peatpilled
Member
Emodin, the active component of Cascara Sagrada downregulates androgen receptors.
"Emodin treatment resulted in repressing androgen-dependent transactivation of AR by inhibiting AR nuclear translocation."
Source: Emodin down-regulates androgen receptor and inhibits prostate cancer cell growth - PubMed
Interesting- I noticed a significant drop in libido during and after taking Cascara Sagrada.
"Emodin treatment resulted in repressing androgen-dependent transactivation of AR by inhibiting AR nuclear translocation."
Source: Emodin down-regulates androgen receptor and inhibits prostate cancer cell growth - PubMed
Interesting- I noticed a significant drop in libido during and after taking Cascara Sagrada.