1. haidut

    NSAID drugs, except aspirin, linked to heart failure

    The link between NSAID usage (except aspirin) and heart attacks is not new, but I decided to still post this study due to the fact that it is the first to suggest those non-aspirin NSAID may actually damage the heart themselves rather than cause CVD events indirectly. Notably, once again...
  2. haidut

    DHT / Progesterone / aspirin treat, cortisol ineffective, PUFA promotes prostate cancer

    A great study, albeit in-vitro, that once again throws into doubt the entire hypothesis behind prostate cancer. First, it proves the key role of PUFA in the genesis and progression of prostate cancer by demonstrating that inhibitors of the COX enzyme (responsible for synthesizing prostaglandins...
  3. Mito

    NSAIDs dampen the cytokine and antibody response to SARS-CoV-2 infection

    Abstract Identifying drugs that regulate severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and its symptoms has been a pressing area of investigation during the coronavirus disease 2019 (COVID-19) pandemic. Nonsteroidal anti-inflammatory drugs (NSAIDs), which are frequently...
  4. Bodhi

    Some "experts"say Anti Inflammatory Drugs Can Enhance Corona Infection

    Some "experts"say anti inflammatory drugs can enhance Corona infection ... Any thoughts on this please ??? I am taking lots of Asprin these days ,could this be a bad idea ??? Anti-inflammatories may aggravate Covid-19, France advises Ibuprofen may aggravate coronavirus says France health...
  5. haidut

    It's Official - Cancer Surgery Drives Metastasis, Aspirin Can Prevent Them

    The appearance of metastases has long been considered one of the most mysterious and important aspects of cancer due to the fact that metastases can occur even in organisms where the primary tumor has been completely removed and the rest of the organism has been completely isolated form the...
  6. haidut

    Glycine May Treat Hearing Issues Caused By NSAID (aspirin?)

    It is common knowledge that several NASID drugs, including aspirin, cause hearing issues at higher doses. This new research found that the mechanism of action is by competition with chloride ions for activation of the hearing protein called prestin. This suggests a possible method of blocking...
  7. Elias

    Risk Of Acute Myocardial Infarction With NSAIDs In Real World Use

    This article appeared in BMJ. Surprisingly, it made front page headline news in our hospital's news section, where I work. Risk of acute myocardial infarction with NSAIDs in real world use: bayesian meta-analysis of individual patient data | The BMJ
  8. haidut

    NSAID Other Than Aspirin Strongly Increase Risk Of Cardiac Arrest, Heart Failure, And Stroke

    It has been know for at least 20 years that taking NSAID drugs other than aspirin increases risk of heart problems. The risk was considered low and even if materialized it was thought it would lead to relatively low grade heart attacks. However, this new study shows that the risk is higher than...
  9. haidut

    Aspirin As A Cure For Sepsis

    If the truly wonder-drug properties of aspirin were considered lacking by some medical authorities, now we can add curing sepsis to that list. Sepsis is the leading cause of death in hospitalized patients, regardless of age, condition, treatment, etc. It is largely considered a lost cause once...
  10. P

    A NSAID (flufenamic Acid)supress The Spread Of The Cancer In Mice

    A medicine used to treat colds could completely stop the spread of cancer "This latest research could pave the way for medical institutions to use flufenamic acid - a much cheaper cold drug - which has unexpectedly been proven to be effective at fighting cancers,"
  11. haidut

    NSAIDs, With The Notable Exception Of Aspirin, Linked To Fatal Kidney Cancer

    Most doctors now routinely recommend ibuprofen, naproxen, acetaminophen, etc instead of aspirin due to some (mostly unfounded) concerns about bleeding caused by by even low-dose aspirin. It has been known for a long time that NSAID (other than aspirin) use increases the risk of heart attacks...
  12. haidut

    Nsaid (aspirin) May Prevent Cancer Cachexia (wasting)

    Another study linking chronic inflammation to cancer and its signature muscle wasting condition known as cachexia. Yet another piece of the puzzle in how aspirin prevents and maybe even treats cancer. This study is also interesting b/c it found that that the current medical opinion vilifying fat...
  13. haidut

    "Some" Aggressive Cancers May Be Treatable By NSAID

    I find it odd that the article says "some" cancers even though JAK is upregulated in virtually all cancers. Also, instead of listing some common non-prescription drugs (NSAID) that are known JAK inhibitors they talk about proprietary drugs used for rheumatoid arthritis...
  14. haidut

    Caffeine protects the gastric mucosa from NSAIDs and alcohol

    The alcohol case is clear and it is well known that it damages the mucosa. The drug used to induce damage was ibuprofen, but I don't see why the results and conclusions would not translate to aspirin as well, thus making an even stronger case for combining aspirin with caffeine. Effective human...
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