Where Is The Evidence That Saturated Fats ___ Pyruvate Dehydrogenase?

[Mr. God of Cars]

Where/what is the evidence that "Saturated fats activate the pyruvate dehydrogenase enzyme that is essential for the efficient use of glucose, while PUFA block it"?

There's no reference to such statement in the article where this statement was taken from: Regeneration and degeneration - Types of inflammation change with aging

It makes me think Ray Peat's ideas are not fully referenced.

 

[Queequeg]

Enzyme to Know: Pyruvate Dehydrogenase – Functional Performance Systems (FPS)

 

[Mr. God of Cars]

Enzyme to Know: Pyruvate Dehydrogenase – Functional Performance Systems (FPS)

Thanks, but is there also evidence for saturated fats increasing PHD in the rested state [that is, non-exercising state]?

 

[haidut]

Where/what is the evidence that "Saturated fats activate the pyruvate dehydrogenase enzyme that is essential for the efficient use of glucose, while PUFA block it"?

There's no reference to such statement in the article where this statement was taken from: Regeneration and degeneration - Types of inflammation change with aging

It makes me think Ray Peat's ideas are not fully referenced.

Here is one direct study looking at that:
Palmitic Acid (palmitate) Strongly Increases Oxidative Metabolism

 

[Highserotonin90]

From my years of research I seem to have understood that all long chain acids inhibit PDH