Interesting article.. I was curious anyones good or bad experience with 11 keto dht? Human studies with supplementing it are lacking. An androgen found in fish but also produced by the gonads clearly and potently
“Expression of cytochrome P450 and 11β-hydroxysteroid dehydrogenase types 1 and 2 (key enzymes involved in the synthesis of 11-KT) were investigated in human gonads. The production of 11-KT was investigated in Leydig cells. Plasma concentrations of testosterone and 11-KT were measured in 10 women and 10 men of reproductive age. Investigation of its properties was performed using breast cancer-derived MCF-7 cells.”
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The current study indicates that 11-KT is produced in the gonads and represents a major androgen in human. It can potentially serve as a nonaromatizable androgen.
@haidut @Hans
11-Ketotestosterone Is a Major Androgen Produced in Human Gonads
Context:. 11-ketotestosterone (11-KT) is a novel class of active androgen. However, the detail of its synthesis remains unknown for humans.Objective:. The objec
academic.oup.com
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The current study indicates that 11-KT is produced in the gonads and represents a major androgen in human. It can potentially serve as a nonaromatizable androgen.
@haidut @Hans