DaveFoster
Member
I've been having some conversations with Diokine, who's been a huge help to me, and he made this layout, which I think can benefit some people who are trapped in a cycle of hypothyroidism, high cortisol, adrenaline, serotonin, histamine, and estrogen.
"The effects of unmitigated stress in the body are devastating. A lot of things play into it, but when you start getting into a situation where the body is not able accurately reflect it's current energy stores, or it's not able to manipulate the cellular environment through different nervous tones, big problems become apparent. The shift from an environment characterized by high CO2 levels, efficient respiration, high mineral/H2O flux, and sensitivity of cells to androgens, to one characterized by respiration hampered by histamine and nitric oxide, under the influence of estrogen, cannot be understated. The sicker your cells are, the less you can handle. Pretty soon you get to a point where cells will not respond to thyroid, metabolism falls even further, and the body is primed for all sorts of dis-ease including degenerative nerve issues like MS or ALS, cancer, dementia, etc.
I would say recovery can be fairly swift (most major issues can probably be cleared in around a month, depending on conditions) once cellular respiration starts to produce enough energy to allow the cells to spend much of their time in a cooperative living state, with highly structured water and efficient metabolism. This absolutely requires lowering the influence of histamine and serotonin and consequently estrogen. Some steps you can take to do this are;
- Limiting low blood sugar. Keeping the cells in an environment where if they need fuel on short notice, they're able to get it. This includes large blood sugar drops at night.
- Keeping salt intake high. Through many mechanisms, this can help keep the metabolic machinery moving even in the presence of assault.
- Encourage the turnover of histamine and serotonin. The best thing I've found is bright sunshine. It encourages the activity of MAO and DAO (enzymes that process histamine and serotonin.) Get as much of as it you can.
- Neuromodulatory amino acids like glycine. Be careful on the dosing with things like this (including taurine.) Sometimes less is more, and more is way too much. High doses of things like this are indicated for only very short term.
- Bag breathing/exercises and increasing CO2. This was huge for me, partly because it gave me a lot of opportunity to listen to my body and realize what happens to the nervous tone depending on how I'm breathing. If you allow yourself to get slightly starved for air, and be OK with it, it changes the tone of the sympathetic and parasympathetic nervous systems. You will maybe notice a little sweat breaking out on your forehead as you do this. This is good, it means that the CO2 is doing it's job and cells are expelling water. On that note, if you notice you're not very liable to sweat, and you're urinating a lot, this is a good indication that the cells are not responding very well and metabolism may be low.
- Liver health. The liver is the organ responsible for maintaining blood sugar and other nutrient levels. Learn to listen to it. It can sense glucose, amino acids, salt, and many other things through the hepatoportal system. Concentrate on the feelings in the solar plexus area. You should learn to distinguish between when you need glucose, salt, protein, etc.
Some other things off the top of my head are coconut oil, saturated fats are pro metabolic and can be chemically and electrically "insulating" to the different metabolic processes. 4-6tbsp a day is a good amount. Sauna therapy, encourage lots of water/mineral flux in the cell. Sugar, salt, and sunshine are going to be extremely helpful. I see you're starting some red light therapy, this is excellent. Aspirin can help to oppose the effects of estrogen and histamine, and can consequently lower the influence of serotonin. Use it cautiously, though. Make sure thyroid status is adequate. If your TSH is under 1.5, you probably don't need any supplementation. Over 1.5, a VERY small amount of T4 (<50mcg/day) may be appropriate. I would probably hold off on thyroid supplements until you start to feel damn decent, otherwise it will make things harder. I like to look at pictures of smiling faces in the morning, this is pro-metabolic. If you're tired, sleep.
I've attached a few links to some interviews with Dr. Peat (from KMUD, these series of shows are GOLD by the way,) most of the info I'm presenting here I think would be considered "Classic Peat" as far as the metabolic details are concerned.
Herb Doctors: Autonomic Nervous System (2013)
Herb Doctors: Blood Pressure Regulation Heart Failure and Muscle Atrophy (2012)
Herb Doctors: Digestion and Emotion (NEW 2015)"
I don't believe the links are working, but they can easily be searched.
