1. haidut

    Dietary PUFA (linoleic acid) causes inflammatory bowel disease (IBD)

    The rates of IBD have truly skyrocketed over the last 10-15 years, significantly surpassing the general increase seen in most chronic conditions, especially in people younger than 40. Over the last couple of years, I posted about studies showing artificial colors (e.g. Red 40), silicon dioxide...
  2. haidut

    NSAID drugs, except aspirin, linked to heart failure

    The link between NSAID usage (except aspirin) and heart attacks is not new, but I decided to still post this study due to the fact that it is the first to suggest those non-aspirin NSAID may actually damage the heart themselves rather than cause CVD events indirectly. Notably, once again...
  3. haidut

    Glucocorticoids may increase inflammation in the long run

    Glucocorticoids (both bioidentical and synthetic) are some of the most widely used drugs in the clinical setting, as well as in outpatient treatment for all sorts of ailments - i.e. autoimmune conditions, joint pain, post-operative inflammation, asthma, and even infectious diseases such as...
  4. haidut

    Blocking PUFA/prostaglandins restores metabolism and reverses brain aging

    The bad news for PUFA has been accumulating for decades, yet public health authorities continue to claim that type of fat is "essential". Whatever indirect admissions of the pathological role of PUFA in both chronic and acute/infectious diseases is given to the public, is usually confined to the...
  5. haidut

    Aspirin - A New Osteoporosis Drug

    A study published almost a decade ago made the bold claim that aspirin may be a novel drug for osteoporosis. [Effect of aspirin administration for the treatment of osteoporosis in ovariectomized rat model]. - PubMed - NCBI However, the study did not get much traction and was in fact mocked by...
  6. haidut

    Serotonin / PUFA Drive Migraine

    The role of serotonin in migraines is becoming more recognized every day. Unfortunately, SSRI drugs are still being used to treat migraines, but more recent studies found that serotonin antagonists like cyproheptadine or mianserin are much more effective. The study below found that linoleic...
  7. haidut

    PUFA And MUFA Are Strong Inhibitors Of 5-AR, Saturated Fatty Acids Are Not

    I have posted quite a few studies showing the effects of various fatty acids on estrogen, androgen and glucocorticoid synthesis. This study shows that both PUFA and MUFA are strong inhbitors of 5-AR, with PUFA being the more potent inhibitors and inhibition potency being strongly dependent on...
  8. haidut

    Endotoxin (LPS) Is A Probable Cause For Chronic Fatigue Syndrome (CFS / ME)

    It seems like the bad news about endotoxin (LPS) just don't stop. After the recent studies implicating in many degenerative conditions, and especially Alzheimer, systemic sclerosis, ALS, etc not this study links it to the so-called chronic fatigue syndrome (CFS / ME), which the medical...
  9. haidut

    Endometriosis Is An Estrogen-caused And Estrogen-driven Disease

    Ray has been writing about this for decades. However, the official Wikipedia page still says that the cause of endometriosis is currently unknown and probably involved genetics. Endometriosis - Wikipedia, the free encyclopedia "...The cause is not entirely clear.[2] Risk factors include having...