inhibit

  1. cs3000

    High Acetylcholine = learned helplessness, depression - What are good ways to lower acetylcholine or increase acetylcholinesterase activity?

    Ray peat has spoken about the negatives of acetylcholine relating to stress and learning Acetylcholine is an excitotoxic neurotransmitter Acetylcholine likely raises serotonin in the brain (preferentially inhibits MAO-A in the brain) https://pubmed.ncbi.nlm.nih.gov/19025057/ AChE inhibitors...
    • cs3000
    • Thread
    • acetylcholine acetylcholinesterase depression inhibit learned helplessness lower acetylcholine reduce
    • Replies: 13
    • Forum: Ask For Help or Advice
  2. haidut

    High-salt Diet Strongly Inhibits Cancer Growth

    I am posting this study mostly as a response to the hostile exchanges I have had with doctors over what they claimed was "irresponsible" promotion of high salt intake. While these discussions mostly revolved around CVD, I also made claims that increased sodium intake would be protective for...
    • haidut
    • Thread
    • cancer diet growth high-salt inhibit salt sodium tumor
    • Replies: 16
    • Forum: Scientific Studies
  3. haidut

    Aspirin May Treat Brain Aneurysms

    Another huge win for aspirin, not only because of the condition's lethality, but because there is currently no treatment for it. While the study did not last long enough to make such claims, given the potent inhibitory effect on aneurysm growth I would not be surprised if aspirin actually makes...
    • haidut
    • Thread
    • aneurysm aspirin brain growth inhibit intracranial prevent reduce rupture slow treat
    • Replies: 1
    • Forum: Scientific Studies
  4. haidut

    Inhibiting Fatty Acid Synthesis (FAS) Dramatically Improves Sepsis Survival Rate

    Yet another study that points the finger straight at fat as a key factor in one of the most common causes of inpatient hospital mortality - sepsis. Sepsis is currently considered to be a condition of infectious (bacterial) etiology, driven by endotoxin. However, in light of the new findings it...
    • haidut
    • Thread
    • endotoxin energy fao fas fasn fatty acid oxidation fatty acid synthase infection inhibit inhibitor randle cycle sepsis tlr tlr4
    • Replies: 6
    • Forum: Scientific Studies
  5. haidut

    Consciousness Is Quantum, Can Be Modulated With Specific Chemicals

    Many readers are likely familiar with the theories of Roger Penrose on the topics of consciousness and how it relates to physics and even cosmology. He is perhaps the most vocal proponent of "quantum consciousness" theories, including his own theory known as "orchestrated objective reduction"...
    • haidut
    • Thread
    • anesthetic consciousness inhibit microtubules nuclear spin pregnenolone promote quantum entanglement quantum mechanics resonance tubulin xenon
    • Replies: 108
    • Forum: Scientific Studies
  6. haidut

    PUFA Inhibit Progesterone Production And Thus Drive/cause Menopause

    Peat wrote in a few of his articles that menopause is largely driven by a deficiency of progesterone and mentioned several anecdotes of women in their 50s and 60s getting their periods back after supplementing with large doses progesterone. In one of his articles he said that PUFA and estrogen...
    • haidut
    • Thread
    • andropause epa gonads hypogonadism inhibit menopause omega-3 progesterone pufa steroidogenesis steroids synthesis
    • Replies: 7
    • Forum: Scientific Studies
  7. haidut

    Niacinamide May Treat Brain Cancer (glioblastoma)

    Neuroblastoma is one of the most common brain cancers and one of the most lethal ones of all cancers. Senator John McCain is probably the most famous recent victims of this cancer, and others famous cases include Senator Ted Kennedy and one of Joe Biden's son. The latter two died from the cancer...
    • haidut
    • Thread
    • block brain cancer glioblastoma inhibit neuroblastoma neuroglioblastoma niacinamide sirt6 sirtuins tumor vitamin b3
    • Replies: 8
    • Forum: Scientific Studies
  8. haidut

    Yet Another Study Calls For Inhibiting Fat Oxidation As A Treatment For Cancer

    I have posted a number of threads on the role of fatty acid oxidation (FAO) and fatty acid synthase (FAS) in cancer growth and progression. Inhibiting Lipolysis May Treat / Cure Cancer For more than 100 years FAO and FAS were thought of pathways irrelevant for cancer and also as ones that are...
    • haidut
    • Thread
    • cancer cure fatty acid oxidation fatty acid synthesis inhibit inhibitor therapeutic treatment
    • Replies: 17
    • Forum: Scientific Studies
  9. haidut

    Acetaminophen (Tylenol) Decreases Respiration By Changing Cardiolipin Composition

    I posted a few threads recently on the negative effects of acetaminophen (Tylenol) on brain function and steroid response. Acetaminophen (Tylenol) Exposure During Pregnancy Feminizes The Offspring Acetaminophen raises serotonin/adrenaline, aspirin lowers it User @Koveras also posted a thread...
    • haidut
    • Thread
    • acetaminophen cardiolipin composition decrease inhibit levels lower respiration tylenol
    • Replies: 18
    • Forum: Scientific Studies
  10. haidut

    Estrogen Impairs Memory In Women

    There has been some evidence from rodent studies that estrogen and BDNF are antagonistic to each other as animals exposed to estrogen cannot remember very well. BDNF is akin to an anabolic steroid for the brain, and estrogen powerfully impairs its effects, especially in cases of traumatic brain...
    • haidut
    • Thread
    • alzheimer's bdnf dementia estradiol estrogen hrt inhibit memory women
    • Replies: 1
    • Forum: Scientific Studies
  11. haidut

    Famotidine Is A Powerful Anti-serotonin Drug, Can Even Treat Serotonin Syndrome

    I wanted to make this as a separate thread, given how important anti-serotonin chemicals for metabolism and how few of them are available OTC. It looks like our old friend famotidine is a powerful inhibitor of serotonin synthesis in the GI tract, and the mechanism of action is the H2 antagonism...
    • haidut
    • Thread
    • anti-histamine famotidine inhibit inhibitor prevent serotonin serotonin syndrome treatment
    • Replies: 139
    • Forum: Scientific Studies
  12. haidut

    Aspirin Can Slow Brain Aneurysm Growth

    I posted a few studies in the past showing that aspirin actually lowers the risk of deadly bleeding events in the GI and brain - the two most notorious side effects cites against the use of aspirin. The Benefits Of Aspirin Outweigh The Bleeding Risks GI Bleeding Risks Of Aspirin Are Grossly...
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