidity In The Diet Are Sulfur-containing AAs, Salt, And Phosphoric Acid"
- Acidosis: An Old Idea Validated by New Research (the author appears to be credible, you can tell because he's wearing a tie and has his arms crossed) "The idea that “being too acid” contributes to disease susceptibility, especially cancer, has been around for a long time in the...raypeatforum.com
Acidosis-->Cortisol-->Wrecking Ball
"
Acid-base balance in the body influences adrenal hormone production of cortisol. When bicarbonate [HCO3- levels are low, the kidneys upregulate glutaminase activity and trigger cortisol production [35-37]." "Dietary induction of acidosis increases serum cortisol concentrations [38]."
"Cortisol activates the tryptophan metabolism pathway which is carried out by rate-limiting enzymes of tryptophan catabolism, 2,3-dioxygenase (TDO) and indoleamine 2,3-dioxygenase (IDO). Cortisol directly stimulates TDO activation and may augment IDO activity indirectly through inflammatory cytokine signaling such as interferon gamma [49,50]. Excessive or chronic cortisol production acquired from a ‘Western’ dietary lifestyle could play a role in augmenting the tryptophan metabolism pathway and drive downstream molecular events that promote carcinogenesis."
"Upregulated cortisol bioactivity driven by diet-induced acidosis may be a factor in metabolic syndrome by promoting insulin resistance. Chronic hyperglucocorticoidism upregulates visceral obesity while reducing insulin sensitivity mainly in visceral adipocytes which appear to be more responsive to cortisol than subcutaneous adipocytes due to higher expression levels of glucocorticoid receptors [58,59]."
"Acidosis associated insulin resistance through cortisol activity may result in compensatory pancreatic insulin secretion and higher levels of circulating insulin in the serum, a condition known as hyperinsulinemia." As Travisord would say: [sick]"
--------------------------------------------------------------------------------------------------------------------------------------------------------------------------
I supplement Magnesium and Potassium Citrates on 1: 4.8 ratio. These alkalinze the cells and the citrate is converted into bicarbonate almost entirely.
"HCO3- levels are low, the kidneys upregulate glutaminase activity and trigger cortisol production [35-37]."
1 Hair volume trippled(cortsiol tank)
2 Testosterone Went to the moon(cortisol tank)
3 Have an 8 pack( cortisol tank=insulin tank)
4 Skins glows red hot
Hey there,So I've read that Peat thinks aging is not necessarily programmed into our bodies - it just happens that regeneration does not happen quickly enough and the system disintegrates. There is no hard 'clock' ticking and then triggering 'destruction'.
I think either case would make sense from an evolutionary perspective?
If an organism would be allowed to live indefinitely, then that would lead to competition with the offspring. And in a competitive environment (i.e. one in which the species is not an apex predator, has limited resources, etc.) it makes sense to strive to evolve and prioritise the offspring at some point.
Even if it's not programmed there is simply not enough incentive to maintain regeneration - even though logically it would seem it should be quite easy - you supply the energy and you get indefinite lifespan. It's aging that's a bit illogical (until you consider the evolutionary pressures).
However, it looks like both of these conditions do not apply to us anymore. We are the apex predator and we do have enough resources. It seems that aging does not necessarily serve it's function very well under these conditions (at least if you look at it from the biological perspective, not e.g. spiritual in which you may need to have an end as being, or 'renewal' at some point).
Do you agree with Peat? Do you think there are possible Peaty interventions beyond diet/lifestyle/supplements that can extend lifespan? E.g. if you theoretically had unlimited capital and scientists at your disposal, would you attempt some sort of a research programme based on Peat principles? (I'm not trying to steal anybody's biotech startup ideas here, I swear)
I think the topic has been discussed previously in general, but perhaps not in the same form.
I supplement Magnesium and Potassium Citrates on 1: 4.8 ratio. These alkalinze the cells and the citrate is converted into bicarbonate almost entirely.
"HCO3- levels are low, the kidneys upregulate glutaminase activity and trigger cortisol production [35-37]."
1 Hair volume trippled(cortsiol tank)
2 Testosterone Went to the moon(cortisol tank)
3 Have an 8 pack( cortisol tank=insulin tank)
4 Skins glows red hot
I guess soon we'll all be getting spanked; either by him (sky-daddy) or....him (molten core-daddy). Either way I hope ashera will be there, she's got it goin onNo spanking for you. You're on your own.