Obi-wan
Member
- Joined
- Mar 16, 2017
- Messages
- 1,120
Drinking Coffee and Cacao Powder plus Cacao butter and Shea butter transdermal are the best in my opinion for Stearic acid
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I would imagine that it would. As a relatively nonpolar lipid you'd think that it would have roughly the same kinetics as vitamin D and androgens, which enter circulation. But one of the main differences is that stearic acid is a substrate for β-oxidation and many acyltransferase enzymes; this means that some of it would probably be metabolized for energy before it gets there, and some other incorporated into structural lipids.does transdermal stearic acid get into circulation? The abstract for the massaged oil in neonates just says "saturated fats" for the coconut oil. It could be that just myristic acid and smaller get past the skin.
You saw that it was a hyperaccumulator, and could concentrate even more selenium that Brazil nuts.@Travis I saw you mention broccoli being a big source of selenium. Do you think very well boiled broccoli would be a good addition to the diet? Or would the boiling to prevent the supposed goitrogenic effects reduce the selenium and essentially make it worthless?
I have received a few reports from people who have been declared to be in "indefinite remission" (not even sure what that means) with a combination of orlistat (mentioned in a few of the studies I posted), aspirin and niacinamide. I think one had lymphoma, another one had breast cancer, and one had prostate cancer.
Reports from where?
Transdermal vs dietary stearic acid....which has a better chance of avoiding β-oxidation/acyltransferase enyzmes and then getting incorporated into structural lipids.stearic acid is a substrate for β-oxidation and many acyltransferase enzymes; this means that some of it would probably be metabolized for energy before it gets there, and some other incorporated into structural lipids.
It's nearly unavoidable, especially if you eat either dairy or leaves. A person eating mostly grains might have issues with this, but most people get enough. It only takes a few milligrams per day for the liver to create enough DHA for the brain; all excessive DHA gets incorporated into peripheral cell membranes, once the capacity of the brain has been exceeded.
I think you'd be fine with the crucifers, and consuming fish is consuming DHA directly—eliminating the very need for α-linolenic acid. Fish also has eicosapentaenoic acid, the other product of α-linolenic acid which becomes a membrane lipid; this is the precursor for the 3-series prostaglandins which have less activity than the 2-series. In a cancer cell culture study that I'd read, prostaglandin E₃ had only ~¹⁄₄ the activity as did prostaglandin E₂. I think α-linolenic acid is one of those near unavoidables: as long as a person eats whole foods, they are getting enough. I think the main issue instead would be the ω−6 fatty displacing α-linolenic acid, perhaps leading the arachidonic acid in the brain and other cell membranes. As lacking clothes and fur at birth, I don't think anyone would take issue with the idea that humans had evolved in the tropics. In warm latitudes, plants produce primarily saturated fatty acids (i.e. coconut, shea, macadamia). As humans had spread from the equator over the millennia they naturally had started consuming the ω−6 fatty acids which, if you will allow me to speculate, caused noise in the endogenous eicosanoid system dominated by 3-series prostaglandins. It's not that they necessarily caused noise in the system through sheer numbers, although they often do and are consumed by some people in great amounts, but that their slightly different structure makes for a more powerful eicosanoid. After the mechanical agricultural revolution followed by seed pressing in temperate climates, the human body simply could not adapt in time—the television media anti-saturated fat campaign induced by Ancel Keys' ignorance certainly didn't help. Now we have prostaglandin E₂ feeding cancers left and right, and we also have prostaglandin D₂ causing hair loss.@Travis As a follow up to this question/response... What are other sources of alpha-linolenic acid? Not that I'm looking to load up on the stuff, but wanting to verify I'm getting some. I can't eat dairy/eggs and dont eat many leaves so just curious as to what are other decent/somewhat peat related sources? I eat broccoli, brussel sprouts, and cod filets a few times a week. Thanks for the help!
Transdermal, because stearic acid can be converted into oleic acid by Δ⁹-desaturase in the liver. Certainly this enzyme exists elsewhere, but probably in the concentrations found in the liver. I also think that the tissues have less metabolic activity than the liver. So taken together, I think transdermal would lead to more unmodified stearic acid in the blood despite the slower route.Transdermal vs dietary stearic acid....which has a better chance of avoiding β-oxidation/acyltransferase enyzmes and then getting incorporated into structural lipids.
Missing a few letters there yourself. Don't forget the edit buttonActually better to use transdermal. Stearic acid will stay as stearic acid where if taken orally some will convert to oleic acid
I have received a few reports from people who have been declared to be in "indefinite remission" (not even sure what that means) with a combination of orlistat (mentioned in a few of the studies I posted), aspirin and niacinamide. I think one had lymphoma, another one had breast cancer, and one had prostate cancer. From what I understand, they do eat fat but just try to limit PUFA intake. With the recent studies on caprylic acid and other SFA completely destroying tumors, I think it is another confirmation that it is just the PUFA that needs to be avoided in cancer patients, not all fat. But regardless of the type of fat, orlistat would block most of the fat absorption anyways. -per Haidut.
I have not tried orlistat, but in my opinion might not be a good idea since I am trying to get Stearic acid into the cell
I don’t know if you can easily get pure stearic acid. It seems USP grade stearic acid is a blend of stearic (C18) acid (min 40%) and palmatic (C16) acid.I mean that pure stearic acid is sold as cosmetic ingredient and it is often made from palm oil.
I use Cocoa butter in the morning and Shea butter at night transdermal. Cocoa powder in my coffee. Tried straight stearic acid but does not work transdermal and still ends up as flakes in my coffee. I agree with @Glassy orlistat is not the way to go