I was really horrified to read what the initially innocuous sounding eyedrops were likely to be based on: adrenergics, beta blockers and prostaglandins! for starters. And their preservatives.
Precisely SQu, exactly what my research reveals. Disease does not just fall out of the sky. Or you have perfect eyes one month and boom a derelict gene gets turn on and your cornea thins. There needs to be that perfect planetary alignment, where a set of variables come into play and boom a perfect storm.
Contacts are being worn for fashion, why the hell would you want to wear them if you have perfect vision - boogles the mind.
The following is an article as SQu mentioned is on vasoconstrictors. Anyone use murine. Pissing in the eye does the trick.
https://www.reviewofophthalmology.com/article/vasoconstrictors-myths-and-realities
MB is a photosensitiser so you need to be extremely careful if you are thinking of using it for dry eye conditions. This is completely wrong thinking. Let me explain. First, you need to understand that in dry eye condition, it is lack of tear film that coats the cornea that is the problem. When there is a lack of this tear film, the corneal cells are subjected to increased oxidative stress and increased organic peroxides that need to be neutralised. So compared to normal corneas, dry cornea are subjected to increase reactive oxygen species.
Methylene blue is a photosensitizer used to create singlet oxygen when exposed to both oxygen and light. It is used in this regard to make organic peroxides by a Diels-Alder reaction which is spin forbidden with normal atmospheric triplet oxygen.
So methylene blue will create more ROS (just from normal oxygen) to an already overburdened and exhausted corneal tissue that is dealing with ROS. You need to increase the tear film and the tear film needs to be nutrient rich to neutralise the deleterious reactive molecules. You do not want to add my fuel to the fire!!!
Fungal keratitis: Rapid diagnosis using methylene blue stain
I provide the attached file on methylene blue, to caution when experimenting with the eyes. You can experiment on your dog, cat or rabbits eyes but be extremely careful when it comes to your own eyes. If you are wearing contacts, then you have no idea what is breeding on the surface or just below the surface of the cornea. Many people have ulcers and may not even be aware of these. I like to work with biological substances rather than nasty chemicals. Nature is much more clever and sophisticated and industrial chemical. Why even urine offers many beneficial molecules that get flushed down the toilet every day. I would do organic raw milk as milk has loads of beneficial molecules. Autologous serum is excellent for dry eyes has shown to improve tear film and slow breakdown time. It would be expensive to have a dr to do it for you, but if you are game to do your own blood draws, then it is far superior - it is your own biological fluid. You are less likely to reaction to your own body fluids. It is not hard to do, spin it down and take the serum off. Place into tiny vials and freeze. Take out as needed and apply to the cornea. If you know anyone that is expecting a baby, then plead with them to keep the placenta for you. You can cut it up into pieces, freeze and apply on the eye, like a band-aid. It has wonderful healthy properties.
Used in Eye Surgery to Help Damaged Eye Surfaces Heal Faster | AmnioGraft®
The beauty of having your own animals is that you can easily have access to the placental tissue after lambing. You don't have to harass pregnant women who these days are likely to eat it for nourishment.
Now if you are really game, there is raw liver juice. In fact, just placing the liver over your eyes and then eating it works well too. I think I prefer having liver juice in my rather than raw liver sitting on my face. The ancients worked out the benefit of liver which kinda makes us look stupid. There are many options including honey than having to resort to MB. Always put yourself in your cells shoes and think about what they would like. Work with them instead of against them.
Night Blindness and Ancient Remedy
How many of you eat regular liver and oysters?
MB is use to treat bacterial and fungal infections in fish.
Ophthalmology of Exotic Pets
Read on adverse reactions and contra-indications at the following link.
Clinical Ocular Pharmacology
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707430/
The following paper provides clues on how well MB penetrates corneal layers. Also demonstrates an excellent technique in drug delivery into the corneal layers. I am not advocating you explore this with MB.
http://www.sciencedirect.com/science/article/pii/S0928098716301749
The following is a step by step on how to make your own autologous serum. Read thoroughly and be extremely scrupoulos in preventing microbial contamination. The setup cost should not be too expensive when you consider what you would pay to have a specialist do it. Remember, you need to be meticulous - not slap dash with infection control.
https://www.reviewofoptometry.com/article/how-and-why-to-make-autologous-serum