How To Reduce Serotonin

[Constatine]

Thanks for your thoughts on this. Would watching your life through a movie be such a bad thing? I have sometimes heard people exclaim that they feel like they are in a movie when they are having a great time and enjoying themselves thoroughly. Or maybe there is a distinction between life feeling like a movie and feeling like you are looking through a movie? Would you describe high serotonin as having a depersonalizing effect?

Yes high serotonin is depersonalizing. It also seems to make one less aware of various aspects in his/her surroundings. It's hard to describe but if I'm ever consuming a lot of trypotphan and then take a serotonin antagonist I suddenly realize things I missed before. Serotonin puts me in a daze.

 

[Constatine]

Just dont eat muscle meat pretty much?

Or milk unfortunately

 

[PUTFOT]

Or milk unfortunately

Why no milk?

 

[Constatine]

Why no milk?

It's high in trypotophan, but taking bcaa's and tryosine with it will negate this.

 

[PUTFOT]

It's high in trypotophan, but taking bcaa's and tryosine with it will negate this.

How about taking 5-10g of gelatin?

How much total gelatin should be consumed a day?

 

[Constatine]

How about taking 5-10g of gelatin?

How much total gelatin should be consumed a day?

It is normal to consume 80g gelatin a day, however it is safe to go much higher than this. Gelatin does counter some of serotonin's inflammatory properties, however it does not prevent trypotophan absorption and you'll still likely suffer from other negative effects of serotonin. Theoretically the calcium in milk is supposed to reduce serotonin production but there are not studies showing this and milk still gives me signs of increase serotonin whenever I drink it (as well as estrogen signs). Certain cheeses and eggs are also high in trypotophan, in fact most peaters seem to adopt a diet higher in trypotophan than before. These foods might still be good for you but it is best to reduce their absorption again via bcaa's and tryosine. They should be taken together as bcaa's will lower dopamine too unless you take tryosine with it.

 

[Constatine]

Do dopamine agonist / serotonin antagonist drugs have a positive effect after cessation (increased baseline dopamine and dopamine receptors and decreased baseline serotonin and serotonin receptors)?

To the best of my knowledge a dopamine agonist will lower dopamine receptors. However this effect is negligible compared to how much porn and masturbation (and even too much sex) downregulate receptors. If you avoid these activities your receptors will still upregulate even on a dopamine agonist (depending on how strong the agonist is). Serotonin agonists seem to actually downregulate serotonin receptors suggesting that increases in serotonin create a positive feedback loop which is bad. DHT also lowers most serotonin receptors but increases the good ones.

 

[Sucrates]

Calcium will lower the amount of tryptophan converted to serotonin from the diet.

 

[dookie]

Can lower serotonin:
Thyroid/t3
Aspirin
Caffeine
Charcoal
Carrots
Bamboo shoots
Salt
Sugar
Progesterone
Antibiotics
Dopamine
Phenylalanine
Taurine
Glycine/gelatin
Tyrosine
Cyproheptadine/ periactin
Tianeptine
Bromocriptine
Vit d
Calcium
Pregnenolone 30-50mg a day
Phenibut
BCAA's
Ondansetron/ zofran
Lysine
Ginger
LSD
Niacinamide
Benadryl
Agmatine
Co2
Methylene Blue
Adequate protein
Acetazolamide
DMT
L-theanine
Black tea
Psilocybin mushrooms
Lisuride
Zinc
Medium and short chain fatty acids

Can increase serotonin;
Hypothyroidism
PUFAs
Starches and fibres
Too much b6
Wheat based foods
Anything that irritates bowels
Sunburn
Long term starvation
Endotoxin/ inflammation of intestine
Bananas, tomatoes, pineapple
Light deficiency
High Tryptophan
Low testosterone
High Nitric Oxide levels
Elevated cortisol
Protein deficiency
Too much water
MDMA
Whey protein
Estrogen

Signs of high serotonin;
Loose bowels
Autism
IBS
Lots of sweating
Anxiety
Nauseousness
Insomnia
Teeth grinding
Reduced appetite for salt
Asthma
Anorexia
Depression
High blood pressure
Irritability
Aggression

This list is both interesting, but also way off on some things.

Where have you seen that methylene blue can lower serotonin? Methylene blue is known to be able to induce serotonin syndrome.

Also, please provide references for agmatine, charcoal, carrot, bamboo shoots lowering serotonin.

 

[Sucrates]

This list is both interesting, but also way off on some things.

Where have you seen that methylene blue can lower serotonin? Methylene blue is known to be able to induce serotonin syndrome.

Also, please provide references for agmatine, charcoal, carrot, bamboo shoots lowering serotonin.

It's not my list and I'm not going to look for references, but charcoal would be very easy to find and I think the effects of MB on serotonin are dose dependent.

 

[Quality]

Calcium will lower the amount of tryptophan converted to serotonin from the diet.

Link?
As for the list of serotonin lowering compounds I know the list is not yours, but theres alot of none-sense in the list, look agmatine up @ examine.com for example.

 

[Sucrates]

Link?
As for the list of serotonin lowering compounds I know the list is not yours, but theres alot of none-sense in the list, look agmatine up @ examine.com for example.

I don't have a link on calcium but it affects the conversion to niacin vs serotonin. You can see the effect indirectly by looking at the effect of calcium on prolactin and prolactin on serotonin.
I'm not familiar with agmatine, and I'm not sure what the examine article is actually saying about it's effects on serotonin. Effects on plasma serotonin or Tph might give a clearer picture.

 

[Orion]

I don't have a link on calcium but it affects the conversion to niacin vs serotonin.

I recently listened to a RP interview, where he confirmed the above. Milk calcium converts tryptophan to niacin pathways.

 

[Quality]

I don't have a link on calcium but it affects the conversion to niacin vs serotonin. You can see the effect indirectly by looking at the effect of calcium on prolactin and prolactin on serotonin.
I'm not familiar with agmatine, and I'm not sure what the examine article is actually saying about it's effects on serotonin. Effects on plasma serotonin or Tph might give a clearer picture.

Also wheres the link of calcium affecting prolactin?
Well have a look at examine then... even posted a link.
Theres too many people on the internet just claiming things, no backup..

 

[Quality]

I recently listened to a RP interview, where he confirmed the above. Milk calcium converts tryptophan to niacin pathways.

Did he assume this or has this been scientifically proven?
I agree with peat saying that excessive serotonin in general is a bad thing, but theres much more at play.

 

[Sucrates]

I recently listened to a RP interview, where he confirmed the above. Milk calcium converts tryptophan to niacin pathways.

I spent hours trying to verify that one day and then lost the relevant bookmarks.

 

[Orion]

I spent hours trying to verify that one day and then lost the relevant bookmarks.

This thread may be helpful, https://raypeatforum.com/community/threads/milk-calcium-and-the-tryptophan-serotonin-pathway.6015/

 

[Orion]

This thread may be helpful, Milk calcium and the tryptophan-serotonin pathway

No time to read right now, this might have some info: Nutritional Aspect of Tryptophan Metabolism

 

[Quality]

This thread may be helpful, Milk calcium and the tryptophan-serotonin pathway

Clicked on the link, no scientific studies included in the thread though :S
edit: ill have a look at the link you posted later :) cheers for that

 

[Orion]

Clicked on the link, no scientific studies included in the thread though :S
edit: ill have a look at the link you posted later :) cheers for that

Thinking if those aren't helpful maybe a email to RP, see if he can provide some studies. I think he still responds to inquiries, not sure of his email though.