5-AR Inhibitor Drugs Like Finasteride Cause Persistent ED And Lower Testosterone

[REOSIRENS]

Would progesterone and

androsterone be a good combo ?

To avoid the anti-androgenic effect of progesterone ?

If you took propecia it is better start with dhea pregnenolone... Progesterone in certain doses still inhibits 5ar

 

[johnwester130]

If you took propecia it is better start with dhea pregnenolone... Progesterone in certain doses still inhibits 5ar

yes

but in a completely different way than finasteride does

 

[REOSIRENS]

Yes... Progesterone see

yes

but in a completely different way than finasteride does

Yes Progesterone seems to be selective 5ar inhibitor...For me Progesterone is a must have but for people already with low testosterone would use with caution and try to go more to pregnenolone and dhea combo...and glycine beta alanine combo to restore frontal cortex activity...

Good luck man... If your regime is working say something... Have people here dealing with pfs that are doing better now with the combos I said but more positive feedback brings more knowledge for my studies...

 

[TubZy]

If you took propecia it is better start with dhea pregnenolone... Progesterone in certain doses still inhibits 5ar

That is why you take DHEA to eliminate that issue....

 

[mayweatherking]

Yes... Progesterone see

Yes Progesterone seems to be selective 5ar inhibitor...For me Progesterone is a must have but for people already with low testosterone would use with caution and try to go more to pregnenolone and dhea combo...and glycine beta alanine combo to restore frontal cortex activity...

Good luck man... If your regime is working say something... Have people here dealing with pfs that are doing better now with the combos I said but more positive feedback brings more knowledge for my studies...

why would people use it with caution if they have low T? it is anti cortisol and anti estrogen, both of which would inhibit testosterone.

 

[REOSIRENS]

why would people use it with caution if they have low T? it is anti cortisol and anti estrogen, both of which would inhibit testosterone.

Progesterone lowers estrogen and testosterone as well on certain doses...Pfs people have already tons of imbalances and lack raw material to testosterone production... Most potent cortisol inhibitors are dht/dhea and pregnenolone brings balance to body...I like Progesterone guys but pfs people don't react well to slightly more 5ar inhibition ... Progesterone uses quite a lot of your glycogen stores... pfs people can't store or lack a good deal of glucose... What I am saying give your system a kick of 5ar enhancement(dhea...Glycine... retinol...Magnesium...Thiamine...Beta alanine...Theanine.... glucose.... Pregnenolone) in the early stages and then bring back Progesterone to restore normality... Pfs people seem all have symptoms of frontal cortex dysfunction...

 

[mayweatherking]

Progesterone lowers estrogen and testosterone as well on certain doses...Pfs people have already tons of imbalances and lack raw material to testosterone production... Most potent cortisol inhibitors are dht/dhea and pregnenolone brings balance to body...I like Progesterone guys but pfs people don't react well to slightly more 5ar inhibition ... Progesterone uses quite a lot of your glycogen stores... pfs people can't store or lack a good deal of glucose... What I am saying give your system a kick of 5ar enhancement(dhea...Glycine... retinol...Magnesium...Thiamine...Beta alanine...Theanine.... glucose.... Pregnenolone) in the early stages and then bring back Progesterone to restore normality... Pfs people seem all have symptoms of frontal cortex dysfunction...

what is the mechanism exactly that causes it to lower testosterone? if it is a 5ar inhibitor, then if anything it would increase testosterone?

 

[REOSIRENS]

I know a pfs guy who craves for sweets almost all day...Sugar helps him function

 

[REOSIRENS]

what is the mechanism exactly that causes it to lower testosterone? if it is a 5ar inhibitor, then if anything it would increase testosterone?

Progesterone lowers(uses) cholesterol but if you don't have cholesterol you have high cortisol... At very low doses Progesterone is fine...I am not anti Progesterone I like it..
But pfs guys respond better with dhea/Pregnenolone...Makes them more social and confident and restores some of their normal features... Progesterone helps them but in very short run and sometimes brings back the bad crashes ... Almost all natural 5ar inhibitors lower cholesterol and cause depression to guys with low testosterone... Riboflavin taurine ribose tumeric calendula green tea superoxide dismutase manganese lauric acid they all cause depression and what they have in common 5ar inhibition...

 

[mayweatherking]

Progesterone lowers(uses) cholesterol but if you don't have cholesterol you have high cortisol... At very low doses Progesterone is fine...I am not anti Progesterone I like it..
But pfs guys respond better with dhea/Pregnenolone...Makes them more social and confident and restores some of their normal features... Progesterone helps them but in very short run and sometimes brings back the bad crashes ... Almost all natural 5ar inhibitors lower cholesterol and cause depression to guys with low testosterone... Riboflavin taurine ribose tumeric calendula green tea superoxide dismutase manganese lauric acid they all cause depression and what they have in common 5ar inhibition...

i figured it decreases cholesterol because it is allowing the body to use it, it is simiar to thyroid. why would it cause a crash? the problem in PFS is there is too much stress, many peope report very high cortisol levels across the board, the way i see it, it is either sugar or preg/prog combo to hit it or thyroid, but stress is really out of control.