"The effects of unmitigated stress in the body are devastating. A lot of things play into it, but when you start getting into a situation where the body is not able accurately reflect it's current energy stores, or it's not able to manipulate the cellular environment through different nervous tones, big problems become apparent. The shift from an environment characterized by high CO2 levels, efficient respiration, high mineral/H2O flux, and sensitivity of cells to androgens, to one characterized by respiration hampered by histamine and nitric oxide, under the influence of estrogen, cannot be understated. The sicker your cells are, the less you can handle. Pretty soon you get to a point where cells will not respond to thyroid, metabolism falls even further, and the body is primed for all sorts of dis-ease including degenerative nerve issues like MS or ALS, cancer, dementia, etc.
I would say recovery can be fairly swift (most major issues can probably be cleared in around a month, depending on conditions) once cellular respiration starts to produce enough energy to allow the cells to spend much of their time in a cooperative living state, with highly structured water and efficient metabolism. This absolutely requires lowering the influence of histamine and serotonin and consequently estrogen. Some steps you can take to do this are;
- Limiting low blood sugar. Keeping the cells in an environment where if they need fuel on short notice, they're able to get it. This includes large blood sugar drops at night.
- Keeping salt intake high. Through many mechanisms, this can help keep the metabolic machinery moving even in the presence of assault.
- Encourage the turnover of histamine and serotonin. The best thing I've found is bright sunshine. It encourages the activity of MAO and DAO (enzymes that process histamine and serotonin.) Get as much of as it you can.
- Neuromodulatory amino acids like glycine. Be careful on the dosing with things like this (including taurine.) Sometimes less is more, and more is way too much. High doses of things like this are indicated for only very short term.
- Bag breathing/exercises and increasing CO2. This was huge for me, partly because it gave me a lot of opportunity to listen to my body and realize what happens to the nervous tone depending on how I'm breathing. If you allow yourself to get slightly starved for air, and be OK with it, it changes the tone of the sympathetic and parasympathetic nervous systems. You will maybe notice a little sweat breaking out on your forehead as you do this. This is good, it means that the CO2 is doing it's job and cells are expelling water. On that note, if you notice you're not very liable to sweat, and you're urinating a lot, this is a good indication that the cells are not responding very well and metabolism may be low.
- Liver health. The liver is the organ responsible for maintaining blood sugar and other nutrient levels. Learn to listen to it. It can sense glucose, amino acids, salt, and many other things through the hepatoportal system. Concentrate on the feelings in the solar plexus area. You should learn to distinguish between when you need glucose, salt, protein, etc.
Some other things off the top of my head are coconut oil, saturated fats are pro metabolic and can be chemically and electrically "insulating" to the different metabolic processes. 4-6tbsp a day is a good amount. Sauna therapy, encourage lots of water/mineral flux in the cell. Sugar, salt, and sunshine are going to be extremely helpful. I see you're starting some red light therapy, this is excellent. Aspirin can help to oppose the effects of estrogen and histamine, and can consequently lower the influence of serotonin. Use it cautiously, though. Make sure thyroid status is adequate. If your TSH is under 1.5, you probably don't need any supplementation. Over 1.5, a VERY small amount of T4 (<50mcg/day) may be appropriate. I would probably hold off on thyroid supplements until you start to feel damn decent, otherwise it will make things harder. I like to look at pictures of smiling faces in the morning, this is pro-metabolic. If you're tired, sleep.
I've attached a few links to some interviews with Dr. Peat (from KMUD, these series of shows are GOLD by the way,) most of the info I'm presenting here I think would be considered "Classic Peat" as far as the metabolic details are concerned.
Herb Doctors: Autonomic Nervous System (2013)
Herb Doctors: Blood Pressure Regulation Heart Failure and Muscle Atrophy (2012)
Herb Doctors: Digestion and Emotion (NEW 2015)"
I don't believe the links are working, but they can easily be searched.