Low Toxin Logs Log - Anti-Vitamin A Diet - Testing out if i have been a Peatard

[youngsinatra]

@youngsinatra B12 and folate are in the blood test.
Ceruloplasmin, B1, B2, and biotin aren't available for me to test.
I don't know what MMA is.
Copper is possible in the next blood test. I've been struggling with peeing lately. Would be interesting to see how the copper values are.

Ah I see.

MMA stands for methylmalonic acid (MMA). If it’s elevated then it means B12 can‘t be used, even when holo-TC and serum B12 are normal or even high. It’s usually due to biotin deficiency.

Do you get these tests for free?

 

[cfeehan]

Hi Orangebear, Itchy skin can be a sign of liver issues. On the nights that you itch try and correlate it with what you ate, was it something particularly inflammatory?

As for not flushing on 100mg... Different brands can have different quality of niacin, I had a brand years ago that gave me a crazy flush at 100 mg, another brand that gave only slight flushing at 100mg. If you upped your dose to 500 mg you'll look like you just baked in the sun for nine hours.

Side quest: don't tell anyone you're going to do the flush, then when it happens just walk into the room and sit down as if you don't know you look like you're actually on fire.

Just wanted to report an interesting piece of info. I'm only 3 days into starting niacin. My understanding from reading @charlie 's dosing chart is that I don't have to worry too much about buffering until I get to 200mg doses or above, so I have started with 100mg capsules.

For the last 3 days, I've had breakfast about 7am and then followed it with the 100mg niacin dose. Have not felt a thing.

But today, I tried making a drink that I'm planning to try as a coffee replacement (working to ditch the decaf) - 1/2 tsp raw honey, 1/4 tsp ACV and warm water.
Had this about 10am and was only a few sips in when the FLUSH came on strong (I really like it).

I was excited to get that milestone on such a small dose. I'm not sure if it just took a few days to build up in my system or if it was adding the vinegar or if it just took my digestion awhile to break open the capsule. I'm going to try 100mg again tomorrow without the ACV drink and see what happens.

 

[brongfogboy]

Just wanted to report an interesting piece of info. I'm only 3 days into starting niacin. My understanding from reading @charlie 's dosing chart is that I don't have to worry too much about buffering until I get to 200mg doses or above, so I have started with 100mg capsules.

For the last 3 days, I've had breakfast about 7am and then followed it with the 100mg niacin dose. Have not felt a thing.

But today, I tried making a drink that I'm planning to try as a coffee replacement (working to ditch the decaf) - 1/2 tsp raw honey, 1/4 tsp ACV and warm water.
Had this about 10am and was only a few sips in when the FLUSH came on strong (I really like it).

I was excited to get that milestone on such a small dose. I'm not sure if it just took a few days to build up in my system or if it was adding the vinegar or if it just took my digestion awhile to break open the capsule. I'm going to try 100mg again tomorrow without the ACV drink and see what happens.

If you had the niacin on an empty stomach I would guess that's what gave you a more intense flush. If you had it after food as you normally would then you may need to suspect you have low stomach acid since the ACV appears to have helped you. Were you on an empty stomach?

 

[Daniel North]

2 new blood tests:

12th March 2024

19th March 2024

Retinol

All blood tests so far:

 

[Daniel North]

Blood test
2nd april 2024

The retinol is starting to show a trend of going down 0,1 points per blood test.

 

[Peater]

Blood test
2nd april 2024

The retinol is starting to show a trend of going down 0,1 points per blood test.

Excellent! Did you notice any symptoms that could be related to 'dumping' vit A from the liver or has it been a smooth process? How are you feeling?

 

[Jabuger]

So according the the toxic bile theory during these peaks in serum retinol you should be feeling like crap am I correct?

And during the troughs you should feel amazing.

would you say your health has matched these peaks and troughs?

 

[Daniel North]

So according the the toxic bile theory during these peaks in serum retinol you should be feeling like crap am I correct?

Spot on
I dont feel like i have been through any "troughs" yet.

How are you feeling?

A bit better than what i felt like when i had 3,5 in retinol.
Feels like it has been on a very stable, energy-lacking sailing that is sloooowly getting better.

 

[ddjd]

I don't see any benefits at all to doing the blood tests. No. 1 they can be wildly inaccurate and no.2 just go on symptoms and how you feel.... It's as simple as
....Do you feel healthier and better on low vit A diet???

 

[Peater]

A bit better than what i felt like when i had 3,5 in retinol.
Feels like it has been on a very stable, energy-lacking sailing that is sloooowly getting better.

That's great, pleased for you!

 

[FitnessMike]

would you update us on how you feel ? Any improvements?

 

[Daniel North]

@FitnessMike @ddjd Yes, i have more energy in general now, than when I started on the diet on the 16th Oct 2023
I had my first jog of the year a couple of days ago.

 

[brongfogboy]

@FitnessMike @ddjd Yes, i have more energy in general now, than when I started on the diet on the 16th Oct 2023
I had my first jog of the year a couple of days ago.

Still following your progress, interested.

 

[Daniel North]

Blood test
18th april

 

[Daniel North]

Blood test
14th of May 2024

My retinol has gone up after starting on vitamin K1. I don't know what this means. Increased detox?
Testosterone is also back to semi-normal.
Interestingly they have updated their range for normal retinol levels. From just being above 0,7 to 1,3-3,5

 

[Daniel North]

I suddenly started to think about "how much retinol do you remove from your body after 1 blood donation?"

With the help from chat GPT, potentially as much as 7%!

It then makes sense that my Retinol levels went so fast down in the period where i donate every 1-3 months. See picture below.

The calculations:

 

[Peater]

Great bit of original research!

I need to start donating again. I stopped when our sacred NHS told me i was an evil granny killer for turning down their kind offer of the barely tested novel therapeutic. But as it's for mercenary purposes I suppose i am ok with it.

 

[Daniel North]

Done.

7% less retinol in my body. If the calculations are correct.

It also now makes sense why I always felt relief in my body right after each blood donation. Yes, i also had less stamina when working out because of the reduced hemoglobin levels, but right after each blood donation, it felt as though my muscles relaxed more. And while I write this, Im starting to feel the same effect. My muscles, especially my back, relaxing more.

 

[ddjd]

@charlie is there a list yet anywhere of things that definitely reduce Vitamin A in the body:

- T3 thyroid
- k2 mk4
- methyl b12
- folinic acid
- lactoferrin (??)
- flush niacin

some ideas...

just trying to think how it might be possible to speed up the process

 

[mosaic01]

I suddenly started to think about "how much retinol do you remove from your body after 1 blood donation?"

With the help from chat GPT, potentially as much as 7%!

Chatbots aren't intelligent like humans are, you only get the reply you specifically ask for. Your question ignored the 350-700 μmol/L value for liver and instead you worked with the 3 μmol/L, giving a completely false result.

1. 3 μmol/L translates to 0.85mg of retinol per liter. Removing 500ml means removing 0.4mg retinol.
2. Liver retinol content is measured in micrograms per gram, and usually is in the range of 100-300 mcg/g, but can be as high as 1000 in western people. 300 mcg/g translates to 450mg retinol in a 1.5kg liver. (That would be 1050 μmol/L).
3. Let's say your liver retinol content is indeed 450mg, then a single blood donation would remove 0.08% relative to the amount stored in the liver.

https://www.sciencedirect.com/science/article/pii/S0022316623026263