I have anhedonia and depersonalization from taking SSRIs and tricyclics. The only thing to ever give a window was coming off amitriptyline abruptly, which might have temporarily upregulated some receptors like serotonin or histamine. Maybe 5ht2a and 5ht2c.
I see that others get the same effect from cyproheptadine rebound and I'm wondering if you took an ultra low microdose (probably under a miligram) if this could permanently upregulate the receptors?
I can't stand cyproheptadine at regular doses because it makes me feel even more unconscious.
Sorry to rant now but I am sick and tired of trying to work this ***t out! I just don't understand how you can take an antidepressant and then your receptors are permanently desensitized for years and years.
Will never get my head around it.
I see that others get the same effect from cyproheptadine rebound and I'm wondering if you took an ultra low microdose (probably under a miligram) if this could permanently upregulate the receptors?
I can't stand cyproheptadine at regular doses because it makes me feel even more unconscious.
Sorry to rant now but I am sick and tired of trying to work this ***t out! I just don't understand how you can take an antidepressant and then your receptors are permanently desensitized for years and years.
Will never get my head around it.