lps

  1. haidut

    Niacinamide May Improve Symptoms Of ALS

    Just over a week ago I posted a thread on ALS being linked to increased fatty acid oxidation (FAO) and as such a decreased glucose availability/oxidation. ALS Tied To Increased Fat Oxidation (FAO), Increasing Glucose May Treat It Now, the study below further corroborates this FAO-disease...
    • haidut
    • Thread
    • als endotoxin fao lps microbiome niacinamide vitamin b3
    • Replies: 9
    • Forum: Scientific Studies
  2. haidut

    MS Tied To Glucose Deficiency Due To Endotoxin And Fat, Extra Glucose May Treat It

    Just a few days ago I posted the groundbreaking study on metabolic derangement in ALS - i.e. it is a diseased characterized by increased FAO, which wastes glucose. Simply increasing dietary glucose was able to greatly restrain the pathology...
    • haidut
    • Thread
    • ceramides fao fatty acid oxidation glucose insulin resistance lps mitochondria mitochondrial function ms multiple sclerosis randle cycle tlr tlr4
    • Replies: 48
    • Forum: Scientific Studies
  3. P

    Prebiotic And Anti Endotoxin Effects Of Dietary Calcium

    Calcium supplementation modulates gut microbiota in a prebiotic manner in dietary obese mice. - PubMed - NCBI Could the beneficial effects of dietary calcium on obesity and diabetes control be mediated by changes in intestinal microbiota and integrity? - PubMed - NCBI
  4. haidut

    Endotoxin (LPS) Linked To Lower Survival In Cancer

    Another study about endotoxin, this time linking higher sensitivity to endotoxin to lower survival chance for people with lymphoma. While the study below looked at only one cancer, there are multiple studies with other cancer that have found similar link. Endotoxin and cancer go hand in hand...
    • haidut
    • Thread
    • cancer cause endotoxin exacerbate lps lymphoma mortality tlr tlr4
    • Replies: 2
    • Forum: Scientific Studies
  5. haidut

    Blocking Endotoxin (LPS) May Reverse/cure Diabetes Type I

    Yet another study demonstrating the key role of endotoxin in the pathology of perhaps the most widespread chronic disease - diabetes. The study below discovered that the proliferation of the insulin-producing beta-cells in the pancreas is controlled almost entirely by the TLR4/TLR2 receptor...
    • haidut
    • Thread
    • beta-cells cause diabetes endotoxin inflammation insulin lps pancreas tlr tlr2 tlr4
    • Replies: 5
    • Forum: Scientific Studies
  6. haidut

    Endotoxin (LPS) May Cause Depression / Anhedonia

    As many readers know, anhedonia is one of the most pernicious aspects of clinical depression. It is present in other mental health conditions but is most pronounced and severe in clinical unipolar depression. It is also especially resistant to treatment and many doctors simply accept it as...
    • haidut
    • Thread
    • anhedonia cause depression endotoxin inflammation lps tlr tlr4
    • Replies: 31
    • Forum: Scientific Studies
  7. haidut

    Endotoxin (LPS) May Be A Major Cause Of Preterm Births

    As many readers have probably heard, rates of preterm births due to a variety of maternal conditions including (pre)eclampsia has been steadily increasing since the 1980s. The official version is that the cause is unknown despite older studies proving definitively that progesterone deficiency...
    • haidut
    • Thread
    • cause drive endotoxin exacerbate il-10 il-6 inflammation lps preemie pregnancy preterm birth tlr4
    • Replies: 0
    • Forum: Scientific Studies
  8. haidut

    All Gut Bacteria Dangerous, Its Endotoxin Drives Liver Cancer; Antibiotics Cure

    As Peat has written many times, there is truly no such thing as “beneficial” gut bacteria as long as they are capable of producing endotoxin (LPS). And since most bacterial species known to colonize the gut can produce LPS when exposed to undigested food or mechanical stimulation (stretching or...
    • haidut
    • Thread
    • antibiotics bacteria cancer colon cure endotoxin gut hcc hepatocellular carcinoma inflammation liver lps microbiome probiotics tlr4
    • Replies: 147
    • Forum: Scientific Studies
  9. haidut

    Damaged Mitochondria And Endotoxin (LPS) Drive Chronic Inflammation

    Chronic, low-grade inflammation has now been recognized as the main cause behind a number of chronic degenerative conditions including CVD, diabetes, cancer, Alzheimer, Parkinson, etc. Mainstream medicine claims that the cause of this chronic low-grade inflammatory reaction is unknown, despite...
    • haidut
    • Thread
    • choline chronic damage endotoxin inflammation lps mitochondria mitophagy stress tlr4
    • Replies: 5
    • Forum: Scientific Studies
  10. haidut

    A Lab Test For Endotoxin Exposure, And Its Role In HIV/AIDS

    While I was researching some other topics related to the article on statins and TLR4 that I posted last week, I stumbled upon a biomarker called "soluble CD14" or sCD14 for short. CD14 - Wikipedia As it turns out, sCD14 is a biomarker for systemic endotoxin load. The importance of soluble CD14...
    • haidut
    • Thread
    • biomarker cd14 endotoxin exposure inflammation load lps scd14 soluble cd14 tlr4
    • Replies: 9
    • Forum: Scientific Studies
  11. haidut

