histamine

  1. haidut

    Cancer Is A Metabolic Disease, Diet Is Its Drug

    This is perhaps the most stunning article to date I have seen in mainstream media (MSM). For more than 100 years the story has always been that cancer is a genetic disease due to mutations that turn cells into rampant killing machines. Now, one of the bastions of MSM - the mighty "Atlantic" -...
    • haidut
    • Thread
    • arginine asparigine cancer cure diet histamine metabolic disease metabolism methionine nutrition restriction treat
    • Replies: 49
    • Forum: Scientific Studies
  2. P

    Statins May Exert Beneficial Effects Through A Pathway Other Than It's Cholesterol Lowering Action

    Was surprised when saw a study showing statins have positive effects on bones, did a bit of searching and it turned out that it has some positive action,generally, through inhibiting rho kinase, which also is protective against heart disease. Im not promoting statin use at all(for obvious...
    • paymanz
    • Thread
    • aspirin bone health calcitriol cancer cholesterol depression diabetes erectile dysfunction fibrosis histamine hypertension osteocalcin osteoporosis parkinson's rho-kinase salicylates statins taurine vitamin d
    • Replies: 8
    • Forum: Articles & Scientific Studies
  3. haidut

    Estrogen Causes Asthma; Progesterone, T, DHT, And DHEA Are Protective

    Most of the forum members probably know that the incidence of "autoimmune" conditions is much higher in women then in men. This fact gets consistently ignored by doctors working in the field as a mere fluke, or due to "unknown hormonal interactions" which are nonetheless deemed not causative of...
    • haidut
    • Thread
    • asthma autoimmune cause estradiol estrogen histamine inflammation interleukin
    • Replies: 8
    • Forum: Scientific Studies
  4. P

    Carnosine Attenuates Mast Cell Degranulation And Histamine Release Induced By Oxygen-glucose Depriva

    Carnosine attenuates mast cell degranulation and histamine release induced by oxygen-glucose deprivation. - PubMed - NCBI Carnosine (beta-alanyl-histidine) is a naturally occurring dipeptide that has been characterized as a putative hydrophilic antioxidant. The protective function of carnosine...
  5. P

    Antihistamine Effect Of Vitamin C

    Antihistamine effect of supplemental ascorbic acid and neutrophil chemotaxis. - PubMed - NCBI Impact of oral vitamin C on histamine levels and seasickness. - PubMed - NCBI
  6. P

    TNF Alpha

    I probably will edit this post and update it. Magnesium and tnf alpha interaction Elevated concentrations of TNF-alpha are related to low serum magnesium levels in obese subjects. - PubMed - NCBI Adequate zinc intake is necessary for protection against tnf alpha and pufa Zinc nutrition and...
  7. P

    Positive Effect Of H1 Antihistamines On Bone Density

    Anti-histamine Therapy and Bone Mineral Density: Analysis in a Population-Based U.S. Sample Background Histamine may play an important role in bone turnover. The data regarding histamine receptor antagonists (H1RA, H2RA) and bone mineral density in humans are sparse. We examined bone mineral...
  8. P

    Histamine Suppresses Epidermal Keratinocyte Differentiation And Impairs Skin Barrier Function In A H

    Histamine suppresses epidermal keratinocyte differentiation and impairs skin barrier function in a human skin model Abstract Background Defects in keratinocyte differentiation and skin barrier are important features of inflammatory skin diseases like atopic dermatitis. Mast cells and their...
  9. haidut

    Ketotifen May Treat Hashimoto's

    I am posting this study for those people who need an alternative to thyroid hormone treatment. This is a human study, so it is even more relevant for people with Hashimoto's. Given the main effects of ketotifen as a histamine and leukotriene antagonist, as well as some serotonin antagonism it...
    • haidut
    • Thread
    • anti-histamine autoimmune hashimoto's histamine ketotifen thyroiditis treat
    • Replies: 15
    • Forum: Scientific Studies
  10. haidut

    Ketotifen Prevents Skin Aging/wrinkles Due To UV Light

    Meet your new beauty ingredient - ketotifen. UV light exposure is one of the main triggers of visible signs of skin aging and contributes to lipofuscin formation as well. It looks like ketotifen may be able to prevent that damage and given its leukotriene and histamine antagonism it may be a...
    • haidut
    • Thread
    • aging anti-histamine histamine ketotifen mmp mmp inhibitor prevent reverse skin uv uv light wrinkels
    • Replies: 22
    • Forum: Scientific Studies
  11. haidut

