mood

  1. TMCMac

    AlloP is helping a lot with anxiety and mood! Can I replicate this without it? Would it be sustainable long term?

    I have struggled with a lot of anxiety and mood lately as I work 70 hours and I got Georgis AlloP and its helped a lot with mood and Ive noticed it increases my wanting to socialize it comes so much more natural. I take 4-8mg allop for the past week. I also pair it with metergoline 4mg. I...
    • TMCMac
    • Thread
    • allopregnanolone caffeine isolation metergoline mood socializing
    • Replies: 19
    • Forum: Testimonials
  2. haidut

    Dietary sugar can treat chronic depression

    Not much to comment on here, except to point out that the sugar "addiction" in depressed people has been recognized by medicine for at least 50 years and has always been treated as a co-morbidity of the depressed state, also in need of treatment. Doctors have been advising depressed patients to...
    • haidut
    • Thread
    • depression dopamine mental health mood reward sucrose sugar
    • Replies: 16
    • Forum: Scientific Studies
  3. TMCMac

    Alternatives to Nicotine / Lowering DHT to 3adiol

    Anyone know of other substances or ways to lower the conversion of DHT to 3adiol other than nicotine? I suspect this is one of my issues potentially after gaining a lot of weight so looking for ways to improve this as I work on lowering body fat. Nicotine helps give me that calm masculine...
    • TMCMac
    • Thread
    • 3adiol 5ar androgens calm dht dopamine mood nicotine
    • Replies: 1
    • Forum: Male Issues
  4. haidut

    Vitamin D likely effective as an antidepressant

    That is the simple conclusion of the largest meta-study to date. Namely, vitamin D in doses above 2,000 IU daily has antidepressant effect when used as monotherapy. The antidepressant effects of vitamin D when used in combination with pharma antidepressant drugs is already well-established, so...
    • haidut
    • Thread
    • antidepressant cholecalciferol depression mental illness monotherapy mood vitamin d
    • Replies: 2
    • Forum: Scientific Studies
  5. JamesGatz

    Is there a significant effect on the metabolism just by being around specific people ?

    I've been noticing a couple of things lately - I notice that before peating when my health was bad - I really enjoyed being around metabolically healthy people and especially that is true today - It made me feel very comfortable - as we know from this forum anything can be anything so there must...
  6. Hans

    The Dopamine Dream Team Stack

    I've been looking far and wide and experimenting all over the place with different compounds to get see what gives me the best effects. On my quest of understanding energy metabolism and neurotransmitters, it became obvious that the two are interlinked. So I designed a stack around that. Have a...
  7. Lokzo

    Low Dose Naltrexone For Anhedonia/PSSD - WATCH OUT!

    Hey guys, I decided to try 2mg of Naltrexone yesterday... Yes, I know, this is NOT a low beginner dosage. Wow, it has completely NUMBED my pleasure response to the following: -Music. -Exercise high. -Sex. -Sweet foods. -Food literally has no appeal. -Likes on IG. Everything about my reward...
    • Lokzo
    • Thread
    • anhedonia mood naltrexone pssd
    • Replies: 5
    • Forum: Experiments
  8. haidut

    A Proposed Anabolic Mechanism Of Tribulus Terrestris (TT)

    Some people on the forum like @Wagner83 myself and a few others have tried the infamous herb TT with the hope of raising androgens and improving body composition. Despite Wikipedia bashing TT and raising doubts about its effectiveness, there is plenty of evidence from human trials shows the herb...
    • haidut
    • Thread
    • anabolic antagonism antagonist anticatabolic antidepressant brain cognition cortisol crh diosgenin mood protodioscin tigogenin tribulus terrestris
    • Replies: 457
    • Forum: Scientific Studies
  9. haidut

    Allopregnanolone May Soon Be Approved As A Fast-acting Antidepressant

    The patents on most SSRI drugs have either expired or are close to expiration. Lately, there have also been a number of high profile cases obtaining favorable court outcomes by blaming SSRI drugs for a host of human criminal behaviors or adverse health events. As such, Big Pharma is desperate to...
    • haidut
    • Thread
    • 5a-dhp allopregnanolone antidepressant approval brexanolone fast-acting fda gaba mental health mental illness mood progesterone steroid
    • Replies: 67
    • Forum: Scientific Studies
  10. haidut

    Hepatitis B Vaccine In Infants Linked To Subsequent ADHD

    The study only looked at the older version of the HepB vaccine, which contained thimerosal. So, it would be interesting to see a study on the newer vaccine, which uses "only" aluminium as adjuvant. I bet the effects won't be much different as aluminium is just as toxic to the nervous system. A...
    • haidut
    • Thread
    • adhd adjuvant disorder hepatitis b mental mood thimerosal vaccines
    • Replies: 4
    • Forum: Scientific Studies
  11. haidut

    High Lactate May Be The Cause Of Major Psychiatric Disorders

    The study itself has a misleading title because there are quite a few situations that can result in lower brain pH (and thus high acidity). High levels of CO2 can also cause low brain pH levels, but as I posted in a few other studies drugs that raise CO2 levels can actually treat mental disease...
    • haidut
    • Thread
    • bipolar disorder cause depression disorder elevated high lactate lactic acid manic mental mood psychosis schizophrenia
    • Replies: 6
    • Forum: Scientific Studies
  12. haidut

    High Cortisol / Testosterone Ratio As A Likely Cause Of PTSD

    As the study below says the role of cortisol (C) in mood disorders has been known for more than 30 years. Cortisol's role in depression, schizophrenia, bipolar, and eating disorders is well known even in mainstream psychiatry and many of the new drugs in pharma pipeline are aimed at suppressing...
    • haidut
    • Thread
    • cortisol disorder hypothyroidism mood ptsd ratio stress testosterone
    • Replies: 18
    • Forum: Scientific Studies
  13. haidut

    Pregnenolone Activates The Glycine Receptor

    This mechanism of pregnenolone is one of the proposed methods through which it enhances neurogenesis, memory, mood and even motor function. Low doses pregnenolon improve sleep quality and are even mildly sedating, which may also be due to the activation of the glycine receptor. Subunit-specific...
    • haidut
    • Thread
    • agonist cognition glycine memory mood pregnenolone receptor relaxation sleep
    • Replies: 3
    • Forum: Scientific Studies
  14. haidut

    Caffeine And Aspirin Improve Both Mood And Performance

    Human study with low dose of caffeine and moderate dose of aspirin. http://www.ncbi.nlm.nih.gov/pubmed/3680601 "...We observed that caffeine (64 mg), when added to aspirin (800 mg), significantly improves vigilance performance and increases self-reported efficiency when compared with either...
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