    Endotoxin Causes Cachexia In Cancer; How Statin Drugs Really Work

    The title of the post is a bit strange but it is pretty much what the study below found. Just like the SSRI drugs, the mechanism of action of statins is (officially) not really known. The official version for the antidepressant effects of SSRI drugs was that they increase intracellular levels of...
    • haidut
    • Thread
    • atorvastatin block brown fat cachexia cancer endotoxin lipitor lps prevent statin statins tlr4 tumor wasting
    • Replies: 8
    • Forum: Scientific Studies
  12. haidut

    Pregnenolone Is A Potent (functional) Endotoxin (TLR4) Antagonist

    It seems that pregnenolone is finally starting to look exciting to the medical industry. In addition for its intensive studies for a variety of mental issues, now studies are coming out demonstrating its endotoxin (LPS) antagonism effects. As most forum users know, endotoxin exerts its effects...
    • haidut
    • Thread
    • alcoholism allopregnanolone alzheimer's antagonist cvd depression endotoxin epilepsy immune system inflammation lps ms multiple sclerosis pregnenolone ptsd schizophrenia sepsis tlr4 tnf
    • Replies: 10
    • Forum: Scientific Studies
  13. haidut

    Endotoxin (and Baby Formula) May Be The Cause Of IBD And Brain Damage

    It is a well-publicized fact that people with inflammatory bowel disease (IBD) such as Crohn's and ulcerative colitis (UC) struggle with severe cognitive and mood issues. They are also at a much greater risk of developing dementia than the general population, and at a much younger age too...
    • haidut
    • Thread
    • baby formula brain damage cognitive impairment crohn's endotoxin formula ibd inflammatory bowel disease lps mental illness nec necrotizing enterocolitis stress tlr4 uc ulcerative colitis
    • Replies: 29
    • Forum: Scientific Studies
  14. ecstatichamster

    LPS (endotoxins) Kills Pain

    https://www.sciencedirect.com/science/article/pii/0006899394919089 Abstract Activation of the immune system in response to either infection or lipopolysaccharide (LPS) produces neurophysiological, neuroendocrine and behavioral changes. Some of the physiological consequences of LPS are mediated...
  15. haidut

    Soluble Fiber Causes Liver Cancer, Insoluble And Antibiotics Prevent/stop It

    Perhaps one of the most controversial topics in Peat-land is fiber. Over the years he has consistently recommended insoluble fiber, such as found in carrots/mushrooms/bamboo, while recommending explicitly against soluble fiber such as pectin and other fermentable starches. I think in one of his...
    • haidut
    • Thread
    • cancer cause dysbiosis endotoxin fos fructooligosaccharadise guar gum hcc inulin liver cancer lps microbiome pectin soluble fiber
    • Replies: 205
    • Forum: Scientific Studies
  16. haidut

    Saturated Fat (palmitate) Does NOT Activate TLR4

    We must have had hundreds of discussions on this topic on the forum. Some forum users strongly believe that saturated fat (SFA) increases inflammation by binding to and activating the endotoxin (LPS) receptor TLR4. Among all SFA, palmitate is the one most commonly blamed and has been...
    • haidut
    • Thread
    • disease endotoxin inflammation jnk lps obesity palmitate palmitic acid saturated fat sfa tlr4 vindicated
    • Replies: 28
    • Forum: Scientific Studies
  17. haidut

    The Benefits Of Fasting Are Due To Lowering Endotoxin (LPS), Not Less Calories

    As many of you know, the argument for/against fasting has been raging on the forum for several years at this point. While Ray has spoken several times favorably about potentially skipping a meal or two, he has repeatedly said that chronic fasting is not something he recommends due to its...
    • haidut
    • Thread
    • antagonist benefits caloric restriction cr diabetes endotoxin fasting inflammation lps microbiome obesity tlr4
    • Replies: 39
    • Forum: Scientific Studies
  18. haidut

    Endotoxin Causes (liver) Steatosis, Insulin Resistance And Atherosclerosis

    I know this study was in hepatitis C patients only, but there is nothing about Hep C that would invalidate this finding in the general population too. Quite a few people on the forum reported that when they tried to talk to their doctor about endotoxin and its possible role in their health...
    • haidut
    • Thread
    • atherosclerosis cvd endotoxemia endotoxin hepatitis inflammation insulin resistance liver lps steatosis tlr4
    • Replies: 16
    • Forum: Scientific Studies
  19. haidut

    Sterilizing The Gut Restores Insulin Sensitivity By Reducing Fatty Acid Oxidation

    I am posting this study just as an example of how important the role of endotoxin is in insulin resistance and diabetes. Similarly to the human study with aspirin, sterilizing the gut with antibiotics did not reduce the weight in the obese subjects (in this case mice). So, obesity may be a less...
    • haidut
    • Thread
    • antibiotics bacteria beta oxidation colon diabetes endotoxin fatty acid oxidation ffa gut insulin resistance insulin sensitivity lps microbiome obesity sterile sterilizing
    • Replies: 71
    • Forum: Scientific Studies
  20. haidut

    Pulmonary Fibrosis May Be Caused By Endotoxin (LPS)

    Ray spoken and written at length about endotoxin (LPS) and its role in virtually all chronic conditions. Mianstream medicine vehemently denies that LPS is an issue, except possibly for people with liver disease. But in thoses cases, the claim is that endotoxin may cause fever and diarrhea but...
    • haidut
    • Thread
    • endotoxin fibrosis inflammation lps pulmonary fibrosis scleroderma systemic sclerosis tlr4
    • Replies: 9
    • Forum: Scientific Studies
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