I decided to try 2mg of Naltrexone yesterday... Yes, I know, this is NOT a low beginner dosage.
Wow, it has completely NUMBED my pleasure response to the following:
-Food literally has no appeal.
-Likes on IG.
Everything about my reward...
I posted a few threads in the past about addiction, and especially alcohol addiction being driven by high cortisol and low dopamine. This new study adds more pieces to the puzzle by implicating endotoxin in that process as well. Just as importantly, the study found that the desire to drink...
Effects of morphine dependence and withdrawal on levels of neurosteroids in rat brain. - PubMed - NCBI
It's a rat study but I think the results are applicable to humans.
"The chronic morphine administration (ip) resulted in a marked decrease in the brain concentrations of pregnenolone (PREG)...
Chorionic morphine, naltrexone and pentoxifylline effect on hypophyso-gonadal hormones of male rats. - PubMed - NCBI
Knowledge about harmful effects of morphine on hormone secretion seems to be necessary. The aim of the present study was to evaluate the effect of...
I have been researching this lately, since I have always wondered why salt is thermogenic. It looks like one of the main reasons is that salt acts like a functional opioid "receptor" antagonist, very similar to naltrexone. As you probably know, all opioid agonists (alcohol, morphine...
With the caveat that this is not a medical recommendation here is my experience with some drugs looked favorably upon by Peat. I got mine from Europe where you dont need prescription for these drugs.
Cyproheptadine: for me the optimal dose is 4mg at night before going to bed. Takin more makes me...
I have been suffering from anhedonia (loss of pleasure, no excitement, detachment, etc) I was wondering if bromocriptine or LDN would be useful to experiment with? Any opinions, experiences?
Would like to get a thread going about Low Dose Naltrexone. Seems like a winner after researching it some today. Please report your experiences with it, good, or bad. What do you know about it, etc....