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alzheimer

  1. haidut

    Vitamin D may prevent dementia / Alzheimer's Disease (AD)

    The study is observational and does not really include information on specific dosing, but it was written in a way that suggests any exposure to vitamin D over a year was linked to significantly lower risk of both getting dementia/AD and/or dying from it over the next 5 years. Considering the...
  2. AlphaCog

    Chris Hemsworth's APOE4 Alzheimer's Gene — The Thor actor recently learned about his genetic predisposition.

    by Michele R. Berman, MD December 1, 2022 Australian actor Chris Hemsworth, best known for his role as Thor in the Marvel Universe, revealed he is at increased risk of developing Alzheimer's disease due to a genetic predisposition. Hemsworth learned this while filming a new National Geographic...
  3. haidut

    Diabetes, Alzheimer's, cancer are bioenergetic diseases; PUFA may be the cause

    The bad news for PUFA (in this case linoleic acid) just keep piling on. At this point, there is hardly a chronic condition out there that has not been linked to elevated PUFA and/or their peroxidation products. The first study below makes the argument that PUFA peroxidation byproducts (created...
  4. A

    Forced Into Fat-Burning Mode, Microglia Gobble Up Plaques, Protect Neurons

    As Aβ plaques accumulate in the brain, microglia are increasingly called upon to clean up the mess. This relentless phagocytic feasting requires enormous amounts of energy in the form of adenosine triphosphate, but by boosting glycolysis, the microglia fail to provide enough ATP, according to a...
  5. A

    Long-Term Inhalation of Hydrogen Gas for Patients with Advanced Alzheimer's Disease: A Case Report

    Abstract Introduction: Molecular hydrogen (H2) has emerged as a therapeutic medical gas that exerts multiple functions. H2 inhalation has been approved as safe, and some clinical studies showed that it effectively improved conditions of patients with a variety of disorders such as stroke, heart...
  6. haidut

    Endotoxin (LPS) causes Alzheimer Disease (AD)

    I have made posts on this topic in the past, but it seems this most recent study directly states that endotoxin/LPS is a major cause of AD. All other studies have been either animal models or did not directly implicate LPS. The study below claims to be the first that integrates all available...
  7. haidut

    BREAKING: Seminal study, core of the amyloid-Alzheimer theory, was FABRICATED!

    It rarely gets any more damning for a scientific field than what was just announced today. Namely, the study considered the most important/influential in maintaining scientific support for the central dogma of dementia research - the beta-amyloid hypothesis of Alzheimer Disease (AD) - was not...
  8. F

    Amyloid plaque theory of Alzheimers based on fraudulent data

    https://archive.ph/xeegP “The key theory of what causes Alzheimer’s disease may be based on ‘manipulated’ data which has misdirected dementia research for 16 years – potentially wasting billions of pounds – a major investigation suggests.” - Daily Telegraph
  9. haidut

    Low-dose aspirin may prevent most dementias (even Alzheimer's)

    Over the last couple of months, a few studies came out arguing (again) that aspirin is not worth the risk and that people should stop taking it. It seems that Big Pharma has a schedule of pumping propaganda out every year or so against the main "threats" to its dominance - aspirin, vitamin D...
  10. haidut

    Vitamin B1 as a potential treatment for Alzheimer's Disease (AD)

    After decades of denial that AD is a metabolic condition, Big Pharma and Big Govt, are silently doing an 180-degree turn by secretly funding university clinical trials for metabolic interventions in that disease. The study below will evaluate the effects of benfotiamine - a lipophilic analog of...
  11. haidut

    A real medical "conspiracy" is the reason for failure of Alzheimer treatments

    A meta-review study I posted about years ago stated openly that 99% of all clinical trials for Alzheimer Disease (AD) have failed. In addition, another recent post of mine discussed that the very theory underpinning most Alzheimer research was actually FRAUDULENT...
  12. haidut

    Allopregnanolone found safe, may slow brain atrophy from Alzheimer's

    A great new study, which is one of the very few to examine the safety and effectiveness of allopregnanolone in humans. The trial was conducted in patients with Alzheimer Disease (AD) and aimed to establish the safety of various doses of once-weekly allopregnanolone administration, as well as any...
  13. Sefton10

    Mitochondrial Calcium: Effects of Its Imbalance in Disease

    Mitochondrial Calcium: Effects of Its Imbalance in Disease https://www.mdpi.com/2076-3921/11/5/801/htm
  14. haidut

    PUFA cause obesity, diabetes, autism, Alzheimer's disease, anxiety, and depression

    The title is an actual quote from the article, so there is no editorializing on my part and it speaks volumes about how the authors feel about their findings. In addition, opposite effects were found for saturated fats, in this case coconut oil, which leads the authors to once again remind...
  15. haidut

    Alzheimer's Severity Tied to Longer Estrogen Exposure in Women

    A neat study, which somehow managed to slip through my "radar" when it was first published the middle of last (2021) year. The study is pretty straighforward in its claim that longer exposure to endogenous estrogen was associated with exacerbated/higher biomarkers of Alzheimer disease (AD), as...
  16. A

    Niacin receptor agonists may prevent the progression of Alzheimer’s disease

    The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer’s disease Abstract Increased dietary intake of niacin has been correlated with reduced risk of Alzheimer’s disease (AD). Niacin serves as a high-affinity ligand for the receptor...
  17. haidut

    High (extracellular) serotonin causes Alzheimer's and depression

    The utter corruption of "journalism" is once again on full display in MSM. The actual scientific study is very clear in its statements/conclusions that a decrease in the levels of serotonin transporter (5-HTT) led to accumulation of beta-amyloid and onset of depression. Lower levels of 5-HTT -...
  18. haidut

    Infrared/red light applied to the skull can treat Alzheimer's/dementia...

    ...and improve cognition even in healthy people! The mechanism of action is the familiar effects of red/infrared light on stimulating mitochondrial function, and especially complex IV, while also decreasing chronic inflammation. The regimen was light exposure for 6min, twice a day, for 4 weeks...
  19. haidut

    Alzheimer's patients have lower metabolic rate and higher fatty acid oxidation

    Just a quick post in regards to a study that found the drug donepezil - commonly used to "treat" Alzheimer's Disease (AD) - may improve mitochondrial function in muscles. While the findings of the study in regards to donepezil are debatable and not particularly interesting, buried inside the...
  20. haidut

    Human study - vitamin B1 safe & effective for preventing & treating Alzheimer Disease (AD)

    A remarkable study, that for some reason is not being covered by mainstream media. Considering 99% of the clinical trials for AD since 2000 have completely failed, this study should be front-page news for most mainstream outlets. I suspect mainstream media, being literally owned by the same...
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