This is what a functional medicine doc familiar with ALS and other neurological diseases told me when I emailed him. I can’t afford to talk to them for an official consult and I’m not sure if it’s worth it but looking into this a bit I’m starting to believe him after realizing one of the main drivers of that disease is inability to break down acetylcholine
Whatever is happening to me; the breathing is BY FAR the worst thing. Very weak breathing , and constricted airways mimicking asthma. Wheeze etc on exhale though mouth. Tried every asthma med etc. I csn barely get a breath in when laying down it’s so weak. Acetylcholine is a bronchoconstrictior and it can cause major muscle dysfucntion in excess .
So these are some of the symptoms I told him that made him think GWS
My breathing issues started while I was taking multiple acetylcholine increasing supplements - Huperzine and alpha gpc and something else. It was too much at the time. I had a cholinergic crisis where I was salivating like I had rabies ,I had to spit constantly into a bucket. woke up with parlaysis of my right arm and leg that took a couple mins to regain. I stupidly did not make the connection to the supps and kept taking them until finally I couldn’t breathe anymore at all times. At first it was only when I laid down but now it’s constant.
My first thought was it was the acetylcholine doing this and I’ll stop and it’ll go back to normal. Never did. That was last Christmas. I abandoned the thought it was acetylcholine related after a bit since surely it would have returned to normal after stopping all that stuff. Perhaps it’s not so simple.
All my muscles including respiraotry muscles are constantly twitching. Think ALS. They still do. Excess acetylcholine (among other things) can do this. Emg showed no ALS. (All scans showed nothing)
The cheek linings are swollen out in my mouth- which believe are inflamed salivary glands that swoll up on the acetylcholine increasing drugs.
My serotonin is also high- and I’m on Octreotide to lower it. Hasn’t affect the breathing or fasciculations.
I’ve tried cyproheptadine a couple months ago and Benadryl here and there and nothing helps. I need to figure out a way to increase Acetylcholinesterase, becasue it appears either I’m deficient now or something else is preventing the acetylcholine breakdown like GWS .
I need ways to decrease acetylcholine or increase Acetylcholinesterase . I’m discouraged that this may be a permanent deal at this point. Not one second of relieve in over a year. Desperate doesn’t even begin to describe where I am right now.
looking for any advice or thoughts on how to get this acetylcholine issue under control if it’s not too late.
Whatever is happening to me; the breathing is BY FAR the worst thing. Very weak breathing , and constricted airways mimicking asthma. Wheeze etc on exhale though mouth. Tried every asthma med etc. I csn barely get a breath in when laying down it’s so weak. Acetylcholine is a bronchoconstrictior and it can cause major muscle dysfucntion in excess .
So these are some of the symptoms I told him that made him think GWS
My breathing issues started while I was taking multiple acetylcholine increasing supplements - Huperzine and alpha gpc and something else. It was too much at the time. I had a cholinergic crisis where I was salivating like I had rabies ,I had to spit constantly into a bucket. woke up with parlaysis of my right arm and leg that took a couple mins to regain. I stupidly did not make the connection to the supps and kept taking them until finally I couldn’t breathe anymore at all times. At first it was only when I laid down but now it’s constant.
My first thought was it was the acetylcholine doing this and I’ll stop and it’ll go back to normal. Never did. That was last Christmas. I abandoned the thought it was acetylcholine related after a bit since surely it would have returned to normal after stopping all that stuff. Perhaps it’s not so simple.
All my muscles including respiraotry muscles are constantly twitching. Think ALS. They still do. Excess acetylcholine (among other things) can do this. Emg showed no ALS. (All scans showed nothing)
The cheek linings are swollen out in my mouth- which believe are inflamed salivary glands that swoll up on the acetylcholine increasing drugs.
My serotonin is also high- and I’m on Octreotide to lower it. Hasn’t affect the breathing or fasciculations.
I’ve tried cyproheptadine a couple months ago and Benadryl here and there and nothing helps. I need to figure out a way to increase Acetylcholinesterase, becasue it appears either I’m deficient now or something else is preventing the acetylcholine breakdown like GWS .
I need ways to decrease acetylcholine or increase Acetylcholinesterase . I’m discouraged that this may be a permanent deal at this point. Not one second of relieve in over a year. Desperate doesn’t even begin to describe where I am right now.
looking for any advice or thoughts on how to get this acetylcholine issue under control if it’s not too late.