nicotinamide riboside

  1. haidut

    Chronic pain due to mitochondrial dysfunction, niacinamide can treat it

    As many of my readers know, there is an epidemic of chronic pain disorders in Western countries, which has subsequently led to over-prescription and (ab)use of opioid medication, which has then acted as a gateway drug and fueled a massive and deadly opioid epidemic in those countries. In order...
  2. haidut

    Niacinamide may treat Parkinson Disease (PD)

    A very interesting study, which used a relatively high dose of nicotinamide riboside (NR) to treat Parkinson Disease (PD). The dosage used was 3,000mg daily for 4 weeks and it resulted in improvement of motor and cognitive symptoms of PD, while producing no side effects. The study references...
  3. haidut

    Age-related steroid deficiency may be treatable with niacinamide

    The study is actually about eye health, and the effects androgens play in it. However, the findings are not limited to the eyes and are in fact applicable for any other tissue/organ experiencing a decline in steroidogenesis with advancing age, which is basically all of them. As such, I am...
  4. Ismail

    Endotoxin (LPS) drives CD38 expression and therefore seems to effect NAD levels

    How To Inhibit CD38 As We Age | LPS Drives CD38 Expression | Prof Covarrubias Interview Series Ep5
  5. haidut

    Niacinamide May Help Treat/reverse Heart Disease

    Yet another study showing the beneficial effects of improving mitochondrial function. This time, the study looked at heart health and found that NAD precursors like niacinamide and nicotinamide riboside (NR) can help prevent the decline in mitochondrial function and oxygen consumption driven by...
  6. haidut

    Giving Niacinamide To Pregnant Females Greatly Benefits The Offspring

    A few very interesting studies came out in 2018 showing that niacinamide may be very helpful for (pre)-eclampsia, as well as prevent miscarriages and birth defects. Keep in mind that according to mainstream medicine, eclampsia is untreatable and the approach is to have the baby delivered ASAP...
  7. haidut

    Niacinamide Can Treat Alcoholic Liver Disease

    As many forum users have probably heard on the news, alcohol abuse is now a leading cause of death in young people under 35. It is projected to soon surpass drug overdose as a cause of death in this demographic. Millennials are dying of alcohol-related liver disease at increasing rates The...
  8. haidut

    Niacinamide May Be A Viable Treatment For Parkinson Disease (PD)

    It looks like the pharma industry is experiencing a resurgence in the search for metabolic therapies with patented chemicals. There must have been at least 50 different studies in 2017 alone with the NAD precursor nicotinamide riboside (NR) for conditions ranging from cancer, to glaucoma, to...
  9. haidut

    Niacinamide Lowers BP, May Reverse CVD And Reduce Heart Attack Risk By 25%

    This is a human study, so the findings are that much more relevant even though they probably do not come as a surprise to users of this forum. The duration of the study was just 6 weeks and the dose was 500mg nicotinamide riboside (NR) twice a day (for a total of 1,000mg). There were no side...
  10. S

    Nicotinamide Riboside Experiences

    Not exactly "Ray Peat", but it would be nice to hear some subjective reports. Nicotinamide riboside is also known as Niagen.
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