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You think ARB is safer than ACEI, CCB and thiazides diuretics?Losartan and other ARBs
ARB and thiazide diuretics seem the safest. The stuff with ARBs and COVID is interestingDr Peat has spoken favorably about the ARBs because they have anti inflammatory effects.
Dr. Peat has said ACE inhibitors, ARBs and Ca channel blockers which lower blood pressure "stabilize the living state of the cell" probably by working on the inflammatory system. "The way they are explained isn't very illuminating, but they are actually protecting cells against high estrogen, high lactic acid, deficient sugar and CO2." (Butter Living Podcast - Fertility Pregnancy & Development at 1:00:20)Don’t suggest supplements please, I need something that works. I’ve already tried supplements and they only help a tiny bit.
I have to optimise my thyroid too.Optimizing my husband's natural desiccated thyroid prescription medication via a good endocrinologist improved his hypertension so well that he was able to get off his prescription Lisinopril completely. Lucky for me because he was a raging maniac on that stuff. He no longer has high blood pressure.
You think thiazide diuretics are harmful?I've just looked into this, looking at long-term mortality with HBP meds. It's shocking how many meds do reduce blood pressure - yay - but also cause people to DIE sooner. Not yay.Hydrochlorothiazide should have been pulled years ago - yet it's still a go-to medicine. The upside to their "pamphlet" approach is that doctors seem less committed to one over the other, and are open to requests for alternatives.
More people discontinue calcium channel blockers due to side effects than ACEs and ARBs.Dr. Peat has said ACE inhibitors, ARBs and Ca channel blockers which lower blood pressure "stabilize the living state of the cell" probably by working on the inflammatory system. "The way they are explained isn't very illuminating, but they are actually protecting cells against high estrogen, high lactic acid, deficient sugar and CO2." (Butter Living Podcast - Fertility Pregnancy & Development at 1:00:20)
You think thiazide diuretics are harmful?
Some good points, but I don't think agree that the "body thinks it's the best way". Bodies have a LOT of moving, complex parts, that work amazingly well at least to survive and procreate. But for the vast majority of our species' existence we were done by 35 so. What happens after that - why our bodies break down and how - wasn't part of our evolutionary past. It just didn't matter - if a 65 year old like me keeled over from cardiovascular disease or some other growing imbalance.Lowering BP isn't easy. Too many variables. It takes a lifetime of research just to figure out mine, and I'm still halfway through it.
Ray Peat endorses many bp lowering drugs, and I think it is because of the futility of lowering it naturally. And the only way I know he has recommended lowering bp is by the use of vitamin k2, which works if you fit that that profile, whatever that profile is. It hasn't worked for me.
Ray even recommends the use of ARBS as an ACE II inhibitor for COVID. And it's especially said to be useful for people who have hypertension. But I have very high hypertension, and I don't take any prescription medication for it. And I'm not even affected by COVID. I just go out and about, but I wear masks only because everyone else is and it's the law where I'm at.
However, I don't live in the US and I'm not scared of not having healthcare insurance. If I were in the US, I may be forced to take bp lowering drugs because if I don't show my healthcare insurance provider that I have low blood pressure, I won't get a good plan or my plan may become more expensive. In the Philippines, I may not even get a plan. I don't think I'm any more healthier if I show low blood pressure, simply because I'm taking drugs to lower it.
The drugs just hide the symptoms. It doesn't fix anything. It doesn't keep my blood vessels from bursting from the high bp. It doesn't destoy my kidneys either, contrary to what medical experts say. I even believe taking high bp medication accelerates the destruction of kidneys. in 20 days year of steadily increasing bp, my serum creatinine values stay the same. Yet the funny thing is my glomerular filtration rate (GFR) keeps decreasing and I should be alarmed because clank clank I am in chronic kidney disease territory.
But why is my GFR that low? Because the medical complex calculates my gfr based on my serum creatinine and my age. Guess what? I'm not getting any younger, and so my gfr keeps getting lower - and it's solely because of the stupid formula being used to calculate my gfr.
I think as much as Ray Peat likes living natural and eating natural, his endorsement of high bp medications is a step backward. I think it's maybe due to the fact that it is very hard to fix high bp, and he could easily be sued for suggesting ways to lower bp without the use of prescription drugs.
I view bp the same way I view heart rate. It's that way because the body thinks it's best that way. Why isn't the heart rate as high as you'd like it? It's because, first of all, high heart rate isn't always good, what if your heart isn't pumping efficiently and that is why the heart rate is that high? But let's say you aren't aware that is the case, and your heart rate is low, should you go see a doctor so he will prescribe you a drug that will increase your heart rate? If the answer is no, then why are you taking a bp drug that's making you lower blood pressure?
Why aren't you working on finding the cause and fixing the cause? What if you have a bad case of oral infection that you don't know about? Would taking bp lowering drugs fix that infection?
I don't know where you get your evidence. Especially on life span. As for your thinking that medicine expends life span, what kind of life are you talking about? The city life you live in lacking good nutrition? I would agree if that is the life you are referring to.Some good points, but I don't think agree that the "body thinks it's the best way". Bodies have a LOT of moving, complex parts, that work amazingly well at least to survive and procreate. But for the vast majority of our species' existence we were done by 35 so. What happens after that - why our bodies break down and how - wasn't part of our evolutionary past. It just didn't matter - if a 65 year old like me keeled over from cardiovascular disease or some other growing imbalance.
After 50 or so we are pretty much on borrowed time, and unnatural medicine can keep us running well enough when "naturally" we'd be long gone.
I don't respond to K2 either. Nor to just about every other "Peaty" substance I've tried. Except for a few notable exceptions, I'm like teflon to that stuff. The evidence is that the right medicines do more than just hide symptoms - they actually extend life. I'm all for that.
OK apologies for having an opinion. I'll leave you to your "natural" fetish.I don't know where you get your evidence. Especially on life span. As for your thinking that medicine expends life span, what kind of life are you talking about? The city life you live in lacking good nutrition? I would agree if that is the life you are referring to.