pain

  1. P

    Effect Of Vitamin D Supplementation On Pain: A Systematic Review And Meta-analysis

    Effect of Vitamin D Supplementation on Pain: A Systematic Review and Meta-analysis. - PubMed - NCBI CONCLUSION: A significantly greater mean decrease in pain score (primary outcome) was observed with vitamin D supplementation compared with placebo in people with chronic pain. These results...
  2. Giraffe

    Analgesic Effect Of Methylene Blue

    I came accross an article written by Paul Ehrlich and Arthur Leppmann called "Über schmerzstillende Wirkung des Methylenblau." published in 1890 in the Deutsche Medizinische Wochenschrift. This was a couple of years before Aspirin came on the market. The researchers tested methylene blue on...
  3. haidut

    Emotional Response To Pain Is Driven By Serotonin And Prostaglandins

    I posted previously on how serotonin is required for the formation of traumatic memories. This process plays a major role in disorders like depression, PTSD, chronic anxiety and even schizophrenia. Serotonin Is Involved In The Formation Of Traumatic Memories This study shows that the activation...
  4. L

    Complex Regional Pain Syndrome

    Anyone know anything about this condition and how to treat using Ray Peat friendly suggestions? I do not have enough comprehension or knowledge to attempt to help her but I feel for her and she is a bit panicked. A friend has recently been diagnosed with this condition and she is suffering. MD...
  5. haidut

    Theanine As A Novel Painkiller

    The placebo effect has been confirmed in many studies, and there have even been calls to change its name since the current one is at best a misnomer - i.e. we seem to have a much more fundamental and physical connection with our environment than the presence or lack of chemicals/drugs can...
  6. haidut

    Opioids Increase Pain Through Endotoxin Receptor, Minocycline Reverses The Effect

    Most people here know Peat's opinion about opioids due to their effects on histamine, estrogen, and promoting tissue growth. A few weeks ago I posted a link in regards to the so-called "endotoxin receptor" known as TLR4, and how opioids are the main class of substances that activate that...
  7. Pointless

    T3 And Neuropathic Pain

    I bought some T3 and T4 from USA Peptide in separate bottles. I take the T3 3 times a day, and with the last dose, I take twice as much T4 along with it. They are both in 200 mcg/mL, which would be an approximate dose of 10 mcg/drop. I try to eat it with food to prolong the spike in...
  8. haidut

    Itching May Be Driven By Serotonin

    I have always wondered about this phenomenon and why it is that people with chronic conditions or depression seem to have a problem with excessive itching. It turns out that itching is closely related to pain and as such the release of serotonin. I already posted about the relationship between...
  9. S

    Pain Causes Relapse In A Model Of Multiple Sclerosis

    A pain-mediated neural signal induces relapse in murine autoimmune encephalomyelitis, a multiple sclerosis model
  10. haidut

    Babies Feel Pain Just Like Adults

    Ray is often critical of the tendency of modern science to consider living organisms in a hierarchy of "consciousness", with organisms lower in the hierarchy considered to be "less than fully alive" and certainly not able to experience the full gamut of what humans are capable of. Here is a...
  11. haidut

    Why Ray Peat May Be Advising Against (strong) Spices

    Ray has written on the topic of de-ennervation and how it negatively affects the tissues where nerves die off or have reduced communication efficiency. He wrote that some spices, especially capsaicin, are known to cause de-ennervation and he tries to avoid those. This recent study seems to...
  12. R

    Aspirin - Causing "pain"!

    Yes, aspirin seems to reveal some kind of pain. It's not actually a problem, no severe pain, but I wonder what it's all about. I have mentioned in another thread that I have problems on the left side of my body, and now when I take aspirin I "feel" stuff going on in my hip, shoulder and along...
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