Skull of balding Men was discovered to be calcified!

[GorillaHead]

If there are only a few foramens that dump blood from the scalp through the skull, then get some imaging done to verify a restriction of flow. If restricted, have surgery to open them up a bit.

Well i read three arteries are responsible for blood flow to the scalp but i am not 100% sure. There is so much to leaen

 

[ChemHead]

Well i read three arteries are responsible for blood flow to the scalp but i am not 100% sure. There is so much to leaen

It's not just about blood flow to the scalp, it's also about blood flow out of the scalp. If the blood that leads to the scalp can't eventually escape and drain out of the scalp, then there won't be a continuous flow of fresh blood. Have to have a clear circuit.

 

[johnwester130]

hairlosstalk is full of people who regrew hair taking spironolactone

Spironolactone works by blocking cortisol and aldosterone. As a coincidence, it stops testosterone and DHT

What if it only regrew hair by the blocking of cortisol/aldosterone?

There's only one study showing that eplerenone may regrow hair

Mineralocorticoid Receptor Antagonists Stimulate Human Hair Growth ex vivo - PubMed

Whilst topical steroids represent one of the most frequently administered treatments for skin and hair diseases, predominantly based on their glucocorticoid receptor-mediated anti-inflammatory effects, the mineralocorticoid effects of topical steroids have received surprisingly little attention...

pubmed.ncbi.nlm.nih.gov

 

[J.R.K]

Ever considered aldosterone is the cause of calcifcation

Things like spironolactone and eplerenone reverse this

Thanks for the thoughts @johnwester130. I am considering sending some toenails to @haidut for analysis just to get a bit of history on where my hormonal profile is.

 

[aliml]

Calcification is also promoted by prostaglandin D2 (PGD2) and transforming growth factor beta subtypes (TGF-β1 and TGF-β2).

A hypothetical pathogenesis model for androgenic alopecia: clarifying the dihydrotestosterone paradox and rate-limiting recovery factors

Androgenic alopecia, also known as pattern hair loss, is a chronic progressive condition that affects 80% of men and 50% of women throughout a lifetim…

sciencedirect.com

Prostaglandin D2 and Hair Loss + 3 Natural Prostaglandin D2 Inhibitors - Hairguard

Androgenetic Alopecia (AGA), the most common cause of hair loss in men, is a problem that affects millions of people worldwide. And while there are drugs on the market that claim to treat the condition – namely, minoxidil and finasteride – they tend to only cover up the problem as opposed to...

hairguard.com

What is TGF Beta? + Factors that May Inhibit/Increase It - SelfDecode Health

TGF-b might play a role in autoimmune diseases, food intolerances & other diseases. Learn what it does & how to increase your levels.

health.selfdecode.com

 

[GorillaHead]

Calcification is also promoted by prostaglandin D2 (PGD2) and transforming growth factor beta subtypes (TGF-β1 and TGF-β2).

A hypothetical pathogenesis model for androgenic alopecia: clarifying the dihydrotestosterone paradox and rate-limiting recovery factors

Androgenic alopecia, also known as pattern hair loss, is a chronic progressive condition that affects 80% of men and 50% of women throughout a lifetim…

sciencedirect.com

Prostaglandin D2 and Hair Loss + 3 Natural Prostaglandin D2 Inhibitors - Hairguard

Androgenetic Alopecia (AGA), the most common cause of hair loss in men, is a problem that affects millions of people worldwide. And while there are drugs on the market that claim to treat the condition – namely, minoxidil and finasteride – they tend to only cover up the problem as opposed to...

hairguard.com

What is TGF Beta? + Factors that May Inhibit/Increase It - SelfDecode Health

TGF-b might play a role in autoimmune diseases, food intolerances & other diseases. Learn what it does & how to increase your levels.

health.selfdecode.com

Any of you guys know why he says baldness was most prominent in people with “luxuriant crop of hair” in the original link i shared. Why would he say baldness was the most prominent in people with lots of hair?

 

[RealNeat]

Lol it would need to be controlled. But lets seriously ask ourselves how much does this this observation have. We need more info before we say its impossible to stop the cause. We obviously can side step with androgens but the cause of what causes the androgens to rise in local tissue is yet to be elucidated and if its because these foramens get pinched then ****

I hate to repeat myself but using other substances (like boron, selenium, magnesium and/ or iodine) to displace fluoride would have at least some "de-calsifying" effect on bone. The bone will become more durable and regain its ability to be somewhat bendable as opposed to calcified and prone to fracture.

