Mauritio
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- Joined
- Feb 26, 2018
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Narirutin is the secon most common flavonoid in orange juice, but is little talked about.
Here are some interesting studies:
1. Anti-depressant effect
- Narirutin produces antidepressant-like effects in a chronic unpredictable mild stress mouse model - PubMed
2. Lowers inflammation via TNFa, NO, COX2 and PGE2
- Narirutin fraction from citrus peels attenuates LPS-stimulated inflammatory response through inhibition of NF-κB and MAPKs activation - PubMed
3. Treats liver steatosis:
- https://www.sciencedirect.com/science/article/pii/S0753332223011411?via=ihub
4. Lowers NLRP3
- Narirutin exerts anti-inflammatory activity by inhibiting NLRP3 inflammasome activation in macrophages - PubMed
5. Lowers LOX-5 and COX2
- Narirutin downregulates lipoxygenase-5 expression and induces G0/G1 arrest in triple-negative breast carcinoma cells - PubMed
6. Helps with asthma via lowering interferon gamma and other cytokines
- Enzyme-Assisted Extraction of Narirutin from Citri Reticulatae Pericarpium and Anti-allergic Asthma Activity - PubMed
Here are some interesting studies:
1. Anti-depressant effect
- Narirutin produces antidepressant-like effects in a chronic unpredictable mild stress mouse model - PubMed
2. Lowers inflammation via TNFa, NO, COX2 and PGE2
- Narirutin fraction from citrus peels attenuates LPS-stimulated inflammatory response through inhibition of NF-κB and MAPKs activation - PubMed
3. Treats liver steatosis:
- https://www.sciencedirect.com/science/article/pii/S0753332223011411?via=ihub
4. Lowers NLRP3
- Narirutin exerts anti-inflammatory activity by inhibiting NLRP3 inflammasome activation in macrophages - PubMed
5. Lowers LOX-5 and COX2
- Narirutin downregulates lipoxygenase-5 expression and induces G0/G1 arrest in triple-negative breast carcinoma cells - PubMed
6. Helps with asthma via lowering interferon gamma and other cytokines
- Enzyme-Assisted Extraction of Narirutin from Citri Reticulatae Pericarpium and Anti-allergic Asthma Activity - PubMed
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