The oil used was oxidized sunflower oil, but I don't see why it would not apply to other PUFA as well. As little as 5% sunflower oil in the diet induced heart damage. Vitamin E (alpha tocopherol) protected the heart, but at higher doses (more than 7,000mg per day) it enhanced the damage. Of course, I don't think anybody would take such a higher dose and even the Shute brothers limited their protocol to about 5,000mg daily.
http://www.ncbi.nlm.nih.gov/pubmed/25497780
http://www.ncbi.nlm.nih.gov/pubmed/25497780