TiltMaster
Member
- Joined
- Jul 19, 2019
- Messages
- 11
All this chat about blocking DHT makes me sad. Blocking a hormone. To those considering it I'd say please don't. If not for yourself then how about for some random guy on Ray Peat Forum...like me. Pretty please? No actually please do it for yourself.
The DHT lowering aspect of fin is just one aspect of a drug that could have multiple actions. For example the candida fighting quality @mrchibbs posted earlier in the thread. Yeast produce several toxic substances such as oxylipins which actively slow metabolism. They can also decrease calcium absorbtion. Interestingly enough progesterone seems to possess this same yeast fighting quality.
A question I continually ask my medical profession friends is "Do you think the human body is stupid? Or do you think it reacts to a given problem in a biochemically intelligent way?" I'm still waiting on a satisfactory answer. I don't think it's coming.
If a hormone is elevated, it's because your body requires it to be elevated, in response to a problem, at the particular time it is elevated.
The reason fin causes problems for so many guys is the above. You cannot simply jump to the end stage of a problem and circumvent dealing with the stages that led to the development of that problem in the first place.
If you believe achieving optimal health is multifactorial, why would the creation of a health problem be any different? The one drug one disease mantra will never prove fruitful as a true and complete solution to any health problem, because it can't. Multiple disease pathways will never be resolved through the use of a single drug.
My opinion: Why would hair loss be any different?
The general consensus already is that an approach of multiple angles is the way to go regarding hair loss, but the science is simply not there yet. There are already quite a bunch of theories that all tackle a different aspect (prostaglandin theory, sonic hedgehog pathway, activation of Wnt signalling, etc) but we're so incredibly in the dark regarding almost everything (compound to use, dosage, frequency, etc). Some pathways we can tackle using existing compounds, but most are expensive (they're research chemicals) and for some pathways there are just no viable compounds yet.
Also, once we really get into the pathways that promote hair growth we are probably going to worry about cancer as a possible side effect as well.
But imo, most people trying to tackle aggressive hair loss aren't just inhibiting DHT. Even if you just use minoxidil and finasteride, you are already approaching hair loss from multiple angles.
Btw are you saying that male pattern baldness is a disease? Because I have never seen it like that.