TruffleGnocchi
Member
An older person I know has non-functioning testosterone production, zero production from balls. I got him some testosterone, different esters, will recommend using shorter esters daily but bought longer esters if he will insist on not doing daily injections. Also got him exemestene.
My question if anyone has experience or thoughts on this: would it be better for him to take a low dose exemestene right away with the first dose of testosterone he takes, or would it be better to try testosterone first, get it up to 700-1000ng/dl, then only if he feels off or has side-effects, take exemestene?
Since he is an older gentleman, I am worried he will have a significant risk of cancer from conversion to estrogen, and maybe will not recognise the effects of estrogen since he never took testosterone and now has been for some years with no production at all. Also he is a bit overweight and a bit bloated, judging from appearance.
It has been a challenge convincing him that taking testosterone is good for him and will give him at least some of his life back, if he gets side-effects from estrogen I worry he will never want to try testosterone again. In my country there is no such thing as replacement. There are a few new clinics only in the capital city, but that is like a whole new thing here, compared to USA. Doctors will probably advice against it or say it is not needed from my experience with the medical system in this country. At the same time I dont want to unnecessarily give him exemestene and maybe give him unkown side-effects or reduce the benefits of testosterone injections/replacement.
I know shorter esters and higher injection frequency produces more stable levels, and injecting it subcutaneously makes it absorb more gradually. Also is it more likely for testosterone to aromatise when injected into the fat? Bodybuilders say it reduces conversion since it doesnt produce spikes compared to injecting into a muscle, but I'm thinking since aromatase enzyme is produced in the fat, and he is slightly but visibly overweight (not morbidly obese), would IM injections actually result in less conversion.
Also still havent been able to source DHT in Europe. So that is not an option, at least at this time unfortunately.
Any thoughts or experiences are appreciated. Not looking for medical advice.
My question if anyone has experience or thoughts on this: would it be better for him to take a low dose exemestene right away with the first dose of testosterone he takes, or would it be better to try testosterone first, get it up to 700-1000ng/dl, then only if he feels off or has side-effects, take exemestene?
Since he is an older gentleman, I am worried he will have a significant risk of cancer from conversion to estrogen, and maybe will not recognise the effects of estrogen since he never took testosterone and now has been for some years with no production at all. Also he is a bit overweight and a bit bloated, judging from appearance.
It has been a challenge convincing him that taking testosterone is good for him and will give him at least some of his life back, if he gets side-effects from estrogen I worry he will never want to try testosterone again. In my country there is no such thing as replacement. There are a few new clinics only in the capital city, but that is like a whole new thing here, compared to USA. Doctors will probably advice against it or say it is not needed from my experience with the medical system in this country. At the same time I dont want to unnecessarily give him exemestene and maybe give him unkown side-effects or reduce the benefits of testosterone injections/replacement.
I know shorter esters and higher injection frequency produces more stable levels, and injecting it subcutaneously makes it absorb more gradually. Also is it more likely for testosterone to aromatise when injected into the fat? Bodybuilders say it reduces conversion since it doesnt produce spikes compared to injecting into a muscle, but I'm thinking since aromatase enzyme is produced in the fat, and he is slightly but visibly overweight (not morbidly obese), would IM injections actually result in less conversion.
Also still havent been able to source DHT in Europe. So that is not an option, at least at this time unfortunately.
Any thoughts or experiences are appreciated. Not looking for medical advice.