I have been reading about pancreatitis on the boards and the interweb and am left quite confused. Haidut posted a study which blames serotonin for acute pancreatitis. Another study I found, supports this. However, serotonin is needed (it seems) for insulin production.
My understanding is that normally digestive enzymes are produced by the pancreas are not active until they reach the small intestine. In pancreatitis, they are ativating in the pancreas causing damage to the tissue which (stupidly?) isn't designd to withstand the enzyme(s). Does anyone know if this is accurate? What is causing it to activate? How can we stop the premature activation of protease (without causing insulin resistance or diabetes)? Does anyone have personal experience or a very good grasp of all aspects of this disease?
Because I am not wanting to activate the production of protease (until this passes), I am feeding low protein diet (small amount chicken breast with a lot of white rice). I would normally not give them carbs because it isn't part of their natural diet. If I am feeing carbs, adequate insulin production must be allowed so I'm nervous to block serotonin production.
??? what to do???
The one patient is young and adorable, and very sweet and he wants to survive this! He may have "microvascular hepatic displasia" as well as pancreatitis and chronic liver disease can be a contributing factor of pancreatitis (though the mechanism has never been explained to me). He has been having seizures that some say are related to the liver condition and some say are unrelated.
It's all overwhelming for my little brain.
My understanding is that normally digestive enzymes are produced by the pancreas are not active until they reach the small intestine. In pancreatitis, they are ativating in the pancreas causing damage to the tissue which (stupidly?) isn't designd to withstand the enzyme(s). Does anyone know if this is accurate? What is causing it to activate? How can we stop the premature activation of protease (without causing insulin resistance or diabetes)? Does anyone have personal experience or a very good grasp of all aspects of this disease?
Because I am not wanting to activate the production of protease (until this passes), I am feeding low protein diet (small amount chicken breast with a lot of white rice). I would normally not give them carbs because it isn't part of their natural diet. If I am feeing carbs, adequate insulin production must be allowed so I'm nervous to block serotonin production.
??? what to do???
The one patient is young and adorable, and very sweet and he wants to survive this! He may have "microvascular hepatic displasia" as well as pancreatitis and chronic liver disease can be a contributing factor of pancreatitis (though the mechanism has never been explained to me). He has been having seizures that some say are related to the liver condition and some say are unrelated.
It's all overwhelming for my little brain.