dhea-s

  1. EnergeticLeo

    High DHEA, low T, 20s male; Help with blood work interpretation.

    I'm a bit confused as to whether I would benefit from a progesterone + DHEA supplement. Maybe 20-50 mg progesterone + 2-5 mg DHEA (inspired by Structural Requirements For An Optimal Anti-Catabolic Steroid). I'm thinking such a supplement, especially progesterone, could take the stress of the...
  2. Mauritio

    Long term DHEA supplementation doubles androgens and progesterone in males

    I'm not sure if this study has been posted before , at least I haven found anything under the "DHEA" tag. Anyways, it's always good to have more in vivo evidence for peaty substances and what they do in real life. This study gave aging men with partial androgen deficiency (58-69)the "low dose"...
    • Mauritio
    • Thread
    • allopregnanolone androgens dhea dhea-s progesterone steroid steroid hormones testosterone
    • Replies: 28
    • Forum: Scientific Studies
  3. E

    If Anyone Is Interested I'll Be Sharing COA Of Douglas Labs Pregnenolone

    COA attached
  4. haidut

    DHEA-S Completely Prevents Breast Cancer Metastasis Due To Estrogen

    A great new study that debunks several myths related to DHEA. One of those myths is that when used in physiological doses DHEA can increase risk of estrogen-positive cancers, especially breast cancer. Another myth is that declining DHEA levels seen with advancing age are simply a consequence of...
    • haidut
    • Thread
    • block breast cancer cancer colon cancer dhea dhea-s gastric cancer lung cancer prevent treat
    • Replies: 5
    • Forum: Scientific Studies
  5. haidut

    The (in)famous Condition “chemo Brain” May Be Simply A State Of Low DHEA

    The condition known as “chemobrain” is notorious among cancer survivors and many other patients undergoing toxic interventions with chemotherapy and may affect up to 85% of cancer patients. It amounts to severe cognitive dysfunction, memory problems, and even personality changes that result in...
    • haidut
    • Thread
    • cancer chemo brain chemobrain chemotherapy cognition cognitive dysfunction cognitive impairment dementia dhea dhea-s low memory neurosteroid radiation surgery
    • Replies: 0
    • Forum: Scientific Studies
  6. haidut

    DHEA As A Cure For Cancer

    A fascinating study, which highlights once again not only the role of one of the "youth" steroids in human health but also demonstrates that the protective/therapeutic mechanisms of DHEA against cancer are due to increase in metabolism and ROS generation. The primary restrictive mechanism on ROS...
    • haidut
    • Thread
    • cancer cure dhea dhea-s g6pd g6pdh metabolism ros suppression treatment tumor
    • Replies: 63
    • Forum: Scientific Studies
  7. haidut

    Acetaminophen (Tylenol) Depletes DHEA-S And Other Sulfated Steroids

    It is well-known that in animal studies acetaminophen has a potent anti-androgenic and feminizing effect. In some animal models it also reliably causes autism-like symptoms. Given its widespread use and heavy marketing by hospitals, especially to pregnant women (due to its lack of effect on...
    • haidut
    • Thread
    • acetaminophen androgens decrease dhea-s pregnenolone sulfate steroids sulfated tylenol
    • Replies: 18
    • Forum: Scientific Studies
  8. haidut

    Even A Slight Increase In Estrogen Strongly Decreases DHEA Levels

    I posted a few studies in the past revealing that in old age (and menopause) the levels of pregnenolone, progesterone and DHEA declines, while that of cortisol and aldosterone stays the same or even increases. Pregnenolone, Progesterone And DHEA Drop, Cortisol Rises In Aging The decline in...
    • haidut
    • Thread
    • aging decline dhea dhea-s disease estradiol estrogen frailty menopause
    • Replies: 19
    • Forum: Scientific Studies
  9. haidut

    Low DHEA-S Predicts Fractures In Older Men

    There is a big push to start treating older men with estrogen, just as women are, because estrogen is "good for the bone". No evidence exists to support this approach and in fact multiple studies in women have shown that low DHEA, and not estrogen, is what is associated with weak bones. In...
    • haidut
    • Thread
    • androgen bone deficiency dhea dhea-s fractures men older
    • Replies: 3
    • Forum: Scientific Studies
  10. BigYellowLemon

    Effects Of Morphine Dependence And Withdrawal On Levels Of Neurosteroids In Rat Brain

    Effects of morphine dependence and withdrawal on levels of neurosteroids in rat brain. - PubMed - NCBI It's a rat study but I think the results are applicable to humans. "The chronic morphine administration (ip) resulted in a marked decrease in the brain concentrations of pregnenolone (PREG)...
    • BigYellowLemon
    • Thread
    • allopregnanolone dhea dhea-s morphine naloxone naltrexone neurosteroid opioids pregnenolone progesterone steroids
    • Replies: 5
    • Forum: Scientific Studies
  11. haidut

    Pregnenolone (and DHEA) May Protect From Heart Disease

    In some of his recent emails to people Ray recommended pregnenolone as a substance that lowers prostaglandins and inflammation. This mechanism of action also happens to be the officially proposed one for the benefits in heart disease seen with aspirin use. I was looking for the studies to...
    • haidut
    • Thread
    • cvd dhea dhea-s heart disease pregnenolone pregnenolone sulfate protective trpm3
    • Replies: 0
    • Forum: Scientific Studies
  12. haidut

    Acne At An Age Older Than 25 May Be A Sign Of Systemic Disease

    The topic of acne has come up many times on this forum and appears to be anything but solved. While the pubertal and late teen acne is relatively well understood and often responds quite well to antibiotics or hormonal therapy, acne at an older age is much less understood. The predominant view...
    • haidut
    • Thread
    • acne cortisol dhea dhea-s hyperandrogenism pcos prolactin sign systemic systemic disease testosterone
    • Replies: 33
    • Forum: Scientific Studies
  13. haidut

    Even Minor Stress Substantially Decreases DHEA-S Levels

    Most endocrinologists are at a loss when asked what leads to lower DHEA-S levels. The generic response is "aging" but the DHEA-S have been steadily declining over the last 30 years (just as testosterone) in young people, so that explanation does not add up. While Peat has not directly written...
    • haidut
    • Thread
    • chronic stress decline depletion dhea dhea-s lower mild stress response stress
    • Replies: 12
    • Forum: Scientific Studies
  14. J

    DHEA-S Associated With MPB

    Danny Roddy just posted the following: https://t.co/d3k6taYCfC This makes me wonder whether Pansterone is contributing to a recent bout of hair loss. I initially felt good on Pansterone, but now don't notice much on ~2-3 drops a day. Perhaps I have too much DHEA/DHEAs. Or maybe it's just a...
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