• tca300: I understand this is off topic from what you typically teach, but I was wondering if you have run across any information or learned on your own, things that help people grieve over lost loved ones, and or fear of losing others to death? Thank you!

    Ray Peat: It activates the “helplessness” reactions in the body, stress weakening your own life, and I think it can help to get out of that if you think of your life as a continuation of theirs—the same life, though with fewer bodies.

    Rest in Paradise, Raymond Peat  October 12, 1936 - November 24 2022

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beta cells

  1. haidut

    Anti-adrenaline Drugs Like Clonidine May Prevent Diabetes Type I

    Peat mentioned a few times that the pancreatic damage seen in type I diabetes is caused by prolonged exposure to PUFA, as unsaturated fats are toxic to the insulin-producing beta cells in that organ. Many of the cases of new onset diabetes I occur after a period of extreme exhaustion and/or...
  2. P

    Low Dose Doxycycline Decreases Systemic Inflammation And Improves Glycemic Control, Lipid Profiles,

    Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in <i>db/db</i> mice Low dose doxycycline decreases systemic inflammation and improves glycemic control, lipid profiles, and islet morphology and function in...
  3. P

    Diabetogenic Impact Of Long-chain Omega-3 Fatty Acids On Pancreatic Beta-cell Function And The Regul

    Diabetogenic impact of long-chain omega-3 fatty acids on pancreatic beta-cell function and the regulation of endogenous glucose production. - PubMed - NCBI Abstract In healthy individuals, peripheral insulin resistance evoked by dietary saturated lipid can be accompanied by increased insulin...
  4. P

    Bone Regulates Glucose Metabolism As An Endocrine Organ Through Osteocalcin

    Bone Regulates Glucose Metabolism as an Endocrine Organ through Osteocalcin. - PubMed - NCBI Skeleton was considered as a dynamic connective tissue, which was essential for mobility, calcium homeostasis, and hematopoietic niche. However more and more evidences indicate that skeleton works not...
  5. Giraffe

    Repair Of Pancreatic Beta-Cells

    Repair of Pancreatic β-Cells: A Relevant Phenomenon in EarlyIDDM Most studies dealing with the pathogenesis of IDDM have emphasized the immune assault against β-cells. In this perspective, we review the data that suggest that the β-cell destruction of IDDM depends on a balance between β-cell...
  6. P

    Biotin Suppresses Food Intake

    Biotin augments acetyl CoA carboxylase 2 gene expression in the hypothalamus, leading to the suppression of food intake in mice. - PubMed - NCBI It is known that biotin prevents the development of diabetes by increasing the functions of pancreatic beta-cells and improving insulin sensitivity...
  7. haidut

    Pregnenolone For Blood Sugar Control

    It was recently discovered that the so-called TRM3 "receptors" in the pancreatic beta cells can be activated by pregnenolone sulfate (PS) at relatively low concentrations and result in insulin release. This makes pregnenolone a potential tool for keeping blood sugar levels normal and can also...
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