Prolactin suggested might protect against Toxoplasma G.

Gustav3Y

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The obtained results could indicate the possible protective action of PRL in a host organism infected with Toxoplasma and suggest that a significant increase in the serum PRL level, during pregnancy for instance, might significantly limit the risk of Toxoplasma spreading and could play an important role in natural protection against toxoplasmosis. The mechanism of inhibitory effect of PRL needs further detailed study.





The immunoneuroendocrine network interactions between prolactin (PRL) and the immune system are important because PRL modulates humoral and cellular immune responses in both physiological and pathological situations, as it occurs in parasitic diseases. Protozoa parasites such as Leishmania sp, Toxopasma gondii, Trypanosoma cruzi or Plasmodium falciparum induce inflammation and raise the release of pro-inflammatory cytokines. PRL triggers anti-parasitic activities, in cells of the immune system at multiple levels, either increasing NK cytolytic activities or enhancing phagocytosis and T helper cytokines 1 (Th1) immune responses.


On the contrary, PRL also may promote infections caused by helminthic parasites such as Toxocara canis, or Taenia solium, these parasites possess PRL receptors and could use PRL to increase their growth, movement or reproduction.
 
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LeeLemonoil

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I don’t think there is anything Anti-Peat to that - the thing is that Peat has a slight tendency to overvalue certain aspects of hormesis or sometimes denies it altogether and this forum massively overemphasizes that tendency.

Of course Prolactin is part of a conserved anti-inflammatory or parasitic response.

It gets problematic when such conditions endure and dominate. That’s when stuff like estrogen and prolactin become harmful.

Peats basic idea is that we live in an environment that constantly exposes us to stimuli that provoce such reaponses and that’s why the „Estrogen realm“ of hormesis is the one where today’s people should put their attention to healthwise, to counteract.

And that’s wise.

It doesn’t mean that prolactin has its rightful, useful place in human physiology
 
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Gustav3Y

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Peats basic idea is that we live in an environment that constantly exposes us to stimuli that provoce such reaponses and that’s why the „Estrogen realm“ of hormesis is the one where today’s people should put their attention to healthwise, to counteract.

And that’s wise.

Definitely.
And it is from Peat where initially I heard an explanation for how pathogens can trigger various issues that at surface doctors attribute to nothing but chance, to say the least.

I also made sure to present the counter argument in the same study that claims that PRL can also promote other type of parasitic (helminthic) infections ( even if it may protect from different ones (protozoa)
 
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