Most people in the US megadose fluoride. I wonder if people with fluorosis have more baldness?

Fluorine-induced apoptosis and lipid peroxidation in human hair follicles in vitro - PubMed

Fluoride is an essential trace element for human body; however, exposure to high amounts of fluoride has been documented to be correlated with an increasing risk of hair loss. To date, little is known about the mechanism(s) of how fluoride affects hair follicles. Here, we demonstrated that...

pubmed.ncbi.nlm.nih.gov

 

[GorillaHead]

I hate to repeat myself but using other substances (like boron, magnesium and/ or iodine) to displace fluoride would have at least some "de-calsifying" effect on bone. The bone will become more durable and regain its ability to be somewhat bendable as opposed to calcified and prone to fracture.

Most people in the US megadose fluoride. I wonder if people with fluorosis have more baldness?

Are u saying people have too much fluroide cause in 1917 when this observation was made Fluoride was not that common in peoples system

 

[RealNeat]

Are u saying people have too much fluroide cause in 1917 when this observation was made Fluoride was not that common in peoples system

I'm sure there was also less hair loss

1917

Howard Field CHAPPELL, of New York: "Manufacture of hydrofluoric acid from silicon fluorid", US Patent 1,244,032; filed April 17, 1917; pat. Oct. 23, 1917

Robert M. CATLIN, assignor to Catlin Shale Products Company, of Wilmington Del.: "Process of making hydrogen fluorid", US Patent 1,293,703; filed June 9, 1917; pat. Feb. 11, 1919

Hydrogen Fluoride ( Hydrofluoric Acid )

"Hydrogen fluoride is used to make refrigerants, herbicides, pharmaceuticals, high-octane gasoline, aluminum, plastics, electrical components, and fluorescent light bulbs. Sixty percent of the hydrogenfluoride used in manufacturing is for processes to make refrigerants. Hydrogen fluoride is also used for etching glass and metal." - CDC​

 

[GorillaHead]

I'm sure there was also less hair loss

True but these guys were bald. I am not saying you are false or wrong. Its something to consider. I want verification of this observation. I am gonna try to see who deals with dead bodies and donations of skulls and if we can get 30 data points of peoples foramens and balding status before their death

 

[RealNeat]

True but these guys were bald. I am not saying you are false or wrong. Its something to consider. I want verification of this observation. I am gonna try to see who deals with dead bodies and donations of skulls and if we can get 30 data points of peoples foramens and balding status before their death

I'm not saying it's the only factor but besides what has already been mentioned here with hormones it's another verified way of calcification that can be reversed.

 

[GorillaHead]

I'm not saying it's the only factor but besides what has already been mentioned here with hormones it's another verified way of calcification that can be reversed.

Ive read reports of people reversing calcification in their veins or arteries. But no one regrowing hair. If this is the only issue. I would assume perhaps all they need to do is microneedle and bam the growth is back.

 

[RealNeat]

Ive read reports of people reversing calcification in their veins or arteries. But no one regrowing hair. If this is the only issue. I would assume perhaps all they need to do is microneedle and bam the growth is back.

I think people focus on reversing calcification in soft tissues and there is some overlap of substances for bone but unless an emphasis is put on it (reversing bone calcification) I don't think it will be as effective.

 

[Xemnoraq]

I hate to repeat myself but using other substances (like boron, selenium, magnesium and/ or iodine) to displace fluoride would have at least some "de-calsifying" effect on bone. The bone will become more durable and regain its ability to be somewhat bendable as opposed to calcified and prone to fracture.

Most people in the US megadose fluoride. I wonder if people with fluorosis have more baldness?

Fluorine-induced apoptosis and lipid peroxidation in human hair follicles in vitro - PubMed

Fluoride is an essential trace element for human body; however, exposure to high amounts of fluoride has been documented to be correlated with an increasing risk of hair loss. To date, little is known about the mechanism(s) of how fluoride affects hair follicles. Here, we demonstrated that...

pubmed.ncbi.nlm.nih.gov

Im also under the assumption that fluoride plays a huge role in the calcification process, interested to know more

 

[Xemnoraq]

Has anyone ever seen this publication.

BALDNESS AND CALCIFICATION OF THE "IVORY DOME"

To the Editor:— Some questions concerning baldness which were raised by Dr. Ballenger's comments in The Journal, June 27, may be answered by observations which I made while serving as technician in gross anatomy at the College of Medicine of the University of Illinois (1916-1917). I then had...

jamanetwork.com

Apparently the skull has a spongy layer and this has blood flow going through it and those who went bald incidentally had it calcified.