 

[TubZy]

Progesterone lowers estrogen and testosterone as well on certain doses...Pfs people have already tons of imbalances and lack raw material to testosterone production... Most potent cortisol inhibitors are dht/dhea and pregnenolone brings balance to body...I like Progesterone guys but pfs people don't react well to slightly more 5ar inhibition ... Progesterone uses quite a lot of your glycogen stores... pfs people can't store or lack a good deal of glucose... What I am saying give your system a kick of 5ar enhancement(dhea...Glycine... retinol...Magnesium...Thiamine...Beta alanine...Theanine.... glucose.... Pregnenolone) in the early stages and then bring back Progesterone to restore normality... Pfs people seem all have symptoms of frontal cortex dysfunction...

I talked to at least ten people with PFS who have confirmed severely low progesterone levels and supplementing progesterone (even 5a-DHP) has helped them. I just talked to a guy yesterday on the phone for about an hour specifically about progesterone. There is a giant thread on solve PFS showing progesterone being the most effective. To @mayweatherking point, it makes sense why prog could be low during PFS because fin mimics prog in the body so when you get off it your endogenous levels are low with high cortisol, high estrogen, low thyroid, high prolactin etc. and nothing is opposing it anymore (like prog would) and you are stuck in a hypothyroid type state with downregulated 5AR enzymes.

PFS ppl can't store glycogen because of hypothyroidism which was induced from high cortisol, prolactin, serotonin, low allopreg, low GABA levels (causing continuous stress to burn through glycogen levels super quick) etc. Progesterone promotes hyperthyroidism which would then help improve glycogen stores and improve metabolic efficiency. No, PFS ppl cant take DHEA alone without feeling like a zombie because of the hypothyroid state. The cortisol antagonism is too strong when someone's thyroid isn't working properly to manage it. This was noted by many members personally on this forum.

Preg can help, it helped me personally. But the main reason it was helping me as it was dumping to progesterone as lower doses (under 50mg) didn't do much for me at all.

Cortisol inhibitors are not going to solve it alone, many many people have tried this before. If in a hypothyroid state, inhibiting cortisol too much can make things worse because your thyroid and enzymes isn't working properly to balance. Peat talks about this all the time along with Haidut. You can actually make things worse b/c you are stressing your metabolism more and nothing is there to support it, which is what exactly a "crash" is. I know this from first hand experience, since by taking supplements like DHEA for example, I can now handle if I take thyroid surrogates at the same time (caffeine + aspirin).

Progesterone is also anti cortisol too BTW : The Anti-cortisol Mechanism Of Progesterone

Again, you can offset any of the anti androgenic sides from prog by using DHEA. Peat has even said the same thing before in his writing specifically for men and it has worked for me personally.

High dose vitamin B-1 could be another alternative as a thyroid surrogate/T3 too.

 

[mayweatherking]

Progesterone lowers estrogen and testosterone as well on certain doses...Pfs people have already tons of imbalances and lack raw material to testosterone production... Most potent cortisol inhibitors are dht/dhea and pregnenolone brings balance to body...I like Progesterone guys but pfs people don't react well to slightly more 5ar inhibition ... Progesterone uses quite a lot of your glycogen stores... pfs people can't store or lack a good deal of glucose... What I am saying give your system a kick of 5ar enhancement(dhea...Glycine... retinol...Magnesium...Thiamine...Beta alanine...Theanine.... glucose.... Pregnenolone) in the early stages and then bring back Progesterone to restore normality... Pfs people seem all have symptoms of frontal cortex dysfunction...

you know, i actually understand what you are saying now. yes, it does make sense. did you have this experience? i do agree with you, progesterone will increase estrogen if the other DHEA side hormones are not present. can you talk more on this how you figured this out? you are right, they are low on cholosterol and thus low on T.

 

[REOSIRENS]

A healthy body dances in a perfect hormonal balance... The three anti aging hormones Progesterone/dhea/pregnenolone work closely together trying to use each other to a healthy end goal ... Progesterone high with other two low doesn't work and vice versa... Point is finding the best balance possible ...

PS hormones play a important role in keeping and activating or excreting vitamins minerals and other nutrients

 

[REOSIRENS]

I talked to at least ten people with PFS who have confirmed severely low progesterone levels and supplementing progesterone (even 5a-DHP) has helped them. I just talked to a guy yesterday on the phone for about an hour specifically about progesterone. There is a giant thread on solve PFS showing progesterone being the most effective. To @mayweatherking point, it makes sense why prog could be low during PFS because fin mimics prog in the body so when you get off it your endogenous levels are low with high cortisol, high estrogen, low thyroid, high prolactin etc. and nothing is opposing it anymore (like prog would) and you are stuck in a hypothyroid type state with downregulated 5AR enzymes.

