1. haidut

    SSRI drugs cause depression/anxiety, blocking serotonin rapidly reverses the latter

    It is hard to come up with a more controversial statement in psychiatry than to say that the blockbuster "antidepressant" drugs not only actually cause depression - the very condition they are supposed to treat- but also anxiety (a separate mental disorder, according to DSM V) on top of that...
  2. haidut

    Blocking serotonin may treat obsessive-compulsive disorder (OCD)

    While the meta-study only reviewed studies about blocking the 5-HT3 receptor, other studies listed below directly implicate the 5-HT1, 5-HT2 and 5-HT7 receptors as well, which strengthens the hypothesis that serotonin (5-HT) as a whole is the driver of OCD. In addition, consider the fact that...
  3. haidut

    Serotonin (5-HT) may drive both schizophrenia and Alzheimer Disease (AD)

    Unbeknownst to most people, psychiatry has started to make a quiet "paradigm shift" in regards to psychotic conditions such as schizophrenia. Namely, after claiming for decades that psychotic states are caused by excessive dopamine levels/activity, psychiatry has now quietly change the official...
  4. haidut

    Cocaine "addiction" May Be Driven By Serotonin

    Another study on addiction and its mechanisms, but this one focuses on cocaine which is the second most highly abused drug after alcohol, at least in the US (excluding weed). This new study shows that blocking the serotonin receptor 7 (5-HT7) blocked the cocaine abuse behavior. This would...
  5. haidut

    Serotonin Antagonists As Treatment For IBD (Chron's UC, Etc)

    It is not common knowledge in research (but not clinical) circles that serotonin is the major cause of the so-called "irritable bowel syndrome" (IBS). As such, there are several large clinical trials using TPH inhibitors to lower serotonin synthesis and thus cure the condition. It is also known...
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