Examastane Sources - Research Chem vs Pills

[Frankdee20]

Purchased some Pansterone and Androsterone again as I had nice effects previously. Looking for a aromatase inhibitor to keep E2 in check.

Wanted to ask the forum members in the United States about whether they trust liquid research chemicals from the U.S. for this medicine, or buy the brand name pills from Alldaychemist in India.

I previously used the liquid version from Blue Sky. Took sporadic doses here and there without complications, but who the hell knows how stable the compound is or whether it was even real or diluted. The brand name XTANE from India fetches 50 dollars.

 

[maillol]

Don't do it. I experienced long term (years) negative effects from taking only a few 12.5 mg doses of pharma exemestane. Even now my estrogen is too low, There are no studies supporting this but I know other members here and on other bodybuilding forums who have experienced the same. There are easier, safer ways to lower estrogen if you really need to.

 

[António Marceli]

Don't do it. I experienced long term (years) negative effects from taking only a few 12.5 mg doses of pharma exemestane. Even now my estrogen is too low, There are no studies supporting this but I know other members here and on other bodybuilding forums who have experienced the same. There are easier, safer ways to lower estrogen if you really need to.

What safer ways would that be? Vitamins adek?

 

[maillol]

First thing I'd go for would be aspirin.

Association of Frequency and Duration of Aspirin Use and Hormone Receptor Status With Breast Cancer Risk

Context Use of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) has been associated with a decrease in the risk of several cancers, including breast cancer. NSAIDs inhibit cyclooxygenase activity and thereby reduce prostaglandin synthesis; prostaglandins stimulate aromatase gene...

jamanetwork.com

Cyclooxygenase inhibitors suppress aromatase expression and activity in breast cancer cells - PubMed

Estradiol is biosynthesized from androgens by the aromatase enzyme complex. Previous studies suggest a strong association between aromatase (CYP19) gene expression and the expression of cyclooxygenase (COX) genes. Our hypothesis is that higher levels of COX-2 expression result in higher levels...

pubmed.ncbi.nlm.nih.gov

 

[ddjd]

I researched this a while back. There's an Indian brand called xtane that's very well regarded. Avoid Pfizer brand, heard lots of bad things

 

[Frankdee20]

What safer ways would that be? Vitamins adek?

Basically, and Aspirin.

 

[António Marceli]

First thing I'd go for would be aspirin.

Association of Frequency and Duration of Aspirin Use and Hormone Receptor Status With Breast Cancer Risk

Context Use of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) has been associated with a decrease in the risk of several cancers, including breast cancer. NSAIDs inhibit cyclooxygenase activity and thereby reduce prostaglandin synthesis; prostaglandins stimulate aromatase gene...

jamanetwork.com

Cyclooxygenase inhibitors suppress aromatase expression and activity in breast cancer cells - PubMed

Estradiol is biosynthesized from androgens by the aromatase enzyme complex. Previous studies suggest a strong association between aromatase (CYP19) gene expression and the expression of cyclooxygenase (COX) genes. Our hypothesis is that higher levels of COX-2 expression result in higher levels...

pubmed.ncbi.nlm.nih.gov

Thanks :)

 

[António Marceli]

Basically, and Aspirin.

Thanks :)

 

[Jessie]

What safer ways would that be? Vitamins adek?

Zinc! High dosage (50mgs) for brief cycles (4-6 weeks) is an excellent way to reel in high E2 levels without going the pharmacological route. A, D, and E are good too, but I think zinc is probably the missing ingredient for a lot of males. Especially hypothyroid males.

Aspirin has been shown to provide decent results too, but I question how effective it would be if the zinc levels aren't optimal. Poor zinc levels have been directly related to bad testosterone to estradiol ratios. It will also upregulate the AR receptors.

 

[Source Code]

I've been using the raw powder from purple panda labs

 

[A.R]

I've been using the raw powder from purple panda labs

What dose have you been using? Any side effects yet? Like another user mentioned, the side effects become more pronounced when you stop using it.

Really horrible stuff ime, and I would never touch again.

 

[Source Code]

a couple of mg every other day, no I haven't experienced any side effects luckily. I have been using it on and off for a couple of years

 

[A.R]

a couple of mg every other day, no I haven't experienced any side effects luckily. I have been using it on and off for a couple of years

Ok

Do you measure it on a scale or do you eye ball it?

 

[Source Code]

i just do a tiny bit on the tip of my pinky, the amount doesn't show up on my scales

 

[A.R]

i just do a tiny bit on the tip of my pinky, the amount doesn't show up on my scales

It’s great that it’s working well for you. Are you taking any hormones also? (Preg/Dhea etc)

 

[Source Code]

atm just a little bit of dhea maybe 5mg or something