PFS ppl can't store glycogen because of hypothyroidism which was induced from high cortisol, prolactin, serotonin, low allopreg, low GABA levels (causing continuous stress to burn through glycogen levels super quick) etc. Progesterone promotes hyperthyroidism which would then help improve glycogen stores and improve metabolic efficiency. No, PFS ppl cant take DHEA alone without feeling like a zombie because of the hypothyroid state. The cortisol antagonism is too strong when someone's thyroid isn't working properly to manage it. This was noted by many members personally on this forum.

Preg can help, it helped me personally. But the main reason it was helping me as it was dumping to progesterone as lower doses (under 50mg) didn't do much for me at all.

Cortisol inhibitors are not going to solve it alone, many many people have tried this before. If in a hypothyroid state, inhibiting cortisol too much can make things worse because your thyroid and enzymes isn't working properly to balance. Peat talks about this all the time along with Haidut. You can actually make things worse b/c you are stressing your metabolism more and nothing is there to support it, which is what exactly a "crash" is. I know this from first hand experience, since by taking supplements like DHEA for example, I can now handle if I take thyroid surrogates at the same time (caffeine + aspirin).

Progesterone is also anti cortisol too BTW : The Anti-cortisol Mechanism Of Progesterone

Again, you can offset any of the anti androgenic sides from prog by using DHEA. Peat has even said the same thing before in his writing specifically for men and it has worked for me personally.

High dose vitamin B-1 could be another alternative as a thyroid surrogate/T3 too.

Yes Progesterone seems to work good with nutrients and hormones that increase blood sugar (dhea/thiamine)

 

[REOSIRENS]

you know, i actually understand what you are saying now. yes, it does make sense. did you have this experience? i do agree with you, progesterone will increase estrogen if the other DHEA side hormones are not present. can you talk more on this how you figured this out? you are right, they are low on cholosterol and thus low on T.

Aging is characterized by constant excretion of glucose like nutrients(magnesium one of them)... And inability to use glucose and cholesterol properly... Progesterone is main hormone in helping body use glucose and cholesterol properly... But if glucose and cholesterol are not in the system Progesterone can't do much to restore order... Healthy individuals have good levels of both hormones in the system... When one is high and other low body runs on adaptation mode... Finasteride makes these guys run in adaptation mode just to save some hair for the sake of other organs like brain... And as soon as body stops having raw materials for hair growth(testosterone/glucose) finasteride stops having positive results in terms of hair...That's why there is a recommendation to take finasteride with lysine/proline two amino acids can replicate the actions of Cholesterol

 

[JoeKool]

For PFS, I've been using pansterone (4 drops on scrotum) and 5a-dhp (15mg)... Is it smart to do both? I immediately felt the pansterone but it has subsided.

Should I only use one to start? Lower 5a-dhp? Stick with It?

600mg Randro too

 

[TubZy]

Yes Progesterone seems to work good with nutrients and hormones that increase blood sugar (dhea/thiamine)

Interesting, DHEA increase blood sugar? How much thiamine? you think the thiamine can help recovery by increasing glucose to the frontal cortex of brain? What about caffeine

 

[mayweatherking]

Aging is characterized by constant excretion of glucose like nutrients(magnesium one of them)... And inability to use glucose and cholesterol properly... Progesterone is main hormone in helping body use glucose and cholesterol properly... But if glucose and cholesterol are not in the system Progesterone can't do much to restore order... Healthy individuals have good levels of both hormones in the system... When one is high and other low body runs on adaptation mode... Finasteride makes these guys run in adaptation mode just to save some hair for the sake of other organs like brain... And as soon as body stops having raw materials for hair growth(testosterone/glucose) finasteride stops having positive results in terms of hair...That's why there is a recommendation to take finasteride with lysine/proline two amino acids can replicate the actions of Cholesterol

Pfs is greatly associated with slow digestion leading to feelings of being full while actually cortisol is spiked and.nothing is getting out.

How do you suggest attacking the issue then? Even preg I think would increase stress just due to the fact that blood sugar has a very poor chance of being properly addressed due to cortisol all over the place.

 

[mayweatherking]

Interesting, DHEA increase blood sugar? How much thiamine? you think the thiamine can help recovery by increasing glucose to the frontal cortex of brain? What about caffeine

Dude what is your current status? You say you are recovered then asking about all this other stuff.. ?

 

[TubZy]

Dude what is your current status? You say you are recovered then asking about all this other stuff.. ?

Everything is logged in the thread bro, you only posted in 1000 times over a 17 page thread, do you not read it? My exact last post in the post finasteride thread talks about blood sugar issues and burning through glycogen stores extremely fast hence my above question on thiamine. Not sure how much more simple it can be to understand.
Post Finasteride

You said you have candida why are you asking about this stuff? You sure have pfs?
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