alzheimer

  1. haidut

    STUDY: high serotonin linked to dementia; MEDIA: low serotonin linked to dementia

    Once again, a level of misreporting that I am much more included to ascribe to malice than incompetence simply because most of the popular press outlets covering a specific scientific study get the study authors to proof-read the press article before publishing. So, for patently false press...
  2. AlphaCog

    Dietary choline intake is necessary to prevent systems-wide organ pathology and reduce Alzheimer's disease hallmarks

    Abstract There is an urgent need to identify modifiable environmental risk factors that reduce the incidence of Alzheimer's disease (AD). The B-like vitamin choline plays key roles in body- and brain-related functions. Choline produced endogenously by the phosphatidylethanolamine...
  3. haidut

    PARADOX: Cortisol promotes inflammation, drives Alzheimer's Disease (AD)

    It looks like serotonin (5-HT), commonly known as the "happy hormone" has a serious competitor for the title of the most grossly mischaracterized substance in medicine. That serious competitor is cortisol, in both its synthetic and bioidentical forms, commonly known as the "master of...
  4. A

    Vinegar may protect against Alzheimer's disease

    Acetic acid is a short-chain fatty acids. It makes up approximately 4 to 20 percent of vinegar. Urinary excretion of acetone (a ketone body) is increased in dogs and rats after acetic acid feeding. Acetone is a spontaneous breakdown product of the ketone bodies acetoacetate and...
  5. Mauritio

    Coffee/Caffeine might help alzheimers

    "Espresso coffee is among the most consumed beverages in the world. Recent studies report a protective activity of the coffee beverage against neurodegenerative disorders such as Alzheimer′s disease. Alzheimer′s disease belongs to a group of disorders, called tauopathies, which are characterized...
  6. haidut

    Human trial - niacinamide may treat Alzheimer Disease (AD)

    One of my first posts on the topic of bioenergetics - more than a decade ago - was in regards to a promising animal study with the human-equivalent dose (HED) of 30mg/kg niacinamide (NAM) daily showing robust effects on that animal species' model of AD. The authors of the animal study followed...
  7. haidut

    High serotonin linked to poor aging trajectory (brain atrophy and depression)

    This is one of the studies that Big Pharma will probably spend a lot of money on trying to get retracted. It directly demonstrates that elevated serotonin (5-HT) in the brain drives brain atrophy and depression. Both the rates and severity of these conditions increase with aging and the study...
  8. haidut

    Serotonin (5-HT) may drive both schizophrenia and Alzheimer Disease (AD)

    Unbeknownst to most people, psychiatry has started to make a quiet "paradigm shift" in regards to psychotic conditions such as schizophrenia. Namely, after claiming for decades that psychotic states are caused by excessive dopamine levels/activity, psychiatry has now quietly change the official...
  9. haidut

    Vitamin D may prevent dementia / Alzheimer's Disease (AD)

    The study is observational and does not really include information on specific dosing, but it was written in a way that suggests any exposure to vitamin D over a year was linked to significantly lower risk of both getting dementia/AD and/or dying from it over the next 5 years. Considering the...
  10. AlphaCog

    Chris Hemsworth's APOE4 Alzheimer's Gene — The Thor actor recently learned about his genetic predisposition.

    by Michele R. Berman, MD December 1, 2022 Australian actor Chris Hemsworth, best known for his role as Thor in the Marvel Universe, revealed he is at increased risk of developing Alzheimer's disease due to a genetic predisposition. Hemsworth learned this while filming a new National Geographic...
  11. haidut

    Diabetes, Alzheimer's, cancer are bioenergetic diseases; PUFA may be the cause

    The bad news for PUFA (in this case linoleic acid) just keep piling on. At this point, there is hardly a chronic condition out there that has not been linked to elevated PUFA and/or their peroxidation products. The first study below makes the argument that PUFA peroxidation byproducts (created...
  12. A

    Forced Into Fat-Burning Mode, Microglia Gobble Up Plaques, Protect Neurons

    As Aβ plaques accumulate in the brain, microglia are increasingly called upon to clean up the mess. This relentless phagocytic feasting requires enormous amounts of energy in the form of adenosine triphosphate, but by boosting glycolysis, the microglia fail to provide enough ATP, according to a...
  13. A

    Long-Term Inhalation of Hydrogen Gas for Patients with Advanced Alzheimer's Disease: A Case Report

    Abstract Introduction: Molecular hydrogen (H2) has emerged as a therapeutic medical gas that exerts multiple functions. H2 inhalation has been approved as safe, and some clinical studies showed that it effectively improved conditions of patients with a variety of disorders such as stroke, heart...
  14. haidut

    Endotoxin (LPS) causes Alzheimer Disease (AD)

    I have made posts on this topic in the past, but it seems this most recent study directly states that endotoxin/LPS is a major cause of AD. All other studies have been either animal models or did not directly implicate LPS. The study below claims to be the first that integrates all available...
  15. haidut

    BREAKING: Seminal study, core of the amyloid-Alzheimer theory, was FABRICATED!

    It rarely gets any more damning for a scientific field than what was just announced today. Namely, the study considered the most important/influential in maintaining scientific support for the central dogma of dementia research - the beta-amyloid hypothesis of Alzheimer Disease (AD) - was not...
  16. F

    Amyloid plaque theory of Alzheimers based on fraudulent data

    https://archive.ph/xeegP “The key theory of what causes Alzheimer’s disease may be based on ‘manipulated’ data which has misdirected dementia research for 16 years – potentially wasting billions of pounds – a major investigation suggests.” - Daily Telegraph
  17. haidut

    Low-dose aspirin may prevent most dementias (even Alzheimer's)

    Over the last couple of months, a few studies came out arguing (again) that aspirin is not worth the risk and that people should stop taking it. It seems that Big Pharma has a schedule of pumping propaganda out every year or so against the main "threats" to its dominance - aspirin, vitamin D...
  18. haidut

    Vitamin B1 as a potential treatment for Alzheimer's Disease (AD)

    After decades of denial that AD is a metabolic condition, Big Pharma and Big Govt, are silently doing an 180-degree turn by secretly funding university clinical trials for metabolic interventions in that disease. The study below will evaluate the effects of benfotiamine - a lipophilic analog of...
  19. haidut

    A real medical "conspiracy" is the reason for failure of Alzheimer treatments

    A meta-review study I posted about years ago stated openly that 99% of all clinical trials for Alzheimer Disease (AD) have failed. In addition, another recent post of mine discussed that the very theory underpinning most Alzheimer research was actually FRAUDULENT...
  20. haidut

    Allopregnanolone found safe, may slow brain atrophy from Alzheimer's

    A great new study, which is one of the very few to examine the safety and effectiveness of allopregnanolone in humans. The trial was conducted in patients with Alzheimer Disease (AD) and aimed to establish the safety of various doses of once-weekly allopregnanolone administration, as well as any...
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