Well, if I had cancer, I would avoid any growth factors (insulin, sugar, protein) like the plague, probably fast/do gerson diet and allow my immune system to get rid of those junk cells. Yeah my ketones would be high, good, they aren't growth substrates for cancer. Activating PDH is not a cancer cure, its an anabolic pathway for normal healthy cells, irrelevant in the whole body context of cancer.
ALL cancer cells have downregulated PDH and upregulated PDK. That is why they cannot metabolize glucose and are stuck in glycolysis. The drug DCA is a PDK inhibitor and restores proper PDH activity. Cancer cells also prefer to metabolize fat, and inhibiting this supply of fat to cancer cells is therapeutic.
Inhibiting Lipolysis May Treat / Cure Cancer
Insulin is one if one of the endogenous inhibitors of lipolysis and also of fatty acid oxidation. In a healthy person it is probably not good to inject extra insulin but in a person with cancer who is stuck in ketosis insulin can be a very valuable tool. The idea should not be to kill cancer cells but restore them back to normal activity. So, (proper) anabolic agents are actually quite helpful despite the mainstream view on restricting. Estrogen is anabolic in a BAD way and it is also a de-differentiating hormone. Progesterone, DHEA, T, DHT, etc are beneficial precisely because they are anabolic. Do you know synthetic DHT versions like Drostanolone have been approved by FDA since 1950s for treating (breast) cancer?