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The study is observational and does not really include information on specific dosing, but it was written in a way that suggests any exposure to vitamin D over a year was linked to significantly lower risk of both getting dementia/AD and/or dying from it over the next 5 years. Considering the...
by Michele R. Berman, MD December 1, 2022
Australian actor Chris Hemsworth, best known for his role as Thor in the Marvel Universe, revealed he is at increased risk of developing Alzheimer's disease due to a genetic predisposition. Hemsworth learned this while filming a new National Geographic...
The bad news for PUFA (in this case linoleic acid) just keep piling on. At this point, there is hardly a chronic condition out there that has not been linked to elevated PUFA and/or their peroxidation products. The first study below makes the argument that PUFA peroxidation byproducts (created...
As Aβ plaques accumulate in the brain, microglia are increasingly called upon to clean up the mess. This relentless phagocytic feasting requires enormous amounts of energy in the form of adenosine triphosphate, but by boosting glycolysis, the microglia fail to provide enough ATP, according to a...
Abstract
Introduction: Molecular hydrogen (H2) has emerged as a therapeutic medical gas that exerts multiple functions. H2 inhalation has been approved as safe, and some clinical studies showed that it effectively improved conditions of patients with a variety of disorders such as stroke, heart...
I have made posts on this topic in the past, but it seems this most recent study directly states that endotoxin/LPS is a major cause of AD. All other studies have been either animal models or did not directly implicate LPS. The study below claims to be the first that integrates all available...
It rarely gets any more damning for a scientific field than what was just announced today. Namely, the study considered the most important/influential in maintaining scientific support for the central dogma of dementia research - the beta-amyloid hypothesis of Alzheimer Disease (AD) - was not...
https://archive.ph/xeegP
“The key theory of what causes Alzheimer’s disease may be based on ‘manipulated’ data which has misdirected dementia research for 16 years – potentially wasting billions of pounds – a major investigation suggests.” - Daily Telegraph
Over the last couple of months, a few studies came out arguing (again) that aspirin is not worth the risk and that people should stop taking it. It seems that Big Pharma has a schedule of pumping propaganda out every year or so against the main "threats" to its dominance - aspirin, vitamin D...
After decades of denial that AD is a metabolic condition, Big Pharma and Big Govt, are silently doing an 180-degree turn by secretly funding university clinical trials for metabolic interventions in that disease. The study below will evaluate the effects of benfotiamine - a lipophilic analog of...
A meta-review study I posted about years ago stated openly that 99% of all clinical trials for Alzheimer Disease (AD) have failed. In addition, another recent post of mine discussed that the very theory underpinning most Alzheimer research was actually FRAUDULENT...
A great new study, which is one of the very few to examine the safety and effectiveness of allopregnanolone in humans. The trial was conducted in patients with Alzheimer Disease (AD) and aimed to establish the safety of various doses of once-weekly allopregnanolone administration, as well as any...
The title is an actual quote from the article, so there is no editorializing on my part and it speaks volumes about how the authors feel about their findings. In addition, opposite effects were found for saturated fats, in this case coconut oil, which leads the authors to once again remind...
A neat study, which somehow managed to slip through my "radar" when it was first published the middle of last (2021) year. The study is pretty straighforward in its claim that longer exposure to endogenous estrogen was associated with exacerbated/higher biomarkers of Alzheimer disease (AD), as...
The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer’s disease
Abstract
Increased dietary intake of niacin has been correlated with reduced risk of Alzheimer’s disease (AD). Niacin serves as a high-affinity ligand for the receptor...
The utter corruption of "journalism" is once again on full display in MSM. The actual scientific study is very clear in its statements/conclusions that a decrease in the levels of serotonin transporter (5-HTT) led to accumulation of beta-amyloid and onset of depression. Lower levels of 5-HTT -...
...and improve cognition even in healthy people! The mechanism of action is the familiar effects of red/infrared light on stimulating mitochondrial function, and especially complex IV, while also decreasing chronic inflammation. The regimen was light exposure for 6min, twice a day, for 4 weeks...
Just a quick post in regards to a study that found the drug donepezil - commonly used to "treat" Alzheimer's Disease (AD) - may improve mitochondrial function in muscles. While the findings of the study in regards to donepezil are debatable and not particularly interesting, buried inside the...
A remarkable study, that for some reason is not being covered by mainstream media. Considering 99% of the clinical trials for AD since 2000 have completely failed, this study should be front-page news for most mainstream outlets. I suspect mainstream media, being literally owned by the same...