If this is true it throws alot of shade on those people who think its calcification of the skin tissue because I swear I have read people claim When they massage their scalps they can hear the breakup of calcification which is hilarious.

So it seems the calcification is perhaps actually truly occurring just now where we thought curious how we would remedy or prevent this. Perhaps lack of blood flow itself is not enough to cause balding but the hormone cascade gets triggered due to inadequate blood flow but technically the hair could still he sustained ?

Added image for refrence. The diploe is calcifying or more specifically the opening holes in the skull the foramens are narrowing. Soft tissue calcification reversal is possible and has been exhibited but how does one reverse calcification of the bone. Perhaps the solutions is a procedure that drills or sands down bone of our skulls. This literally would explain why no one has seen benefit using anti calcification protocols

Interesting post man! One thing for hairloss that i do actually have a fair amount of faith in is full scalp massages. Its funny you mention people hearing the calcium break or crunch when the massage their scalp because theres been many occasions while doimg scalp massage and i hear a loud crunch like rocks grinding almost, its very strange it freaked me out a couple times, sounds almost like something snapping.

I will say this about scalp massage, sometimes when i get really stressed i feel my whole head not just my scalp tense up and even my skin on my face feels tight but not in a good way, everything feels swollen and stiff, ive noticed a scalp massage really loosens everything up and has a similar feeling to thyroid or a metabolic increase, my ears get red and my face gets more color into it, it feels like the skin on my head can breath again and isnt suffocating.

Ive noticed that specifically in spots where i have no hair or where its thinning it actually genuinely hurts to massage it because it feels so stiff and fibrotic, as opposed to massaging the sides and back where i have plenty of hair. Ive noticed that its better to do a full scalp massage vs just the spots where its completely bald, a full scalp massage feels like it increases the metabolic rate of the area, it feels almost like youre waking up dead tissue or bringing life back into it, i cant say forsure wheather it regrows hair, but even if it doesnt it definetelt has a noticible positive effect and this is what Ray said, i do notice some small hairs sprouting up in the areas where i thoroughly massage (unless thats just hair that was already there regrowing after falling out)

I dont think scalp massage alone is enough to regrow hair but i think alongside the right diet, lifestyle and maybe supplement / treatment it can really help rev up the metabolic area or where hair is gone,

If i had a good supplement like haiduts solban or some good topical caffeine, vitamin D or progesterone i would apply on the topicals and then do a scalp massage and really get it into the bald and thinning areas

This post you made though is really interesting and its a new perspective on balding i havent really seen yet, we should look into it more, it could explain why people havent had much luck with topical supplements vs orals (minus minoxidil)

 

[Richiebogie]

Any of you guys know why he says baldness was most prominent in people with “luxuriant crop of hair” in the original link i shared. Why would he say baldness was the most prominent in people with lots of hair?

I think he was saying that blood vessels pass through small foramens in the skull which can be seen most prominently in corpses with luxuriant hair…

These have been closed or narrowed in balding corpses…

BALDNESS AND CALCIFICATION OF THE IVORY DOME, Journal of the American Medical Association, July 18 1942
To the Editor:— Some questions concerning baldness which were raised by Dr. Ballenger's comments in The Journal, June 27, may be answered by observations which I made while serving as technician in gross anatomy at the College of Medicine of the University of Illinois (1916-1917). I then had occasion to remove the brains of about 80 cadavers for separate use in the neurology classes and incidentally noted a seemingly obvious relation between the blood (vessel) supply to the scalp and the quantity of hair. Baldness occurred in persons in whom calcification of the skull bones apparently had not only firmly knitted the cranial sutures but also closed or narrowed various small foramens through which blood vessels pass, most prominently in persons with a luxuriant crop of hair. These blood vessels are mainly veins which normally communicate with the diploic veins in the spongy tissue of the skull bones but which are evidently pinched off by calcification* of the foramens. Various stages of this process of impairing the blood circulation of the scalp could be observed. This, then, not only explains why baldness occurs but also why men are more likely to become bald than women, since bone growth or calcification is generally greater in males than in females. Obviously “hair tonics” or vitamins are not likely to restore a blood circulation through what has practically become “solid ivory”. Moreover, one wonders whether the promotion of a higher calcium intake among adults may not eventually increase the incidence of baldness and the sales of its vaunted remedies. Frederick Hoelzel, Chicago

* the original has “calification”