    Ketotifen Can Reverse Pancreatic Damage And Improve Digestion

    Many people on the forum have reported struggling with poor digestion, and some have experienced relief by taking digestive enzymes. Peat and many other researchers have written about the connection between poor digestion and virtually all chronic conditions. The pancreas can get damaged by a...
    • haidut
    • Thread
    • allergy anaphylaxis digestion enzymes epinehprine histamine ketotifen pancreas restore shock zaditen
    • Replies: 57
    • Forum: Scientific Studies
  12. raypeatclips

    Magnesium Chloride Relaxes Smooth Muscle. Decreases Histamine Response

    Effect of magnesium chloride on rabbit bronchial smooth muscle. - PubMed - NCBI Ann Emerg Med. 1990 Oct;19(10):1107-12. Effect of magnesium chloride on rabbit bronchial smooth muscle. Spivey WH1, Skobeloff EM, Levin RM. "Magnesium chloride produced dose-dependent relaxation of bronchial...
  13. haidut

    Cyproheptadine - Liquid Serotonin Antagonist For Lab/R&D

    Due to popular demand, we have released the well-known chemical cyproheptadine as a product for R&D use only. I don't think cyproheptadine needs any introduction here, so I have simply provided the Wikipedia links and some relevant links from the forum. Cyproheptadine - Wikipedia Please note...
    • haidut
    • Thread
    • aldosterone cortisol cyproheptadine endorphins estrogen hgh histamine serotonin
    • Replies: 406
    • Forum: IdeaLabs
  14. P

    Theanine Is A Candidate Amino Acid For Pharmacological Stabilization Of Mast Cells

    Theanine is a candidate amino acid for pharmacological stabilization of mast cells. - PubMed - NCBI The increasing occurrences of allergic disorders may be attributed to exposure to environmental factors that contribute to the pathogenesis of allergy. The health benefits of green tea have been...
  15. haidut

    Lisuride Is A Potent Anti-histamine, And Peripheral Serotonin Antagonist

    I posted some threads on treating obesity by inhibiting peripheral synthesis of serotonin, or antagonizing its actions. One drug that could do that is cyproheptadine, however some people gain weight on it due to increased appetite. Other drugs that are effective for obesity are cabergoline and...
  16. haidut

    Serotonin and histamine produce gastric lesions

    If there was any doubt that serotonin and histamine are not good for you hen chronically elevated, here is an older study showing both substances producing gastric lesions in rats. Look in the section "Production of gastric lesions" for details. https://www.jstage.jst.go.jp/article/jp ...
  17. Hugh Johnson

    Lidocaine Demethylates DNA

    Lidocaine time- and dose-dependently demethylates deoxyribonucleic acid in breast cancer cell lines in vitro http://bja.oxfordjournals.org/content/early/2012/04/26/bja.aes128.full I wonder if chronic oral intake could reverse gene methylation.
  18. K

    Histamine And His Role In Sleep/wake And AD(H)D

    Wow, I've been studying histamine for some time, and it's quite interesting, but so hard ! Please correct me if I'm wrong, I'm kind of noob with biology and pubmed, and I'm sure I make mistakes all the time. Histamine in the hypothalamus seems to have some role in regulating sleep wake cycles...
  19. himsahimsa

    Beta-Alanine, Carnosine, Lactate And Histamine

    Beta-alanine is the limiting substrate for the production of Carnosine. Carnosine (not carnitine) is the primary intracellular buffer for lactate. Histidine can take two (at least) metabolic pathways. It can end up as histamine or, if there is a good supply of beta-alanine, the histidine is...
    • himsahimsa
    • Thread
    • amino acid beta-alanine carnosine histamine lactate supplemental
    • Replies: 27
    • Forum: Amino Acids
  20. haidut

    Antihistamines Can Treat Anxiety-based Disorders Like PTSD

    The specific drug studied was diphenhydramine (Benadryl), which Ray Peat recommends for several problems including endotoxin protection and liver support. http://psychcentral.com/news/2013/10/23 ... 61082.html http://www.pnas.org/content/early/2013/ ... l.pdf+html However, I have seen pretty...
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