Diokine
Member
- Joined
- Mar 2, 2016
- Messages
- 624
I have had great success with Holy Basil tea in reducing a number of symptoms related to high histamine, serotonin, as well as reducing anxiety and nervousness associated with high adrenaline. I've always known that it was a very powerful compound, and some research I've come across recently seems to confirm this.
Biological activities of Ocimum sanctum L. fixed oil--an overview.
Tulsi - Ocimum sanctum: A herb for all reasons
Tulsi's unique combination of antibacterial antioxidant, anti-inflammatory and analgesic activities also makes it useful in wound healing.[109,110] This is supported by experimental evidence that has shown that tulsi can increase wound-breaking strength and accelerate wound healing in laboratory animals.[110,111] Tulsi has also been shown to have anti-ulcer and ulcer-healing activity that has been observed in many different animal models including aspirin-, indomethacin-, alcohol-, histamine-, reserpine-, serotonin-, acetic acid-, meloxicam-, cold restraint-, pyloric ligation- and stress-induced ulceration models.[25,112,113,114] This anti-ulcer activity is attributed to multiple actions including the reduction of offensive factors such as acid-pepsin secretion and lipid peroxidation and the enhancement of gastric defensive factors such as mucin secretion, cellular mucus and longevity of mucosal cells.
Evaluation of the gastric antiulcer activity of fixed oil of Ocimum sanctum (Holy Basil).
The fixed oil of Ocimum sanctum L. (Labiatae) was found to possess significant antiulcer activity against aspirin-, indomethacin-, alcohol-, histamine-, reserpine-, serotonin- and stress-induced ulceration in experimental animal models. Significant inhibition was also observed in gastric secretion and aspirin-induced gastric ulceration in pylorus ligated rats. The lipoxygenase inhibitory, histamine antagonistic and antisecretory effects of the oil could probably have contributed towards antiulcer activity. O. sanctum fixed oil may be considered to be a drug of natural origin which possesses both anti-inflammatory and antiulcer activity.
Here is an article on another herb I use occasionally, Gotu Kola.
Evaluation of Analgesic and Anti-Inflammatory Activity of Chloroform and Methanol Extracts of Centella asiatica Linn
Methanol extract had significant anti-inflammatory effect against carrageenan-induced paw edema model, whereas chloroform extract had not such effect on rats. Carrageenan induced inflammation is a well-established method to detect orally active anti-inflammatory agents which shows biphasic response. The first phase is mediated through the release of histamine, serotonin, and kinins, whereas the second phase is through the release of prostaglandins [23]. Methanol extract at 200 mg/kg dose showed maximum inhibition at 2 h (Table 6); this finding signified that anti-inflammatory action might be due to inhibiting the release of histamine or kinins.
Biological activities of Ocimum sanctum L. fixed oil--an overview.
Tulsi - Ocimum sanctum: A herb for all reasons
Tulsi's unique combination of antibacterial antioxidant, anti-inflammatory and analgesic activities also makes it useful in wound healing.[109,110] This is supported by experimental evidence that has shown that tulsi can increase wound-breaking strength and accelerate wound healing in laboratory animals.[110,111] Tulsi has also been shown to have anti-ulcer and ulcer-healing activity that has been observed in many different animal models including aspirin-, indomethacin-, alcohol-, histamine-, reserpine-, serotonin-, acetic acid-, meloxicam-, cold restraint-, pyloric ligation- and stress-induced ulceration models.[25,112,113,114] This anti-ulcer activity is attributed to multiple actions including the reduction of offensive factors such as acid-pepsin secretion and lipid peroxidation and the enhancement of gastric defensive factors such as mucin secretion, cellular mucus and longevity of mucosal cells.
Evaluation of the gastric antiulcer activity of fixed oil of Ocimum sanctum (Holy Basil).
The fixed oil of Ocimum sanctum L. (Labiatae) was found to possess significant antiulcer activity against aspirin-, indomethacin-, alcohol-, histamine-, reserpine-, serotonin- and stress-induced ulceration in experimental animal models. Significant inhibition was also observed in gastric secretion and aspirin-induced gastric ulceration in pylorus ligated rats. The lipoxygenase inhibitory, histamine antagonistic and antisecretory effects of the oil could probably have contributed towards antiulcer activity. O. sanctum fixed oil may be considered to be a drug of natural origin which possesses both anti-inflammatory and antiulcer activity.
Here is an article on another herb I use occasionally, Gotu Kola.
Evaluation of Analgesic and Anti-Inflammatory Activity of Chloroform and Methanol Extracts of Centella asiatica Linn
Methanol extract had significant anti-inflammatory effect against carrageenan-induced paw edema model, whereas chloroform extract had not such effect on rats. Carrageenan induced inflammation is a well-established method to detect orally active anti-inflammatory agents which shows biphasic response. The first phase is mediated through the release of histamine, serotonin, and kinins, whereas the second phase is through the release of prostaglandins [23]. Methanol extract at 200 mg/kg dose showed maximum inhibition at 2 h (Table 6); this finding signified that anti-inflammatory action might be due to inhibiting the release of histamine or kinins.