Sulcuscentralis
Member
- Joined
- Apr 24, 2017
- Messages
- 625
Th
This! I learned that the hard way. I supplemented with a lot of b1 due to deficiency and overdid it.I think the turnover is quicker if the person is supplementing a lot of B1, so ingesting more from diet or supplementing is necessary.
I'm personally not in favor of using a lot of B1, especially long term. I imagine it would be hard to keep up with the requirements that it increases, such as for potassium , magnesium, manganese, probably lipotropic substances like choline( excessive b1 can cause fat accumulation in the liver without a lot of other b vitamins, due to increased acetyl CoA production in this organ). The organism will surely find a way to balance itself out, but the adaptation may be counter-productive in the long run.