pufa

  1. haidut

    PUFA metabolites may drive bacterial infections and their resistance to antibiotics

    The study below demonstrates yet again that there is hardly an aspect of human health that PUFA does not influence in a detrimental manner, even seemingly non-metabolic aspects such as bacterial infections. As it turns out, most bacteria express the enzyme family known as lipoxygenases (LOX) and...
  2. haidut

    DHT / Progesterone / aspirin treat, cortisol ineffective, PUFA promotes prostate cancer

    A great study, albeit in-vitro, that once again throws into doubt the entire hypothesis behind prostate cancer. First, it proves the key role of PUFA in the genesis and progression of prostate cancer by demonstrating that inhibitors of the COX enzyme (responsible for synthesizing prostaglandins...
  3. Lewis Acid

    Dr. Chris Knobbe - 'Diseases of Civilization: Are Seed Oil Excesses the Unifying Mechanism?'

    Nothing new for this group - nice to see more recognition of the PUFA topic; a decent presentation as well. Dr. Chris Knobbe is an ophthalmologist and Associate Clinical Professor Emeritus, formerly of the University of Texas Southwestern Medical Center, in Dallas, Texas. He is also the...
  4. Hans

    How to lose fat safely while Peating

    This is a frequent topic on the forum. What about fat loss and fatty acid oxidation, glucuronidation, cortisol, thyroid, etc? All are discussed in the article. How to lose fat safely while Peating
  5. metabolizm

    Is Google pro-PUFA?

    I decided to type "polyunsaturated fat" into Google today, and literally every link on the first page of the search results (including PubMed studies) was decidedly pro-PUFA and anti-SFA. It's not until somewhere down on page two that we see something else: an article from Harpers Bazaar...
  6. haidut

    Glucocorticoids may increase inflammation in the long run

    Glucocorticoids (both bioidentical and synthetic) are some of the most widely used drugs in the clinical setting, as well as in outpatient treatment for all sorts of ailments - i.e. autoimmune conditions, joint pain, post-operative inflammation, asthma, and even infectious diseases such as...
  7. haidut

    PUFA promote torpor / hibernation, decrease lifespan

    Not many studies on this topic, but here is one that will hopefully satisfy my critics who keep complaining that there is no evidence for the anti-metabolic, pro-hibernation effects of PUFA. Apparently, PUFA is sought after by hibernating animals (but even they consume it within very tightly...
  8. haidut

    PUFA are potent immunosuppresive agents

    Just a quick post for all those PUFA/fish-oil lovers who keep sending me hate-mail about the "incredibly beneficial" omega-3, and even omega-6 (e.g. some athletes/bodybuilders tout arachidonic acid as a natural "anabolic agent"). As the study below discusses, all PUFA, but especially omega-3...
  9. haidut

    Blocking PUFA/prostaglandins restores metabolism and reverses brain aging

    The bad news for PUFA has been accumulating for decades, yet public health authorities continue to claim that type of fat is "essential". Whatever indirect admissions of the pathological role of PUFA in both chronic and acute/infectious diseases is given to the public, is usually confined to the...
  10. haidut

    Endotoxin (LPS) as a cause of systemic inflammation seen in obesity

    Yet another study implicating the great villain of systemic health - endotoxin / LPS. It is well-known that most people with obesity have high levels of inflammatory biomarkers both in their tissues and bloodstream. The study below demonstrates that the inflammation seen in adipose tissue of...
  11. haidut

    Even "non-carcinogenic" estrogens can cause cancer

    I know, the title is a "paradox", but this is truly what the article discusses. By now, we already know that the word "paradox" in science is just a euphemism for idotism and/or fraud. Apparently, mainstream medicine has managed to convinced the public somehow that there are carcinogenic and...
  12. J

    Wild Salmon Fixed Dry Skin and Improved Digestion

    Been on a very low PUFA and restricted diet (mostly carnivore, but experimented a lot with carbs, no fish) for almost 2 years. I've had dry skin, especially on my knuckles for about 1 and a half years. I had read to eat more fat and so I did. Lamb fat, beef fat, but the more fat I ate, the...
  13. Jam

    Mortality From Coronavirus Disease 2019 Increases With Unsaturated Fat and May Be Reduced by Early Calcium and Albumin Supplementation

    Mortality From Coronavirus Disease 2019 Increases With Unsaturated Fat and May Be Reduced by Early Calcium and Albumin Supplementation What You Need to Know Background and context While most COVID-19 patients clear the infection, some develop severe disease with organ failure. Based on patterns...
  14. DANIEL

    How Margarine and Processed Vegetable Oils Are Made 🤮

  15. haidut

    Stress-driven lipid peroxidation, inflammation re-awakens dormant cancer cells

    Yet another study demonstrating that stress is anything but benign or irrelevant for chronic diseases, especially for cancer. The study below demonstrates that stress-induced increases of epinephrine and norepinephrine results in increased lipolysis and a cascade of pro-carcinogenic downstream...
  16. haidut

    Glycine (and leucine) can treat fatty liver (NAFLD and NASH)

    A great new study that demonstrates the strong protective effects of glycine, alone or in combination with leucine, on preventing/treating various forms of fatty liver disease, as well as the obesity that often accompanies these conditions. One of the strong points of the study is that it also...
  17. haidut

    PUFA is catabolic, SFA is anti-catabolic (anabolic)

    During the early days of anabolic-androgenic steroid (AAS) science, it quickly became apparent that the ability of AAS to preserve and/or increase muscle mass was related to their ability to reduce/block the expression of amino acid catabolic enzymes such as tyrosine aminotransferase (TAT). TAT...
  18. DANIEL

    Anti-Peat Peat Wrong About PUFA?

    Peat's claim about PUFA is arguably his most controversial viewpoint. A lot of the disagreement has to do with Peat basing his perspective on rat studies and then claiming that his findings apply to humans as well. I came across this pro-PUFA article and I was wondering if you guys could share...
  19. Lokzo

    An Interview With Haidut (Georgi Dinkov) About PUFA's

    Here's a snippet of my podcast with @haidut ! Full episode will be live here soon: Boost Your Biology
  20. GorillaHead

    Proposed Theory: Dandruff Is A Skin Biome Imbalance. Ways To Address Proposed

    Today I am going to discuss my struggle with dandruff, everything I have tried, the mechanism perhaps behind one main cause and a way to address it. Of all the ailments I have dealt with (and believe me I have dealt with so many) Dandruff was one of the most stubborn issues I seemed to suffer...
Top