I have been studying the topic of copper for a long time. I previously linked copper toxicity to my, ADHD(ADHD and copper toxicity). But I also have low cerruloplasmin and copper deficiency symptoms such as fatigue and balance problems. I intuitively understood that a person can be toxic and deficient in copper at the same time, but I could not find an explanation for this. I also noticed that among ex-vegans there are many copper-toxic ones.
So my guess is that copper sources can be divided into 2 parts. "Toxic" copper from plant sources such as cereals, seeds, nuts, mushrooms, legumes, chocolate. Copper from supplements too. This copper must be bound to a carrier protein in the body. For example, cerruloplasmin. But, if a person lacks of vitamins, for example B1 or B12; or some other unknown cofactors; or some kind of genetic limitation... A person will accumulate this "toxic" copper.
And there is "good" copper, that's already associated with functional proteins. We can get it from animal products, from meat.
It seems that animals in nature, such as primates, get mostly "good" copper from animal sources, while only humans eat legumes, nuts, chocolate, etc. in large quantities.
In general, if you have copper toxicity, I think, you should focus on the "good" copper and avoid the "bad".
Some people wrote that their cerruloplasmin went up after they started chelating copper. I think that an excess of "toxic" copper itself can create problems with copper metabolism, which is one more reason to avoid it.
About the beef liver. The liver is known to store excess copper, so it is likely to contain a lot of both "good" and "bad" copper. Therefore, I do not recommend eating it. The kidneys, I think, are the same.
I'm not sure about molluscs. They are very different from mammals and can use other functional proteins, so I don't know if it's worth eating them or not... I think we should try to eat mammalian meat. I think the best sources of copper we have are beef heart and tongue. If you eat a lot of muscle meat, you should also get enough good copper.
By the way, the database I use states that venison and goat meat contain much more copper than beef.
In general, I suggest a diet of white rice, meat, beef heart, tongue. Dairy products, if you like. But make sure you get enough copper.
Be careful with sugar, because it can deplete copper:
@BearWithMe @Motif @Astolfo
So my guess is that copper sources can be divided into 2 parts. "Toxic" copper from plant sources such as cereals, seeds, nuts, mushrooms, legumes, chocolate. Copper from supplements too. This copper must be bound to a carrier protein in the body. For example, cerruloplasmin. But, if a person lacks of vitamins, for example B1 or B12; or some other unknown cofactors; or some kind of genetic limitation... A person will accumulate this "toxic" copper.
And there is "good" copper, that's already associated with functional proteins. We can get it from animal products, from meat.
It seems that animals in nature, such as primates, get mostly "good" copper from animal sources, while only humans eat legumes, nuts, chocolate, etc. in large quantities.
In general, if you have copper toxicity, I think, you should focus on the "good" copper and avoid the "bad".
Some people wrote that their cerruloplasmin went up after they started chelating copper. I think that an excess of "toxic" copper itself can create problems with copper metabolism, which is one more reason to avoid it.
About the beef liver. The liver is known to store excess copper, so it is likely to contain a lot of both "good" and "bad" copper. Therefore, I do not recommend eating it. The kidneys, I think, are the same.
I'm not sure about molluscs. They are very different from mammals and can use other functional proteins, so I don't know if it's worth eating them or not... I think we should try to eat mammalian meat. I think the best sources of copper we have are beef heart and tongue. If you eat a lot of muscle meat, you should also get enough good copper.
By the way, the database I use states that venison and goat meat contain much more copper than beef.
In general, I suggest a diet of white rice, meat, beef heart, tongue. Dairy products, if you like. But make sure you get enough copper.
Be careful with sugar, because it can deplete copper:
Fructose Induces Copper And Ceruloplasmin Deficiency?
Anyone have any comments on this? Has Ray Peat ever mentioned this concern? (PDF) The fructose–copper connection: Added sugars induce fatty liver and insulin resistance via copper deficiency
raypeatforum.com
@BearWithMe @Motif @Astolfo