Hi all! Returning here in hopes I may get a little insight on how to dose Progest-e for ongoing estrogen issuesâfibroids, polyps, breakthrough bleeding and short/irregular periods. I have experimented on both NDT (Tyromax) and Progest-e on and offâcurrently taking a grain of NDT and the maintenance dose of 3 drops of Progest-e during the luteal phase⊠Doesnât seem to be cutting it as I have been experiencing breakthrough bleeding again and my period came a week early this last time. I always feel good on the larger loading dose of Progest-e but i thought maybe the NDT would balance it all out and I could only do the minimum and mimic my cycle. Im upping my dose again but am conflicted on info out there on whether to use it continually or cycle it as Iâve read RP says itâs important to take a break as not to overload the liver. For context I am 38, no kids and hoping to protect whatever fertility I have left. I eat pretty Peaty but need to start the carrot salad again, consistency is always the issue. Other supps include; vit k, aspirin, b spectrum, shilajit, egg shell calcium and mag bicarbonate. I guess my ultimate question is should I continuously take larger amounts of Progest-e since I may be considered a more severe case but for how long? If I am still experiencing a period w continual use am I still ovulating, what might that mean? Thanks in advance for any help!