visionofstrength
Member
Hi, sm! I've been looking into this since so many viewed the Getting Ripped thread. I think Peat's explanation is that fat is the result, of course, of consuming more calories than you expend - obviously! But let's focus on expending more calories, not consuming less.sunmountain said:Can someone please explain to a lay person (that would be me) why I have gained fat around my middle since peating? Other than stomach sticking out / gut problem. I'm referring to the blubber.
Is it because I'm not burning sugar, or fat? I'm eating both, and a LOT of sugar all day. I do make sure to eat the sugar with gelatin.
just trying to understand.
Thanks
And so, when you first start Peating you will consume more calories, but the effects of expending more calories may not start right away. It's only when you achieve a very high level of CO2 in your body, by a process called "uncoupling respiration", that you start to expend calories at a very high rate. Once you start uncoupling at this high level of CO2, you generate extra heat, and the fat literally melts off of you. It's a true "fat-burning miracle".
Now, Peat's program for achieving this "fat-burning miracle" of uncoupling is pretty simple:
1. Select a diet that minimizes intestinal inflammation and unsaturated fat,
2. Avoid meat stripped of cartilage, and
3. Use anti-inflammatory "uncouplers" to improve the redox balance of your cells.
Surprisingly, it's not just Peat who thinks so, even mainstream science is at last starting to acknowledge that Peat is right about the weight loss or fat-burning miracle that comes from uncoupling:
Journal of Biochemistry said:Mitochondrial uncouplers with an extraordinary dynamic range
Weight gain, leading to obesity, occurs when energy intake consistently exceeds energy expenditure. In principle, obesity can be treated by reducing caloric intake, by increasing expenditure, or by both approaches simultaneously. Current pharmacological therapies using sibutramine or orlistat [1] or, more recently, rimonabant [2] act primarily to reduce energy intake, and energy expenditure has been relatively neglected as a target for obesity therapy [3]. One way to increase energy expenditure is to use uncouplers to weaken the coupling between fuel oxidation and ATP production. Uncouplers work by transporting protons across the mitochondrial inner membrane, short-circuiting the normal pathway of oxidative ATP synthesis driven by proton flow and causing the loss of calories as heat. Uncouplers are usually lipophilic weak acids that pick up a proton, diffuse across the mitochondrial inner membrane into the matrix, deprotonate and then exit as anions before repeating the catalytic cycle.
The notable success of the uncoupler DNP (2,4-dinitrophenol) as a treatment for human obesity in the 1930s provided an important proof-of-concept and showed that the beneficial effect of uncoupling on energy expenditure is not overwhelmed by compensatory increases in caloric intake. The early literature on treatment of humans and previous studies in rats suggest that DNP matches or outperforms modern drug candidates at causing weight loss [1,4–6]. However, the narrow therapeutic window of DNP and other conventional uncouplers led to the abandonment of their official use in treatment of obesity. Increases (3–10-fold) above the minimum effective dose result in too much uncoupling, leading to compromised ATP production, hyperthermia and death. Concern over this narrow therapeutic window was one of the primary reasons that DNP was withdrawn from the market in 1938 [1,5–7].
For uncouplers to work safely, they should cause uncoupling that increases very little as their concentration rises, potentially widening the difference between therapeutic and toxic doses and giving a wide therapeutic window. Knowing which features of uncouplers to manipulate to give the desired wide dynamic range (ratio of concentrations giving maximum and minimum observable uncoupling) is crucial to the rational design of uncouplers that may be safe for use in obesity treatment. In the present study we investigated uncouplers with an extraordinarily wide dynamic range of greater than 106-fold, and analyse the mechanisms by which this is achieved.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267406/