5-ht

Yet another blow to the status of the so-called "happiness hormone". While histamine, acetylcholine, and estrogen have long been known as key drivers of asthma the link between the mast cells and the nervous system's production of the vasoconstrictor acetylcholine has remained unknown. The study...

So much for the "happiness hormone", which medicine keeps telling us should be kept as high as possible. This idiotic hypothesis gave birth to an entire drug industry, which continues to poison people to this day with its SSRI drugs, despite solid evidence that they are no better than placebo...

This study says: Beyond the gut, germ free mice also display an increased turnover rate of dopamine and norepinephrine (as well as serotonin) in the brain (Diaz Heijtz et al., 2011), which could generally reduce pools in systemic circulation independent of microbial production (although factors...

This study alone explains so much of the pathological behavior seen in humans living in developed countries. Namely, the vast majority of them are willing to break their backs working and "delaying gratification" in the hopes that one day they will "make it" and all of their efforts will be...

One by one, medical myths (slowly) go the way of the Dodo. Two of the most pervasive such myths are that psychotic conditions like schizophrenia are caused by excess dopamine, and Parkinson Disease (PD) is caused by a deficiency of dopamine. Unbeknownst even to most doctors, studies exist...

I did not expect to see this statement in a mainstream science news outlet, but here it is below. I am starting to see a change in attitude towards serotonin but mainstream medicine is careful about its game. Somehow, the message about serotonin has now split into two separate, nonsensical ones...

The article below is one of at least 20 I have seen in just 2020 alone that are starting to draw attention to the metabolic/inflammatory origins of yet another neurological disease of "mysterious" origin - namely, Parkinson Disease (PD). What makes this article both interesting and infuriating...

The bad news for serotonin just keeps on coming. Just minutes ago I posted about serotonin turning people into violent criminals, and being the actual cause of depression instead of its cure (as FDA and Big Pharma would have you believe). Now, the study below adds another pathology that is...

The bad news for serotonin (5-HT) just keeps accumulating. Aside from its well-known (outside of medical office, of course) effects on causing pretty much any mental illness defined in DSM V, as well as fibrosis in any organ/tissue unfortunate enough to be exposed to 5-HT now we can add...

Yet another medical myth gets busted today. A common dogma in psychiatry is that one of the core symptoms of patients with major depressive disorder (MDD) is lack of empathy. In other words, while such patients are perfectly in tune with their own suffering and negative emotions, they are...

The two conditions mentioned in the title of the post are quite pervasive among Western societies and their cause is, of course, officially labelled as unknown. While medicine claims that no treatment exists for tinnitus the only approved curative treatment for hemorrhoids is surgery and like...

As my readers know, I have posted quite a few threads in the past on the topic of PTSD. It is a condition that affects up to 30% of current/former military members, and is considered a condition of unknown cause and without treatment. Current treatment options consist of mostly symptom...

I neat new study that draws a direct parallel between PUFA-driven inflammation, serotonin and depression. As the study demonstrated, high levels of the PUFA arachidonic acid (AA) are highly correlated with lower density (expression) of the serotonin transported (SERT, 5-HTT), and the...

Over the last year I posted a number of studies demonstrating strong link between serotonin and chronic conditions such as obesity, insulin resistance, and even diabetes. Augmented capacity for peripheral serotonin release in human obesity...

Almost four years ago I posted a study implicating elevated serotonin in autism and that study also showed that administering serotonin receptor antagonists was effective in reversing the pathology. Serotonin Causes Autism; Blocking It May Treat Autism And now, another study not only points the...

Peat wrote in a few articles that serotonin is extremely detrimental for bone growth and that anti-serotonin drugs are anabolic for the bone. Serotonin is the most potent inducer of cortisol synthesis, which is probably the main mechanism behind its bone destructive effects. However, serotonin...

Yet another nail in the coffin of the "happiness hormone", which may end up being one of the biggest scientific frauds of the 20th century, rivaling the one about estrogen being the "female" hormone. It has been known for a long time that both lithium and methylene blue, both of which are...

This is one of the unique studies that breaks away from the mainstream dogma that serotonin is the "happy hormone" and increasing it with drugs like SSRI can lead to nothing but goodness. The study not only directly states that past/current SSRI use is a risk for developing diabetes but show how...

I am hoping that as a result of this study, mainstream medicine will finally start to take the pathogenic role of peripheral serotonin more seriously. More importantly, this study points to a rather simple and safe way of treating two of deadliest acute reactions (sepsis and allergic shock)...

The role of serotonin in fibrosis is well-known despite the public lies thrown around by Big Pharma. I opsted about the behind-the-scenes acquisition of the serotonin antagonist terguride, which Pfizer is now hoping to be able to treat ANY fibrotic condition (as shown by a recently filed FDA...